Medicament delivery device

Patent metadata

Field	Value
Publication number	US-11547809-B2
Application number	US-201616061052-A
Country	US
Kind code	B2
Filing date	Nov 7, 2016
Priority date	Dec 14, 2015
Publication date	Jan 10, 2023
Grant date	Jan 10, 2023

Abstract

A medicament delivery device is presented having a medicament container having an attached medicament delivery member; a housing where the medicament container is movable between a retracted and an extended position in which the medicament delivery member extends from the housing; a drive unit that advances the medicament container from its retracted position to its extended position to expel the contents through the medicament delivery member; and a medicament container holder for carrying the medicament container as it is advanced, the medicament container holder having a proximal end through which the medicament delivery member extends and a holding member releasably connected to the drive unit and attached to the medicament container holder. The holding member has a biasing element having a resilient structure in the form of a tubular wall provided with slots extending in the generally circumferential direction arranged to bias the medicament container in the proximal direction in the medicament container holder.

First claim

The invention claimed is:

1. A medicament delivery device comprising:
a medicament container comprising a syringe barrel having an attached medicament delivery member and a radially extending flange having a distal end surface;
a housing having a longitudinal axis and adapted to receive the medicament container, the medicament container being movable between a retracted position in which the medicament delivery member is contained within the housing and an extended position in which the medicament delivery member extends from the housing;
a rear end cover axially fixed relative to the longitudinal axis of the housing and fixedly attached to an open distal end of the housing, where the rear end cover has an internal portion comprising a radially inward extending flange;
an actuator having distal end and comprising a longitudinal groove that is in sliding engagement with the radially inward extending flange such that actuator is rotationally fixed relative to the housing;
a drive unit that acts upon the medicament container to advance it from its retracted position to its extended position and to expel its contents through the medicament delivery member; and
a medicament container holder for carrying the medicament container as it is advanced, the medicament container holder having a proximal end that comprises a support surface and is configured with a through hole through which the medicament delivery member extends and a distal end opposite the proximal end; and
a holding member releasably connected to the drive unit and attached to the medicament container holder, where the drive unit exerts a biasing force that moves the holding member proximally when the holding member is attached to the drive unit,
wherein the holding member comprises, at its proximal end, a biasing element having a proximal end surface that engages with and biases the distal end surface of the radially extending flange, where the drive unit biases the biasing element proximally so as to bias the medicament container in a proximal direction within the medicament container holder such that the medicament container abuts the support surface so that the medicament container and the medicament container holder are axially fixed relative to each other,
wherein during medicament delivery member penetration the biasing element dampens the biasing force of the drive unit exerted upon the distal end surface of the medicament container to prevent breakage of the medicament container, and
wherein the biasing element comprises a resilient structure in the form of a tubular wall provided with slots extending in the generally circumferential direction.

2. The medicament delivery device according to claim 1 , wherein the tubular wall is arranged with a first set of slots, where each slot extends a part of the circumference of the tubular wall, forming a bridge between each successive slot.

3. The medicament delivery device according to claim 2 , wherein the tubular wall further is provided with second set of slots that each extend a part of the circumference of the tubular wall, forming a bridge between each successive slot, where the second set of slots is placed offset to the first set of slots as seen in a longitudinal direction.

4. The medicament delivery device according to claim 3 , wherein the bridges of the first set of slots are placed offset in relation to the bridges of the second set of slots as seen in a circumferential direction.

5. The medicament delivery device according to claim 1 , wherein said biasing element is arranged integrated in said holding member.

6. The medicament delivery device according to claim 1 , wherein said biasing element is arranged as a separate component.

7. The medicament delivery device according to claim 1 , wherein said biasing element is made of a resilient material.

8. The medicament delivery device according to claim 1 , wherein said holding element is arranged with a number of distally directed arms having free ends that are arranged with first engagement elements that releasably engage corresponding second engagement elements of a plunger rod of said drive unit.

9. The medicament delivery device according to claim 8 , wherein said first engagement elements comprise ledges and wherein said second engagement elements comprise recesses.

10. The medicament delivery device according to claim 8 , wherein said drive unit comprises a movable actuator sleeve arranged radially outside said arms of said holding element, for releasably holding said arms in an engagement with said plunger rod.

11. The medicament delivery device according to claim 8 , wherein the actuator is arranged with third engagement elements arranged to releasably engage said second engagement elements of said plunger rod.

12. The medicament delivery device according to claim 11 , wherein said actuator is operably connected to an activator for activating said drive unit.

13. The medicament delivery device according to claim 12 , wherein said activator comprises a medicament delivery member guard extending from a proximal end of the medicament delivery device and movable from an initial position to an activation position.

14. An assembly for advancing a medicament container within a housing of a medicament delivery device comprising:
a medicament container movable between a retracted position and an extended position and coaxial to a longitudinal axis of the housing, where the medicament container comprises a syringe barrel having a radially extending flange having a distal end surface;
a rear end cover configured to connect to an open distal end of the housing such that the rear end cover is axially fixed relative to the longitudinal axis, where when the rear end cover is connected to the housing the assembly is attached within the housing, and where the rear end cover has an internal portion comprising a radially inward extending flange;
an actuator having distal end and comprising a longitudinal groove that is in sliding engagement with the radially inward extending flange such that when the rear end cover is attached to the housing the actuator is rotationally fixed relative to the housing;
a medicament container holder for carrying the medicament container between the retracted position and the extended position, where the medicament container holder comprises a proximal end having a support surface;
a drive unit operatively engaged with the medicament container holder to move the medicament container from the retracted position to the extended position; and

a holding member releasably connected to the drive unit and attached to the medicament container holder, where the holding member comprises a biasing element having a proximal end surface that engages with and biases the distal end surface of the radially extending flange, where the drive unit biases the biasing element proximally such that the medicament container is biased in a proximal direction to cause the medicament container holder to abut the support surface,
wherein during medicament delivery member penetration the biasing element dampens the biasing force of the drive unit exerted upon the distal end surface of the medicament container to prevent breakage of the medicament container, and
wherein the biasing element comprises a resilient structure in the form of a tubular wall provided with slots extending in the generally circumferential direction.

15. The assembly according to claim 14 , wherein the tubular wall is arranged with a first set of slots, where each slot extends a part of the circumference of the tubular wall, forming a bridge between each successive slot.

Assignees

• Carebay Europe Ltd
• Shl Medical Ag

Inventors

• André Erika
• Scanlon Gerard

Classifications

• A61M5/2033 Primary

  Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287) · CPC title

• A61M5/3204 Primary

  Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices · CPC title

• A61M2005/3247

  Means to impede repositioning of protection sleeve from needle covering to needle uncovering position · CPC title

• A61M2005/2477

  comprising means to reduce play of ampoule within ampoule holder, e.g. springs · CPC title

• A61M2205/581

  by audible feedback · CPC title