Compounds for the treatment of kinase-dependent disorders

US11542259B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11542259-B2
Application numberUS-201916964330-A
CountryUS
Kind codeB2
Filing dateJan 25, 2019
Priority dateJan 26, 2018
Publication dateJan 3, 2023
Grant dateJan 3, 2023

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Disclosed herein are compounds of formula I. Compounds of formula I inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

First claim

Opening claim text (preview).

The invention claimed is: 1. A compound which is: or a pharmaceutically acceptable salt thereof. 2. A compound which is 1-N′-(4-fluorophenyl)-1-N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]cyclopropane-1,1-dicarboxamide or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • Antineoplastic agents · CPC title

  • linked by a chain containing hetero atoms as chain links · CPC title

  • directly linked by a ring-member-to-ring-member bond · CPC title

  • linked by a chain containing hetero atoms as chain links · CPC title

  • Quinolines; Isoquinolines · CPC title

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What does patent US11542259B2 cover?
Disclosed herein are compounds of formula I. Compounds of formula I inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides m…
Who is the assignee on this patent?
Exelixis Inc
What technology area does this patent fall under?
Primary CPC classification C07D215/22. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jan 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).