Inhibitor of p38 MAP kinase

US11634406B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11634406-B2
Application numberUS-202017031190-A
CountryUS
Kind codeB2
Filing dateSep 24, 2020
Priority dateFeb 14, 2014
Publication dateApr 25, 2023
Grant dateApr 25, 2023

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A compound has the following formula:The compound is a p38 MAP kinase inhibitor. The compound and its pharmaceutically acceptable salts can be used for treatment of conditions, such as inflammatory diseases.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treatment of a condition selected from exacerbation of COPD and exacerbation of asthma comprising administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, including all stereoisomers and tautomers thereof. 2. The method of claim 1 , wherein the exacerbation of COPD or exacerbation of asthma is a virally induced exacerbation. 3. The method of claim 1 , wherein the condition is exacerbation of COPD. 4. The method of claim 1 , wherein the COPD is selected from a group consisting of chronic bronchitis and emphysema. 5. The method of claim 1 , wherein the asthma is pediatric asthma. 6. The method of claim 1 , wherein the compound of formula (I) or a pharmaceutically acceptable salt thereof, including all stereoisomers and tautomers thereof is administered as a dry-powder formulation for inhalation. 7. The method of claim 6 , wherein the dry-powder formulation for inhalation comprises lactose. 8. The method of claim 1 , further comprising administering an antiviral agent. 9. The method of claim 1 , wherein the compound of formula (I) is in its free base form. 10. The method of claim 1 , wherein the compound of formula (I) is in anhydrous solid crystalline form.

Assignees

Inventors

Classifications

  • Artificial tears; Irrigation solutions · CPC title

  • Ortho-condensed systems · CPC title

  • Bronchodilators · CPC title

  • Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine · CPC title

  • of carboxylic acids · CPC title

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Frequently asked questions

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What does patent US11634406B2 cover?
A compound has the following formula:The compound is a p38 MAP kinase inhibitor. The compound and its pharmaceutically acceptable salts can be used for treatment of conditions, such as inflammatory diseases.
Who is the assignee on this patent?
Respivert Ltd
What technology area does this patent fall under?
Primary CPC classification A61K9/0075. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Apr 25 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).