Method for RNA detection and quantification
US-10444224-B2 · Oct 15, 2019 · US
Coupled recognition/detection system for in vivo and in vitro use
US11629131B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11629131-B2 |
| Application number | US-201916286333-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 26, 2019 |
| Priority date | Feb 18, 2009 |
| Publication date | Apr 18, 2023 |
| Grant date | Apr 18, 2023 |
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- Title
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Abstract
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The present invention relates to novel fluorophores and their use in combination with novel nucleic acid molecules, called aptamers, that bind specifically to the fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described.
First claim
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What is claimed: 1. A compound having the structure: 2. A compound having the structure:
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Macromolecular compounds, i.e. oligomers, polymers, dendrimers · CPC title
- C07D233/96Primary
having three double bonds between ring members or between ring members and non-ring members · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
one >CH- group, e.g. cyanines, isocyanines, pseudocyanines · CPC title
Methine dyes, e.g. cyanine dyes · CPC title
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- What does patent US11629131B2 cover?
- The present invention relates to novel fluorophores and their use in combination with novel nucleic acid molecules, called aptamers, that bind specifically to the fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target mo…
- Who is the assignee on this patent?
- Univ Cornell
- What technology area does this patent fall under?
- Primary CPC classification C07D233/96. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 18 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).