Dose measurement system and method

Patent metadata

Field	Value
Publication number	US-11566931-B2
Application number	US-202016861899-A
Country	US
Kind code	B2
Filing date	Apr 29, 2020
Priority date	May 21, 2012
Publication date	Jan 31, 2023
Grant date	Jan 31, 2023

Abstract

Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

First claim

The invention claimed is:

1. An apparatus for measuring liquid volume in a container, the apparatus comprising:
a plurality of light sources disposed and configured to emit electromagnetic radiation toward the container, wherein each of the plurality of light sources is configured to scatter electromagnetic radiation such that at least a portion of electromagnetic radiation emitted from a first light source of the plurality of light sources would overlap at least a portion of electromagnetic radiation emitted from a second light source of the plurality of light sources when the first light source and the second light source are switched on;
a plurality of sensors optically coupleable to the plurality of light sources, wherein a first sensor of the plurality of sensors is disposed and configured to detect the electromagnetic radiation emitted by at least two of the plurality of light sources; and
a processing unit that includes a processor, wherein the processing unit is configured to receive data representative of detected electromagnetic radiation from each of the plurality of sensors, the processing unit operable to combine the received data from each of the plurality of sensors into a signal signature representative of the electromagnetic radiation detected by the plurality of sensors,
wherein each of the plurality of sensors are discrete sensors and are separately mounted on a printed circuit board,
wherein the processing unit is configured to pulse each of the plurality of light sources such that the electromagnetic radiation is emitted in pulses, and
wherein the processing unit is configured to operate each sensor of the plurality of sensors to detect electromagnetic radiation while a light source of the plurality of light sources is switched off.

2. The apparatus of claim 1 , wherein the processing unit is further configured to associate the signal signature with a reference signature, the reference signature being representative of a liquid volume in the container.

3. The apparatus of claim 1 , wherein the plurality of light sources, the plurality of sensors and the processing unit are disposed in a housing, the housing configured to be removably coupleable to a drug delivery device.

4. The apparatus of claim 3 , wherein the drug delivery device is an injection pen.

5. The apparatus of claim 4 , wherein the housing is a pen cap.

6. The apparatus of claim 5 , wherein at least one of the injection pen and the pen cap includes alignment features configured to allow the pen cap to be coupled to the injection pen in a predetermined radial orientation.

7. The apparatus of claim 1 , wherein the processing unit includes a memory configured to temporarily store at least one of the data representative of the portion of the detected electromagnetic radiation from each of the plurality of sensors and the signal signature representative of the electromagnetic radiation detected by the plurality of sensors.

8. The apparatus of claim 1 , wherein the processing unit includes a memory configured to store a plurality of reference signatures, each of the plurality of reference signatures being representative of a liquid volume in the container.

9. The apparatus of claim 1 , wherein the processing unit includes an RFID chip configured to store information, the RFID chip configured to allow a near field communication-enabled device to read the stored information.

10. The apparatus of claim 1 , wherein the light sources are light emitting diodes.

11. The apparatus of claim 1 , wherein the sensors are photodetectors.

12. The apparatus of claim 1 , wherein the electromagnetic radiation is infrared radiation.

13. The apparatus of claim 1 , wherein the electromagnetic radiation is microwave radiation.

14. The apparatus of claim 1 , further comprising:
a communications module configured to allow two-way communication with a remote device.

15. The apparatus of claim 1 , further comprising:
an insulation structure for improving signal quality.

16. The apparatus of claim 15 , wherein the insulation structure includes a metal lining configured to shield the electronic components of the apparatus from external electromagnetic noise.

17. The apparatus of claim 1 , further comprising:
a display configured to communicate information associated with a status of the apparatus to a user.

18. The apparatus of claim 17 , wherein the status includes at least one of a dose remaining, a history of use, remaining battery life, wireless connectivity status, and user reminders.

19. The apparatus of claim 1 , further comprising:
a user input interface configured to allow the user to at least one of power ON the apparatus, power OFF the apparatus, reset the apparatus, manually input details of patient behavior, manually input details of container usage, and manually initiate communication between the apparatus and a remote device.

20. The apparatus of claim 1 , wherein the signal signature includes a combination of transmitted, reflected and refracted portions of the electromagnetic radiation detected by each of the plurality of sensors.

Assignees

• Bigfoot Biomedical Inc

Inventors

• Whalley Richard
• White James

Classifications

• G01F13/00

  Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups · CPC title

• A61M5/16886

  for measuring fluid flow rate, i.e. flowmeters · CPC title

• G01F11/021

  of the piston type (G01F11/04 takes precedence) · CPC title

• A61M5/16804

  Flow controllers · CPC title

• G01F17/00

  Methods or apparatus for determining the capacity of containers or cavities, or the volume of solid bodies (measuring linear dimensions to determine volume G01B) · CPC title