Method and system to detect r-waves in cardiac arrhythmic patterns

Patent metadata

Field	Value
Publication number	US-11633141-B2
Application number	US-202117242561-A
Country	US
Kind code	B2
Filing date	Apr 28, 2021
Priority date	May 7, 2018
Publication date	Apr 25, 2023
Grant date	Apr 25, 2023

Abstract

Computer implemented methods and systems for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains a far field cardiac activity (CA) data set that includes far field CA signals for beats. The method applies a feature enhancement function to the CA signals to form an enhanced feature in the CA data set. The method calculates an adaptive sensitivity level and sensitivity limit based on the enhanced feature from one or more beats within the CA data set and automatically iteratively analyzes a beat segment of interest by comparing the beat segment of interest to the current sensitivity level to determine whether one or more R-waves are present within the beat segment of interest. The method repeats the iterative analyzing operation while progressively adjusting the current sensitivity level until i) the one or more R-waves are detected in the beat segment of interest and/or ii) the current sensitivity level reaches the sensitivity limit. The method detects an arrhythmia within the beat segment of interest based on a presence or absence of the one or more R-waves and records results of the detecting of the arrhythmia.

First claim

What is claimed is:

1. A computer implemented method for detecting arrhythmias in cardiac activity, comprising:
under control of one or more processors configured with specific executable instructions,
obtaining a far field cardiac activity (CA) data set that includes far field CA signals for beats;
automatically iteratively analyzing beat segments of interest, from the CA signals, by comparing the beat segments of interest to a corresponding current sensitivity level to determine whether one or more R-waves are present within the corresponding beat segment of interest;
while iteratively analyzing the beat segments of interest, progressively adjusting the current sensitivity level until i) the one or more R-waves are detected in the beat segment of interest and/or ii) the current sensitivity level reaches a sensitivity limit; and
detecting an arrhythmia within the beat segment of interest based on a presence or absence of the one or more R-waves; and
recording results of the detecting of the arrhythmia.

2. The method of claim 1 , wherein the detecting the arrhythmia detects a bradycardia episode, as the arrythmia, when on a number of X beats are within a bradycardia zone out of a total of Y beats within the CA data set.

3. The method of claim 1 , further comprising applying a feature enhancement function to the CA signals to form an enhanced feature in the CA data set; and performing the analyzing operation upon the CA data set with the enhanced feature.

4. The method of claim 3 , further calculating the sensitivity level and the sensitivity limit based on the enhanced feature from one or more beats within the CA data set.

5. The method of claim 1 , wherein the calculating and automatically iteratively analyzing operations are performed as a second pass confirmation for an arrhythmia episode declared by a first pass arrhythmia detection algorithm implemented by an implantable device.

6. The method of claim 5 , wherein the CA data set includes device documented markers in combination with the CA signals, the CA data set generated by the implantable device in connection with the first pass arrhythmia detection algorithm, the first pass arrhythmia detection algorithm declaring the arrhythmia episode to be one of a bradycardia, tachycardia, asystole or atrial fibrillation episode.

7. The method of claim 1 , wherein the sensitivity level is determined based on a comparison of an ensemble R-wave peak, ensemble T-wave peak and ensemble P-wave peak amplitudes and/or variability that represent amplitudes and/or variability for the one or more R-waves.

8. The method of claim 1 , wherein the analyzing operation comprises analyzing the beat segment of interest iteratively while adjusting the sensitivity level to increase resolution during each iterative analysis until reaching the sensitivity limit or specific exiting criteria.

9. The method of claim 1 , further comprising confirming or denying an asystole episode when the beat segment of interest exhibits no detected electrical activity for a period of time that exceeds an asystole threshold.

10. The method of claim 1 , further comprising applying a feature enhancement function to the CA signals to form an enhanced feature in the CA data set, wherein the applying the feature enhancement function enhances at least one of an R-wave feature, T-wave feature, P-wave feature and/or suppresses noise.

11. The method of claim 10 , wherein the feature enhancement function includes applying a normalization function and a non-linear scaling function to the CA signals.

12. The method of claim 1 , wherein the calculating the sensitivity level further comprises determining amplitudes for one or more features of the beat segment of interest, the sensitivity level based on the amplitudes; and wherein the comparing operation includes determining whether at least a portion of the beat segment of interest exceed the current sensitivity level.

Assignees

• Pacesetter Inc

Inventors

• Dawoud Fady
• Qu Fujian
• Rosenberg Stuart
• Bornzin Gene A
• Gill Jong
• Malhotra Neha
• Min Xiaoyi

Classifications

• A61B5/29

  for permanent or long-term implantation · CPC title

• A61B5/352 Primary

  Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval · CPC title

• A61B5/363

  Detecting tachycardia or bradycardia · CPC title

• A61B5/361

  Detecting fibrillation · CPC title

• A61N1/3756 Primary

  Casings with electrodes thereon, e.g. leadless stimulators · CPC title