Mapping of atrial fibrillation
US-2017281031-A1 · Oct 5, 2017 · US
US11564610B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11564610-B2 |
| Application number | US-202016817537-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 12, 2020 |
| Priority date | May 23, 2019 |
| Publication date | Jan 31, 2023 |
| Grant date | Jan 31, 2023 |
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A method includes assigning, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively. Some of the locations are on an endocardial surface of the tissue, and others of the locations are on an epicardial surface of the tissue. The method further includes assigning respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. Other embodiments are also described.
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The invention claimed is: 1. A system, comprising: a monitor; and a processor, configured to: assign, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively, and some of the locations being on an endocardial surface of the tissue, and others of the locations being on an epicardial surface of the tissue, assign respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values, and display the model on the monitor. 2. The system according to claim 1 , wherein the parameter includes a property of the tissue. 3. The system according to claim 2 , wherein the property includes a local activation time (LAT). 4. The system according to claim 3 , wherein the processor is further configured to: identify, based on the first values and the second values, at least one region of decelerating electrical propagation, and generate an output indicating the region. 5. The system according to claim 1 , wherein the parameter includes an amount of energy delivered to the tissue. 6. The system according to claim 1 , wherein the processor is configured to interpolate the first values by iteratively assigning, to each voxel of the second voxels, an average of immediate neighbors of the voxel. 7. The system according to claim 6 , wherein the processor is configured to assign the average by assigning a weighted average in which the immediate neighbors are weighted by respective weights, which are derived from respective levels of confidence associated with the first values. 8. The system according to claim 6 , wherein the processor is configured to interpolate the first values by, prior to iteratively assigning the average to each voxel of the second voxels, assigning a respective initial value to each voxel of the second voxels, using any type of nearest neighbor interpolation. 9. The system according to claim 1 , wherein the processor is configured to display the model so as to indicate those of the second values assigned to the subset. 10. A method, comprising: assigning, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively, and some of the locations being on an endocardial surface of the tissue, and others of the locations being on an epicardial surface of the tissue; and assigning respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. 11. The method according to claim 10 , wherein the property includes a local activation time (LAT). 12. The method according to claim 11 , further comprising: based on the first values and the second values, identifying at least one region of decelerating electrical propagation; and generating an output indicating the region. 13. The method according to claim 10 , wherein the parameter includes an amount of energy delivered to the tissue. 14. The method according to claim 10 , wherein interpolating the first values comprises interpolating the first values by iteratively assigning, to each voxel of the second voxels, an average of immediate neighbors of the voxel. 15. The method according to claim 14 , wherein assigning the average comprises assigning a weighted average in which the immediate neighbors are weighted by respective weights, which are derived from respective levels of confidence associated with the first values. 16. The method according to claim 14 , wherein interpolating the first values further comprises, prior to iteratively assigning the average to each voxel of the second voxels, assigning a respective initial value to each voxel of the second voxels, using any type of nearest neighbor interpolation. 17. The method according to claim 10 , further comprising displaying the model so as to indicate those of the second values assigned to the subset. 18. A computer software product comprising a tangible non-transitory computer-readable medium in which program instructions are stored, which instructions, when read by a processor, cause the processor to: assign, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively, and some of the locations being on an endocardial surface of the tissue, and others of the locations being on an epicardial surface of the tissue, and assign respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. 19. The computer software product according to claim 18 , wherein the parameter includes a local activation time (LAT) of the tissue. 20. The system according to claim 1 , wherein the processor is configured to assign, to first voxels in the model of tissue of the chamber of the heart, respective first values of the parameter at respective locations on the tissue based on: determine positions of a distal end of a catheter based on signals from one or more electromagnetic sensors disposed at the distal end of the catheter; and determine the respective first values of the parameter based on signals generated by one or more additional sensors disposed at the distal end of the catheter.
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