Uncaging stent

Patent metadata

Field	Value
Publication number	US-11622872-B2
Application number	US-202016786736-A
Country	US
Kind code	B2
Filing date	Feb 10, 2020
Priority date	May 16, 2016
Publication date	Apr 11, 2023
Grant date	Apr 11, 2023

Abstract

A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.

First claim

What is claimed is:

1. An endoluminal prosthesis comprising:
a scaffold having a plurality of circumferential rings patterned from a non-degradable material, said scaffold being configured to expand from a crimped configuration to an expanded configuration, at least some adjacent circumferential rings comprise separation regions and said some adjacent circumferentially separable rings are joined at attachment points at the separation regions through circumferentially separable axial links, said separation regions configured to separate after expansion of the scaffold in a physiological environment;
wherein at least some of the circumferentially separable axial links comprise a first segment and a second segment, wherein the first and second segments are divided by an axially extending dividing line, are held together while the scaffold is in the crimped configuration, and are configured circumferentially separate when the scaffold is in the expanded configuration; and
wherein after expansion the segments circumferentially separate and the circumferential rings circumferentially open at the separation regions separate at the attachment points while each segment of the axial link remains attached to said attachment points on said adjacent circumferential rings;
wherein said scaffold is configured to form one continuous loop after all circumferentially separable rings and circumferentially separable axial links have separated;
and wherein the circumferentially separable rings and circumferentially separable axial links comprise a pre-formed break or gap, said preformed gap or break is joined by, covered by, or embedded in a biodegradable polymer and/or adhesive which degrades in the physiologic environment.

2. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between crowns on adjacent circumferential rings.

3. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between struts on adjacent circumferential rings.

4. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between a crown on one circumferential rings and a struts on an adjacent circumferential rings.

5. An endoluminal prosthesis as in claim 1 , wherein said at least some circumferentially separable axial links are arranged in an axial line along the scaffold.

6. An endoluminal prosthesis as in claim 1 , wherein said at least some circumferentially separable axial links are arranged in a helical line along the scaffold.

7. An endoluminal prosthesis as in claim 1 , wherein said at least some circumferentially separable axial links are arranged in two or three lines along the scaffold.

8. An endoluminal prosthesis as in claim 1 , wherein at least a portion of the axially extending dividing line is non-linear.

9. An endoluminal prosthesis as in claim 1 , wherein the entire axially extending dividing line is non-linear.

10. An endoluminal prosthesis as in claim 9 , wherein the axially extending dividing line comprises includes one or more curved sections and one or more linear sections.

11. An endoluminal prosthesis as in claim 10 , wherein the curved section includes regions of different curvature.

12. An endoluminal prosthesis as in claim 10 , wherein the curved section includes regions of reversing curvature.

13. An endoluminal prosthesis as in claim 10 , wherein at least some of the turns are 135° or greater.

14. An endoluminal prosthesis as in claim 10 , wherein at least some of the turns are 180° or greater.

15. An endoluminal prosthesis as in claim 10 , wherein the axially extending dividing line has one or more straight portions joined to one or more curves sections.

16. An endoluminal prosthesis as in claim 10 , wherein the axially extending dividing line has a curved region attached to the attachments point on one circumferential ring followed by a straight region followed by a curved region attached to the attachment point on the adjacent circumferential ring.

17. An endoluminal prosthesis as in claim 10 , wherein the axially extending dividing line has a curved region attached to the attachments point on one circumferential ring followed by a second curved region having a different direction of curvature than the first region followed by a third curved region having a different direction of curvature than the second curved region attached to the attachment point on the adjacent circumferential ring.

18. An endoluminal prosthesis as in claim 1 , wherein the axially extending dividing line an S-shape.

19. An endoluminal prosthesis as in claim 1 , wherein the axially extending dividing line has a W-shape.

20. An endoluminal prosthesis as in claim 1 , wherein the axially extending dividing line has a serpentine shape.

21. An endoluminal prosthesis as in claim 1 or 20 , wherein the biodegradable polymer and/or adhesive comprises polylactide, poly-L-lactide, poly-DL-lactide, polylactide-co-glycolide, poly(L-lactic-co-glycolide), poly(ethylene-co-vinyl acetate), poly(L-lactide-co-epsilon-caprolactone), poly(DL-lactide-co-glycolide), poly(lactide-co-caprolactone), poly(D-lactide), polyglycolide, polycaprolactone, polyhydroxyalkanoate, polyvinyl alcohol, polyvinyl acetate or cyanoacrylate.

22. An endoluminal prosthesis as in claim 1 , wherein said non-degradable material comprises a metal or metal alloy.

23. An endoluminal prosthesis comprising:
a scaffold having a plurality of circumferential rings patterned from a non-degradable material, said scaffold being configured to expand from a crimped configuration to an expanded configuration, wherein at least some adjacent circumferential rings comprise separation regions and are joined at attachment points at the separation regions on said adjacent circumferential rings through circumferentially separable axial links, said separation regions are configured to separate after expansion of the scaffold in a physiologic environment;
said circumferentially separable axial links are divided along the axial joining line into two segments each having one or more corresponding bends, curves, straight areas, angles, or any combination thereof, wherein said segments are configured to be held together and inhibit separation of the segments during expansion of the scaffold, but are configured to separate along said axial joining line following expansion of said scaffold in a physiologic environment,
wherein after expansion the segments circumferentially separate and the circumferential rings circumferentially open at the separation regions at the attachment points, while said adjacent circumferentially separable rings remain axially attached through said segments at said attachment points;
wherein said scaffold is configured to form one continuous loop after all circumferentially separable rings and circumferentially separable axial links have separated; and wherein the circumferentially separable rings and circumferentially separable axial links comprise a pre-formed break or gap, said preformed gap or break is joined by, covered by, or embedded in a biodegradable polymer and/or adhesive which degrades in the physiologic environment.

Assignees

• Elixir Medical Corp

Inventors

• Sirhan Motasim
• Yan John
• Bhat Vinayak
• Paraschac Joseph
• Cryer Brett
• Serna Benjamyn

Classifications

• A61F2210/0014

  using shape memory or superelastic materials, e.g. nitinol · CPC title

• A61F2210/0076

  multilayered, e.g. laminated structures · CPC title

• A61F2250/0071

  breakable or frangible · CPC title

• A61F2002/91566

  connected trough to trough · CPC title

• A61F2002/91591

  Locking connectors, e.g. using male-female connections · CPC title