Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods

Patent metadata

Field	Value
Publication number	US-11617648-B2
Application number	US-202217707832-A
Country	US
Kind code	B2
Filing date	Mar 29, 2022
Priority date	Oct 19, 2011
Publication date	Apr 4, 2023
Grant date	Apr 4, 2023

Abstract

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.

First claim

We claim:

1. A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising:
a valve support expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;
a prosthetic valve mounted to the valve support and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction;
an anchoring member including a first end attached to the valve support and a second end spaced from the valve support with the prosthetic heart valve device in the radially expanded configuration, the anchoring member having interconnected struts forming an annular ring around the valve support;
a first sealing member disposed on an interior surface of the valve support;
a second sealing member coupled to an interior surface of the anchoring member; and
a third sealing member coupled to an exterior surface of the anchoring member.

2. The prosthetic heart valve device of claim 1 , wherein the second sealing member and the third sealing member are continuous.

3. The prosthetic heart valve device of claim 2 , wherein the second end of the anchoring member is not attached to the valve support, and wherein the continuous second and third sealing members wrap around the second end of the anchoring member.

4. The prosthetic heart valve device of claim 1 , wherein the first sealing member is attached to the prosthetic valve.

5. The prosthetic heart valve device of claim 1 , wherein the first sealing member, the second sealing member, and the third sealing member comprise a fabric.

6. The prosthetic heart valve device of claim 1 , wherein the first sealing member, the second sealing member, and the third sealing member comprise at least one of polyethylene terephthalate (PTE), expanded polytetrafluoroethylene (ePTFE), bovine pericardium, polymers, thermoplastic polymer, synthetic fibers, or natural fibers.

7. The prosthetic heart valve device of claim 1 , wherein the first end of the anchoring member is a downstream end, and wherein the first end of the anchoring member is attached to a downstream end of the valve support.

8. The prosthetic heart valve device of claim 7 , wherein the first end of the anchoring member includes anchoring member eyelets, the downstream end of the valve support includes valve-support eyelets, and wherein the prosthetic heart valve device further includes connectors attaching the anchoring member to the valve support at the anchoring-member eyelets and the valve-support eyelets.

9. The prosthetic heart valve device of claim 8 , wherein the connectors are selected from the group consisting of sutures, solder, welds, staples, rivets, mechanical interlocks, friction connectors, interference fit, or any combination thereof.

10. The prosthetic heart valve device of claim 9 , wherein the connectors comprise rivets.

11. The prosthetic heart valve device of claim 9 , wherein the connectors comprise sutures.

12. A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising;
a valve support expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;
a prosthetic valve mounted to the valve support and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction;
an anchoring member including a first end attached to the valve support and a second end spaced from the valve support with the prosthetic heart valve device in the radially expanded configuration;
a first sealing member disposed on an interior surface of the valve support;
a second sealing member coupled to an interior surface of the anchoring member; and
a third sealing member coupled to an exterior surface of the anchoring member,
wherein the first end of the anchoring member is an upstream end, and wherein the first end of the anchoring member is attached to an upstream end of the valve support.

13. The prosthetic heart valve device of claim 12 wherein the first end of the anchoring member includes anchoring-member eyelets, the upstream end of the valve support includes valve-support eyelets, and wherein the prosthetic heart valve device further includes connectors attaching the anchoring member to the valve support at the anchoring-member eyelets and the valve-support eyelets.

14. The prosthetic heart valve device of claim 13 , wherein the connectors are selected from the group consisting of sutures, solder, welds, staples, rivets, mechanical interlocks, friction connectors, interference-fit connectors, or any combination thereof.

15. The prosthetic heart valve device of claim 14 , wherein the connectors comprise rivets.

16. The prosthetic heart valve device of claim 14 , wherein the connectors comprise sutures.

17. The prosthetic heart valve device of claim 12 , wherein at least a portion of the anchoring member flares outwardly in a downstream direction from the first end of the anchoring member.

18. The prosthetic heart valve device of claim 17 , wherein the anchoring member extends only a partial length of the valve support such that the second end of the anchoring member is upstream of a downstream end of the valve support.

19. A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising:
a valve support expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;
a prosthetic valve mounted to the valve support and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction;
an anchoring member including a first end attached to the valve support and a second end spaced from the valve support with the prosthetic heart valve device in the radially expanded configuration, wherein the anchoring member is configured such that an outer surface of the anchoring member engages an inner surface of the native annulus;
a first sealing member disposed on an interior surface of the valve support;
a second sealing member coupled to an interior surface of the anchoring member; and
a third sealing member coupled to an exterior surface of the anchoring member.

Assignees

• Twelve Inc

Inventors

• Morriss John
• Mclean Matt
• Bensing Maureen
• Dueri Jean-Pierre
• Gifford Iii Hanson
• Miyashiro Katie
• Scott David Jerry
• Trask David
• Valley Kirsten

Classifications

• A61F2/2436

  Deployment by retracting a sheath · CPC title

• A61F2230/0054

  V-shaped · CPC title

• A61F2230/0069

  cylindrical · CPC title

• A61F2/2418 Primary

  Scaffolds therefor, e.g. support stents · CPC title

• A61F2/2409

  Support rings therefor, e.g. for connecting valves to tissue (annuloplasty rings A61F2/2442) · CPC title