Apparatus, system and methodologies for biopsy or removal of tissue or adding material to tissue using a magnetically-actuated capsule

Patent metadata

Field	Value
Publication number	US-11607285-B2
Application number	US-201816053247-A
Country	US
Kind code	B2
Filing date	Aug 2, 2018
Priority date	Aug 2, 2017
Publication date	Mar 21, 2023
Grant date	Mar 21, 2023

Abstract

Disclosed embodiments provide a biopsy tool and methodologies for obtain biopsies and/or a tool and methodology that may be used to add material to a subject's tissue.

First claim

What is claimed:

1. An apparatus comprising:
a capsule containing at least one aperture for removing or adding tissue from or to a subject's body part, the capsule having at least one magnetizable section containing a magnetizable material;
a tube for manipulating the capsule therein and also including at least one aperture; and
magnetic field generating means for generating and applying one or more magnetic fields to the subject's body part,
wherein the manipulation of the capsule within the tube is performed using the magnetizable material influenced by the one or more magnetic fields, and
wherein at least one portion of the magnetic field generating means is external to the subject's body part.

2. The apparatus of claim 1 , wherein the aperture of the capsule is configured to be manipulated with respect to the tube via the one or more magnetic fields and wherein the capsule is removed from the tube to remove tissue from the subject's body part.

3. The apparatus of claim 1 , wherein the aperture of the capsule is configured to be inserted into the tube and manipulated with respect to the tube via the one or more magnetic fields to add tissue to the subject's body part.

4. The apparatus of claim 1 , wherein air or another gas, fluid, a wire or a spring or a combination of one or more of these elements, is introduced through the tube to facilitate removing tissue from the subject's body part.

5. The apparatus of claim 1 , wherein air or another gas, fluid, a wire or a spring or a combination of one or more of these elements, is introduced through the tube to facilitate adding tissue, cells, or materials to or within the subject's body part.

6. The apparatus of claim 1 , wherein air or another gas, fluid or a wire or spring or a combination of one or more of these elements, is introduced through the tube to facilitate additional movement of the capsule with respect to the tube or with respect to the subject's body part.

7. The apparatus of claim 1 , wherein the tube includes means for attachment to a surgical or biopsy robot or a mechanical/magnetic/optical tracker.

8. The apparatus of claim 1 , further comprising means for performing magnetic imaging of the subject's body part, wherein manipulation of the capsule or the tube into or in the subject's body part is performed under imaging guidance provided by the magnetic imaging.

9. The apparatus of claim 1 , wherein the one or more magnetic fields have transition times that are too small to trigger unwanted side effects in the subject's body part.

10. The apparatus of claim 1 , wherein the capsule has a length of 10 cm or less.

11. The apparatus of claim 1 , wherein manipulation of the tube is performed using the magnetizable material of the capsule influenced by one or more further magnetic fields.

12. A method for removing tissue from a body part or adding material to a subject's body part, the method comprising:
introducing a tube into the subject's body part, wherein the tube includes a capsule containing at least one aperture for removing or adding tissue from or to a subject's body part, the capsule having at least one magnetizable section containing a magnetizable material, wherein the tube also includes at least one aperture; and
magnetically manipulating the capsule located within the tube within the subject's body part by generating and applying one or more magnetic fields to the magnetizable material in the subject's body part,
wherein the one or more magnetic fields are generated outside and applied to the subject's body part by a system that is at least in part external to the subject's body.

13. The method of claim 12 , further comprising manipulating the aperture of the capsule with respect to the tube via the one or more magnetic fields and removing the capsule from the tube to remove tissue from the subject's body part.

14. The method of claim 13 , further comprising manipulating the tube by further magnetically manipulating the capsule located in the tube within the subject's body part by generating and applying one or more further magnetic fields to the magnetizable material.

15. The method of claim 12 , further comprising inserting the capsule into the tube and manipulating the aperture of the capsule with respect to the tube via the one or more magnetic fields to add tissue to the subject's body part.

16. The method of claim 12 , further comprising introducing air or another gas, fluid, a wire or a spring through the tube to facilitate removing tissue from the subject's body part.

17. The method of claim 12 , further comprising introducing air or another gas, fluid, a wire or a spring through the tube to facilitate adding tissue, cells, or materials to or within the subject's body part.

18. The method of claim 12 , further comprising introducing air or another gas, fluid, a wire or a spring through the tube to facilitate additional movement of the capsule with respect to the tube or with respect to the subject's body part.

19. The method of claim 12 , further comprising attaching the tube to a surgical or biopsy robot or a mechanical/magnetic/optical tracker.

20. The method of claim 12 , wherein manipulation of the capsule or the tube into or in the subject's body part is performed with propulsion applied using dynamic inversion.

21. The method of claim 12 , further comprising magnetic imaging the subject's body part, wherein manipulation of the capsule or the tube into or in the subject's body part is performed under imaging guidance provided by the magnetic imaging.

22. The method of claim 12 , wherein the one or more magnetic fields have transition times that are too small to trigger unwanted side effects in the subject's body part.

23. The method of claim 12 , wherein the capsule has a length of 10 cm or less.

Assignees

• Weinberg Medical Physics Inc

Inventors

• Weinberg Irving N
• Vohra Amit

Classifications

• A61B10/02 Primary

  Instruments for taking cell samples or for biopsy {(A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48)} · CPC title

• A61B10/0283

  with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe (A61B10/025, A61B10/0266 take precedence) · CPC title

• A61B2034/2059

  Mechanical position encoders · CPC title

• A61B5/05

  Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves (measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24) · CPC title

• A61B10/04

  Endoscopic instruments, e.g. catheter-type instruments · CPC title