Octahydro fused azadecalin glucocorticoid receptor modulators

US11560379B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11560379-B2
Application numberUS-202117146608-A
CountryUS
Kind codeB2
Filing dateJan 12, 2021
Priority dateNov 25, 2013
Publication dateJan 24, 2023
Grant dateJan 24, 2023

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides octahydro fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.

First claim

Opening claim text (preview).

What is claimed is: 1. The compound ((4aR,8aS)-1-(4-fluorophenyl)-6-((2-isopropyl-2H-1,2,3-triazol-4-yl)sulfonyl)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(thiazol-4-yl)methanone, having the formula 2. A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound having the formula: 3. A method of modulating a glucocorticoid receptor, comprising contacting a glucocorticoid receptor with a compound having the formula:

Assignees

Inventors

Classifications

  • Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 · CPC title

  • Antineoplastic agents · CPC title

  • Ortho-condensed systems · CPC title

  • C07D471/04Primary

    Ortho-condensed systems · CPC title

  • ortho- or peri-condensed with heterocyclic ring systems · CPC title

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Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US11560379B2 cover?
The present invention provides octahydro fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
Who is the assignee on this patent?
Corcept Therapeutics Inc
What technology area does this patent fall under?
Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jan 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 11 related publications on this page (citations in our corpus or others sharing the same primary CPC).