Devices, systems, and methods for treatment of intracranial aneurysms

Patent metadata

Field	Value
Publication number	US-11633818-B2
Application number	US-202016949568-A
Country	US
Kind code	B2
Filing date	Nov 3, 2020
Priority date	Nov 4, 2019
Publication date	Apr 25, 2023
Grant date	Apr 25, 2023

Abstract

Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity via an elongated shaft and transforming a shape of the occlusive member within the cavity. The method may include introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall. In some embodiments, the elongated shaft is detachably coupled to a distal portion of the occlusive member.

First claim

We claim:

1. A system comprising:
an elongate shaft defining a lumen;
an elongate member slidably disposed within the lumen of the elongate shaft, the elongate member having a proximal end region and a distal end region, wherein the distal end region is configured to be intravascularly positioned at or within an aneurysm cavity; and
an occlusive member constrained within the lumen of the shaft, the occlusive member including a proximal end portion having an opening and a distal end portion detachably coupled to the distal end region of the elongate member, wherein the elongate member extends through the opening, and wherein the occlusive member comprises one or more preferential bending regions about all or a portion of the circumference of the occlusive member, and
wherein pushing the elongate member from a distal opening in the elongate shaft pulls the occlusive member distally through the distal opening to expel the occlusive member from the shaft and allow the occlusive member to expand to a first expanded state in which the occlusive member has a first shape and the one or more preferential bending regions are positioned between the proximal and distal end portions of the occlusive member, and
wherein, when the occlusive member is in the first expanded state in the aneurysm cavity and coupled to the elongate member, proximal movement of the elongate member collapses a distal wall of the occlusive member proximally towards a proximal wall of the occlusive member, thereby transforming the occlusive member into a second expanded state in which the occlusive member has a second shape different than the first shape and the one or more preferential bending regions are closer to the aneurysm dome than both of the proximal and distal end portions.

2. The system of claim 1 , further comprising an embolic element configured to be delivered to the aneurysm cavity through the elongate member while the elongate member is coupled to the distal end portion of the occlusive member.

3. The system of claim 2 , wherein the embolic element is a liquid embolic, one or more embolic coils, or both.

4. The system of claim 1 , wherein a portion of the occlusive member surrounding the elongate member at the opening is configured to slide relative to the elongate member as the occlusive member self-expands.

5. The system of claim 1 , wherein all or a portion of the one or more preferential bending regions comprise a radiopaque material.

6. The system of claim 1 , wherein the first expanded state is a globular shape and the second expanded state is a bowl shape.

7. The system of claim 1 , wherein the distal wall conforms to the proximal wall when the occlusive member is in the second expanded state.

8. The system of claim 1 , wherein the occlusive member comprises a plurality of braided filaments.

9. The system of claim 1 , wherein the proximal end portion of the occlusive member does not include a connector.

10. The system of claim 1 , wherein, in the second expanded state the occlusive member comprises at least two mesh layers, and wherein the occlusive member is configured to be positioned in the aneurysm such that the at least two mesh layers are positioned at a neck of the aneurysm.

11. A system comprising:
an elongate shaft defining a lumen;
an elongate member slidably disposed within the lumen of the elongate shaft, the elongate member having a proximal end region and a distal end region, wherein the distal end region is configured to be intravascularly positioned at or within an aneurysm cavity; and
an occlusive member constrained within the lumen of the shaft, the occlusive member including a proximal end portion having an opening and a distal end portion detachably coupled to the distal end region of the elongate member, wherein the elongate member extends through the opening, and wherein, when the occlusive member is constrained within the lumen of the elongate shaft, the distal end portion is distal of the proximal end portion,
wherein pushing the elongate member from a distal opening in the elongate shaft pulls the occlusive member distally through the distal opening to expel the occlusive member from the elongate shaft and allow the occlusive member to expand to a firsts expanded state in which the occlusive member has a globular shape including a first wall portion proximate a dome of the aneurysm and a second wall portion proximate a neck of the aneurysm, and
wherein, when the occlusive member is in the first expanded state in the aneurysm cavity and coupled to the elongate member, proximal movement of the elongate member collapses the first wall portion towards the second wall portion, thereby transforming the occlusive member into a second expanded state in which the occlusive member has a bowl shape.

12. The system of claim 11 , further comprising an embolic element configured to be delivered to the aneurysm cavity through the elongate member while the elongate member is coupled to the distal end portion of the occlusive member.

13. The system of claim 12 , wherein the embolic element is a liquid embolic, one or more embolic coils, or both.

14. The system of claim 11 , wherein a portion of the occlusive member surrounding the elongate member at the opening is configured to slide relative to the elongate member as the occlusive member self-expands.

15. The system of claim 11 , wherein the occlusive member comprises one or more preferential bending regions about all or a portion of the circumference of the occlusive member.

16. The system of claim 15 , wherein all or a portion of the one or more preferential bending regions comprise a radiopaque material.

17. The system of claim 11 , wherein the occlusive member comprises a plurality of braided filaments.

18. The system of claim 11 , wherein the proximal end portion of the occlusive member does not include a connector.

Assignees

• Covidien Lp

Inventors

• Rhee Richard
• Divino Vincent
• Nageswaran Ashok
• Li Junwei

Classifications

• B23P19/047 Primary

  for flexible profiles, e.g. sealing or decorating strips in grooves or on other profiles by devices moving along the flexible profile (hand tools therefor B25B27/0092) · CPC title

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61B17/1214

  Coils or wires · CPC title

• A61B2017/00526

  Methods of manufacturing · CPC title

• A61B2017/00929

  isolating electrical current · CPC title