Analysis map generating device that analyzes a rotating excitation wave in biological tissue

Patent metadata

Field	Value
Publication number	US-11547340-B2
Application number	US-201816499539-A
Country	US
Kind code	B2
Filing date	Mar 20, 2018
Priority date	Mar 31, 2017
Publication date	Jan 10, 2023
Grant date	Jan 10, 2023

Abstract

An aspect of the present disclosure calculates a phase variance value indicating a degree of variance of a phase in a surrounding of each position in a biological tissue, based on phase values of excitation wave at respective positions in the biological tissue that acts in response to excitation caused by propagation of the excitation wave in the tissue, and generates an analysis map, based on a time series of at least part of the phase variance values at the respective positions. Since the phase variance value indicates the degree of variance of the phase in the surrounding, a position having a large degree of variance of the phase in the surrounding may be specified as a rotation center of rotating excitation wave.

First claim

The invention claimed is:

1. An analysis map generating device configured to generate an analysis map used to make an analysis with regard to rotating excitation wave in a biological tissue that acts in response to excitation caused by propagation of excitation wave in the tissue, the analysis map generating device comprising:
a processor programmed to:
calculate a phase variance value indicating a degree of variance of a phase in a surrounding of each position in the biological tissue, based on phase values of the excitation wave at respective positions in the biological tissue; and
generate the analysis map, based on (i) a time series of at least part of the phase variance values at the respective positions, and (ii) a determination of whether the at least part of the phase variance values are equal to or greater than a predetermined value.

2. The analysis map generating device according to claim 1 ,
wherein the processor is programmed to generate the analysis map, based on time accumulation of the phase variance values at the respective positions.

3. The analysis map generating device according to claim 1 ,
wherein the processor is programmed to generate the analysis map, based on time accumulation of phase variance values that are equal to or larger than the predetermined value, among the phase variance values at the respective positions.

4. The analysis map generating device according to claim 1 ,
wherein the processor is programmed to generate the analysis map, based on time accumulation of binarized values obtained by binarizing the phase variance values at the respective positions by using the predetermined value.

5. The analysis map generating device according to claim 1 ,
wherein the processor is programmed to generate the analysis map, based on time accumulation of phase variance values that are smaller than the predetermined value, among the phase variance values at the respective positions.

6. The analysis map generating device according to claim 1 ,
wherein the phase variance value is calculated according to Expression (1) given below:

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7. A non-transitory computer readable storage medium that stores a program that causes a computer to serve as an analysis map generating device configured to generate an analysis map used to make an analysis with regard to rotating excitation wave in a biological tissue that acts in response to excitation caused by propagation of excitation wave in the tissue, the program comprising:
a step of calculating a phase variance value indicating a degree of variance of a phase in a surrounding of each position in the biological tissue, based on phase values of the excitation wave at respective positions in the biological tissue; and
a step of generating the analysis map, based on (i) a time series of at least part of the phase variance values at the respective positions, and (ii) a determination of whether the at least part of the phase variance values are equal to or greater than a predetermined value.

Assignees

• Univ Tokyo

Inventors

• Sakuma Ichiro
• Tomii Naoki
• Seno Hiroshi
• Honjo Haruo
• Yamazaki Masatoshi

Classifications

• A61B2576/023

  for the heart · CPC title

• A61B5/0044

  for the heart · CPC title

• G16H30/40 Primary

  for processing medical images, e.g. editing · CPC title

• A61B5/327 Primary

  Generation of artificial ECG signals based on measured signals, e.g. to compensate for missing leads · CPC title

• A61B5/742

  using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339) · CPC title