Porous fiber, adsorbent material, and purification column

Patent metadata

Field	Value
Publication number	US-11596922-B2
Application number	US-201716096530-A
Country	US
Kind code	B2
Filing date	Apr 20, 2017
Priority date	Apr 27, 2016
Publication date	Mar 7, 2023
Grant date	Mar 7, 2023

Abstract

A solid fiber is described, where the solid fiber is characterized by (a) a modification degree Do/Di, in a cross section of the solid fiber of 1.20 to 8.50 where the inscribed circle diameter is denoted by Di and the circumscribed circle diameter is denoted by Do; and (b) a porous specific surface area of not less than 30 m2/g.

First claim

The invention claimed is:

1. A porous fiber having pores inside the fiber and comprising a modified solid cross-section, wherein the porous fiber satisfies the following (a) and (b):
(a) a modification degree Do/Di in the modified solid cross-section is 1.20 to 8.50 where an inscribed circle diameter of the modified solid cross-section is denoted by Di and a circumscribed circle diameter of the modified solid cross-section is denoted by Do; and
(b) a porous specific surface area of the fiber is not less than 170 m 2 /g.

2. The porous fiber according to claim 1 , wherein an inscribed circle occupancy of the following equation is not less than 0.10:
Inscribed circle occupancy=Area of the inscribed circle of a cross section of the fiber/Area of the cross section of the fiber.

3. The porous fiber according to claim 1 , wherein a diameter of the pores in the porous fiber is not more than 25 μm and a ratio of an average diameter of the pores in the area adjacent to the outer surface of the fiber versus an average diameter of the pores in the central portion area of the fiber is not less than 0.50 and not more than 3.00.

4. The porous fiber according to claim 1 , wherein the modified solid cross-section comprises a porous portion which has a network structure composed of a communication hole and a dense layer which has a more dense structure in comparison to the porous portion, and wherein the porous fiber satisfies the following (d) to (f):
(d) the porous fiber has a continuous structure of the porous portion and the dense layer;
(e) the dense layer is located closer to the area adjacent to the outer surface of the fiber than the porous portion and a distance T 1 from the outermost surface of the fiber to the porous portion is not less than 0.001 μm and not more than 30 μm; and
(f) the network structure satisfies a pore shape index calculated by the following equation that is not less than 0.2 and not more than 6.0:
index of pore shape in a cross section in the fiber axis direction Dxy =(pore diameter in the lengthwise direction of the fiber)/(pore diameter in the cross-section direction of the fiber).

5. The porous fiber according to claim 4 , wherein both the porous portion and the dense layer contain not less than 45 vol % of a material common to both as a component material.

6. The porous fiber according to claim 1 , wherein the solid fiber is in a straight form.

7. The porous fiber according to claim 1 , wherein an open pore ratio at the surface of the porous fiber is not less than 0.5% and not more than 30%.

8. The porous fiber according to claim 1 , wherein the porous fiber has a negative charge.

9. The porous fiber according to claim 1 , wherein the porous fiber comprises an amorphous polymer material.

10. The porous fiber according to claim 1 , wherein the porous fiber comprises an amorphous polymer material and the amorphous polymer material comprises a polymer with an ester group.

11. The porous fiber according to claim 1 , wherein the number of adhered platelets which are brought into contact with the surface of the porous fiber is not more than 30/(4.3×10 3 μm 2 ).

12. An adsorbent material, comprising not less than 28 vol % of the porous fiber according to claim 1 as a fiber bundle.

13. The adsorbent material according to claim 12 , wherein the adsorbent material is for use in a medical application.

14. The adsorbent material according to claim 13 , wherein the adsorption amount of β 2 -microglobulin per fiber volume is not less than 0.005 mg/cm 3 .

15. The porous fiber according to claim 1 , wherein the modified solid cross-section comprises a porous portion which has a network structure composed of a communication hole, and a layer, and wherein the porous fiber satisfies the following (d) to (f):
(d) the porous fiber has a continuous structure of the porous portion and the layer;
(e) the layer is located closer to the area adjacent to the outer surface of the fiber than the porous portion and a distance T 1 from the outermost surface of the fiber to the porous portion is not less than 0.001 μm and not more than 30 μm; and
(f) the network structure satisfies a pore shape index calculated by the following equation that is not less than 0.2 and not more than 6.0:
index of pore shape in a cross section in the fiber axis direction Dxy =(pore diameter in the lengthwise direction of the fiber)/(pore diameter in the cross-section direction of the fiber).

16. The porous fiber according to claim 15 , wherein both the porous portion and the layer contain not less than 45 vol % of a material common to both as a component material.

Assignees

• Toray Industries

Inventors

• Fujieda Hiroaki
• Ueno Yoshiyuki
• Tanaka Kazumi

Classifications

• A61M2202/0439

  White blood cells; Leucocytes · CPC title

• B01D15/00

  Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor · CPC title

• B01J2220/58

  Use in a single column · CPC title

• B01J20/26

  Synthetic macromolecular compounds · CPC title

• B01J20/28083

  being in the range 2-50 nm, i.e. mesopores · CPC title