Medical imaging device, method, and use

Patent metadata

Field	Value
Publication number	US-11547290-B2
Application number	US-202016949751-A
Country	US
Kind code	B2
Filing date	Nov 12, 2020
Priority date	Nov 13, 2019
Publication date	Jan 10, 2023
Grant date	Jan 10, 2023

Abstract

A medical imaging device, comprising a illumination unit, can be configured to illuminate a tissue area with light from a first spectral range, comprising a range of visible wavelengths, and with light from a second spectral range, which is different from the first spectral range, an imaging unit, configured to detect light from the first spectral range and to generate a first image of the tissue area on the basis of the detected light from the first spectral range and furthermore configured to detect light from the second spectral range and to generate a second image of the tissue area on the basis of the detected light from the second spectral range, and a superposition unit, configured to generate a superimposed image on the basis of the first and second image in such a way that, in the superimposed image, on the basis of a visual highlighting, it is possible to identify whether and where the tissue area comprises highlight regions which are characterized by an increased emission of light from the second spectral range in comparison to other regions of the tissue area. The document furthermore relates to a method for image-based support for a medical intervention, and to a use of an imaging device in such a method.

First claim

The invention claimed is:

1. A medical imaging device, comprising:
an illumination unit configured to illuminate a middle-ear tissue area with light from a first spectral range, comprising a range of visible wavelengths, and with light from a second spectral range, which is different from the first spectral range;
an imaging unit configured to detect light from the first spectral range and to generate a first image of the middle-ear tissue area based on the detected light from the first spectral range, wherein the first spectral range includes at least one subrange of visible wavelengths greater than 450 nm, and wherein the imaging unit is furthermore configured to detect light from the second spectral range and to generate a second image of the middle-ear tissue area based on the detected light from the second spectral range, wherein the second spectral range includes at least one subrange of wavelengths between 350 nm and 500 nm, and wherein the second spectral range omits at least one subrange of wavelengths smaller than 380 nm; and
a superposition unit configured to generate a superimposed image using on the first and second image, wherein the superimposed image, on the basis of includes a visual highlighting, to identify whether and where the middle-ear tissue area comprises one or more highlighted regions including cholesteatoma tissue, wherein the one or more highlighted regions including cholesteatoma tissue include an increased emission of light from the second spectral range in comparison to other regions of the middle-ear tissue area including bone tissue to differentiate the cholesteatoma tissue from the bone tissue.

2. The medical imaging device according to claim 1 , wherein the second spectral range omits at least one subrange of wavelengths greater than 450 nm.

3. The medical imaging device according to claim 1 , wherein the illumination unit is configured for a sequential illumination of the middle-ear tissue area with light from the first and second spectral range, and/or wherein the imaging unit is configured for a sequential generation of the first and second image.

4. The medical imaging device according to claim 1 , wherein the illumination unit is configured for a simultaneous illumination of the middle-ear tissue area with light from the first and second spectral range, and/or wherein the imaging unit is configured for a simultaneous generation of the first and second image, wherein the first and second image are spatially separated by means of at least one optical filter.

5. The medical imaging device according to claim 1 , wherein the superposition unit is configured to generate the superimposed image by at least one of alternate generation, display, hiding, or refreshing of the first and second image, wherein a frequency of at least one of the alternation between the first and second image, the refreshing of the first or second image, generation of the first or second image, display of the first or second image, hiding of the first or second image is at least 30 Hz.

6. The medical imaging device according to claim 1 , wherein the medical imaging device is or comprises an ENT microscope, a surgical microscope, or an endoscope.

7. The medical imaging device according to claim 1 , furthermore comprising:
a detection unit configured to detect a first pixel dataset, corresponding to the first image generated by the imaging unit, and a second pixel dataset, corresponding to the second image generated by the imaging unit, wherein the detection unit includes at least one image sensor configured for spatially resolved detection of at least one of the first pixel dataset or the second pixel dataset, and wherein the superposition unit is or comprises an image processing unit which is configured to generate a third pixel dataset, corresponding to the superimposed image, based the first and second pixel dataset.

8. The medical imaging device according to claim 7 , wherein the detection unit is configured for a repeated detection of images with a repetition frequency of at least 30 Hz, preferably at least 60 Hz, and/or wherein the image processing unit is configured to generate the third pixel dataset with a latency of less than 100 ms.

9. The medical imaging device according to claim 7 , wherein the detection unit comprises an image sensor with a plurality of pixel groups and each of the pixel groups comprises at least one first pixel, configured to detect light from the first spectral range, and at least one second pixel, configured to detect light from the second spectral range.

10. The medical imaging device according to claim 9 , wherein the pixel groups are arranged, in a coplanar manner, in multiple rows of multiple pixel groups per row, in particular on a joint sensor chip.

11. The medical imaging device according to claim 7 , wherein the image processing unit is configured to generate the visual highlighting by at least one of: means of a threshold value for the second image, means of a segmentation of the second image, means of a color space transformation, a feature extraction, an object classification, a pattern recognition, a principal component analysis, or an independent component analysis.

12. The medical imaging device according to claim 1 , wherein the first spectral range omits at least one subrange of the second spectral range.

13. A method for providing image-based support for a medical intervention comprising the following steps:
illuminating a middle-ear tissue area with light from a first spectral range, comprising a range of visible wavelengths, and with light from a second spectral range, which is different from the first spectral range wherein the first spectral range includes at least one subrange of visible wavelengths greater than 450 nm, wherein the second spectral range includes at least one subrange of wavelengths between 350 nm and 500 nm, and wherein the second spectral range omits at least one subrange of wavelengths smaller than 380 nm;
detecting light from the first spectral range and from the second spectral range;
generating a first image of the middle-ear tissue area based on the detected light from the first spectral range and a second image of the middle-ear tissue area based on the detected light from the second spectral range;
generating a superimposed image from the first and second image in such a way that, in the superimposed image, on the basis of a visual highlighting, it is possible to identify whether and where the middle-ear tissue area comprises highlight regions which are characterized by an increased emission of light from the second spectral range in comparison to other regions of the tissue area, and
examining the middle-ear tissue to differentiate cholesteatoma tissue from bone tissue.

14. The method according to claim 13 , wherein the first spectral range omits at least one subrange of the second spectral range.

Assignees

• Fraunhofer Ges Forschung

Inventors

• Wisotzky Eric
• Eisert Peter
• Hilsmann Anna

Classifications

• A61B1/227 Primary

  for ears, i.e. otoscopes · CPC title

• A61B1/0005

  combining images e.g. side-by-side, superimposed or tiled · CPC title

• A61B1/0638

  providing two or more wavelengths · CPC title

• H04N5/265 Primary

  Mixing · CPC title

• A61B1/000094

  extracting biological structures · CPC title