Sensory threshold adaptation for neurological therapy screening and/or electrode selection, and associated systems and methods

Patent metadata

Field	Value
Publication number	US-11602634-B2
Application number	US-202016746556-A
Country	US
Kind code	B2
Filing date	Jan 17, 2020
Priority date	Jan 17, 2019
Publication date	Mar 14, 2023
Grant date	Mar 14, 2023

Abstract

Systems and methods for using sensory threshold and/or adaptation for neurological therapy screening and/or parameter selection. A representative method for establishing a treatment regimen for a patient includes: in response to a first indication of a characteristic of the patient's sensory response to an electrical stimulus, providing a second indication indicating suitability of an electrical signal for delivery to the patient to address a patient condition, wherein the electrical signal has a frequency in a frequency range from 1.2 kHz to 100 kHz.

First claim

I claim:

1. A method for establishing a treatment regimen for a patient, comprising:
receiving a first indication of a level of adaptation of the patient's sensory response to a suprathreshold electrical stimulus:
in response to the first indication, providing a second indication indicating suitability of an electrical signal for delivery to the patient to address a patient condition, wherein the electrical signal has a frequency in a frequency range from 1.2 kHz to 100 kHz; and
in response to the second indication indicating that the electrical signal is suitable, programming a patient treatment system to generate and deliver the electrical signal to the patient to address the patient condition.

2. The method of claim 1 , further comprising delivering the electrical signal to the patient to address the patient condition.

3. The method of claim 1 wherein the level of adaptation includes a decrease in sensitivity of the patient's sensory response over time.

4. The method of claim 1 wherein the level of adaptation includes a change in an intensity of the patient's sensory response.

5. The method of claim 4 wherein the change is a decrease in the intensity.

6. The method of claim 4 , further comprising determining the change by delivering the electrical stimulus at multiple points in time.

7. The method of claim 6 wherein the electrical stimuli are delivered over a period of an hour or less.

8. The method of claim 1 wherein the patient condition includes pain.

9. The method of claim 1 wherein the frequency of the electrical stimulus is also in a frequency range from 1.2 kHz to 100 kHz.

10. The method of claim 1 wherein a frequency of the electrical stimulus is different than the frequency of the electrical signal.

11. The method of claim 1 wherein the electrical stimulus is generated by a signal generator positioned external to the patient.

12. A system for establishing a treatment regimen for a patient, comprising:
a machine-readable medium having first instructions and second instructions,
wherein the first instructions, when executed:
receive a first indication of a level of adaptation of the patient's sensory response to a suprathreshold electrical stimulus, and
in response to the first indication, provide a second indication indicating suitability of an electrical signal for delivery to the patient to address a patient condition, wherein the electrical signal has a frequency in a frequency range from 1.2 kHz to 100 kHz, and

wherein the second instructions, when executed in response to the second indication indicating that the electrical signal is suitable:
deliver the electrical signal to the patient via an implanted signal delivery device to address the patient condition.

13. The system of claim 12 wherein the machine-readable medium is housed, at least in part, in an implantable device configured to be implanted in the patient.

14. The system of claim 12 wherein the machine-readable medium is housed, at least in part, in an external device configured to operate external to the patient.

15. The system of claim 12 wherein the level of adaptation includes a decrease in sensitivity of the patient's sensory response over time.

16. The system of claim 12 wherein the level of adaptation includes a change in an intensity of the patient's sensory response.

17. The system of claim 16 wherein the change is a decrease in the intensity.

18. The system of claim 12 wherein a frequency of the electrical stimulus is the same as the frequency of the electrical signal.

19. The system of claim 12 wherein a frequency of the electrical stimulus is different than the frequency of the electrical signal.

20. The system of claim 12 wherein the patient indication includes pain.

21. A method for establishing a treatment regimen for a patient, comprising:
determining a level of adaptation of the patient's sensory response to a suprathreshold electrical stimulus:
based on the level of adaptation, providing an indication indicating suitability of an electrical signal for delivery to the patient to address a patient condition, wherein the electrical signal has a frequency in a frequency range from 1.2 kHz to 100 kHz; and
in response to the indication indicating that the electrical signal is suitable, programming a patient treatment system to generate and deliver the electrical signal to the patient to address the patient condition.

Assignees

• Nevro Corp

Inventors

• Lee Dongchul

Classifications

• A61N1/3615

  Intensity · CPC title

• G16H40/60

  for the operation of medical equipment or devices · CPC title

• G16H20/30 Primary

  relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising · CPC title

• A61N1/36071 Primary

  Pain · CPC title

• A61N1/3904

  External heart defibrillators [EHD] · CPC title