Self-folding sub-centimeter structures

Patent metadata

Field	Value
Publication number	US-11535510-B2
Application number	US-201113643944-A
Country	US
Kind code	B2
Filing date	Apr 27, 2011
Priority date	Apr 27, 2010
Publication date	Dec 27, 2022
Grant date	Dec 27, 2022

Abstract

A sub-centimeter structure includes a first structural component, a second structural component arranged proximate the first structural component, and a joint connecting the first and second structural components. The joint includes a material that has a first phase that is substantially rigid to hold the first and second structural components in a substantially rigid configuration while the material is in the first phase. The material of the joint has a second phase such that the joint is at least partially fluid to allow the first and second structural components to move relative to each other while the material is in the second phase. The joint interacts with the first and second structural components while the material is in the second phase to cause the first and second structural components to move relative to each other. And, the first and second structural components include a polymer.

First claim

We claim:

1. A sub-centimeter and self-assembled structure, comprising:
a plurality of structural components;
a plurality of joint components each connecting an adjacent pair of said plurality of structural components; and
a plurality of locking structures each formed on an edge of at least one of said plurality of structural components,
wherein said plurality of joint components each comprise a material that has a first phase that is substantially rigid to hold said plurality of structural components in a substantially rigid configuration while said material is in said first phase, and said material has a second phase such that said plurality of joint components are at least partially fluid to allow said plurality of structural components to move relative to each other while said material is in said second phase so as to effect self-assembly into a folded configuration to form a sub-centimeter and self- assembled enclosing structure,
wherein said plurality of locking structures are arranged such that said plurality of structural components lock together via said plurality of locking structures to form said sub-centimeter and self-assembled enclosing structure,
wherein said sub-centimeter and self-assembled enclosing structure is formed at least partially from a biodegradable polymer,
wherein said plurality of structural components comprise a biocompatible polymer material selected from the list of materials consisting of SU 8 , poly(propylene), Poly(esters), Polyimides, and Gelatin,
wherein said plurality of joint components comprise a biocompatible polymer material selected from the list of materials consisting of Gelatin, poly(caprolactone), and chitosan, and the material of said plurality of joint components is retained within said sub-centimeter and self-assembled enclosing structure, and
wherein said plurality of locking structures comprise a biocompatible polymer material selected from the list of materials consisting of Gelatin, Poly(caprolactone), chitosan, alginate, and poly(NIPAAm), and said material of said plurality of locking structures is provided at edges of said plurality of structural components such that when at least two of said plurality of structural components are brought next to each other to form the sub-centimeter and self-assembled enclosing structure, the material on opposite edges overlap to form overlapping edges of the sub-centimeter and self-assembled enclosing structure.

2. A sub-centimeter and self-assembled structure according to claim 1 , wherein said joint components interact with said plurality of structural components due to a surface tension of said material of said plurality of joint components.

3. A sub-centimeter and self-assembled enclosing structure according to claim 1 , wherein said sub-centimeter and self-assembled enclosing structure has a maximum dimension of at least 10 nm and less than 10 mm.

4. A sub-centimeter and self-assembled enclosing structure according to claim 1 , wherein said sub-centimeter and self-assembled enclosing structure has a maximum dimension of at least 10 nm and less than 1 mm.

5. A sub-centimeter and self-assembled enclosing structure according to claim 1 , wherein said sub-centimeter and self-assembled enclosing structure is substantially transparent to visible light substantially across the visible region of the electromagnetic spectrum.

6. A sub-centimeter and self-assembled enclosing structure according to claim 1 , wherein said plurality of joint components comprise a biodegradable material.

7. A sub-centimeter and self-assembled enclosing structure according to claim 1 , wherein at least one of said plurality of structural components defines at least one through hole to permit fluids to pass therethrough.

8. A sub-centimeter and self-assembled enclosing structure according to claim 1 , further comprising a surface material disposed on at least one of said plurality of structural components to at least one of provide or facilitate interactions with a local environment of said sub-centimeter and self-assembled enclosing structure.

9. A sub-centimeter and self-assembled enclosing structure according to claim 8 , wherein said surface material comprises a hydrogel.

10. A sub-centimeter and self-assembled enclosing structure according to claim 1 , further comprising at least one of an electronic, an electro-optical or an optical component.

11. An array comprising a plurality of sub-centimeter and self- assembled structures, wherein each of said plurality of sub-centimeter and self-assembled structures comprises:
a plurality of structural components;
a plurality of joint components each connecting an adjacent pair of said plurality of structural components; and
a plurality of locking structures each formed on an edge of at least one of said plurality of structural components,
wherein said plurality of joint components each comprise a material that has a first phase that is substantially rigid to hold said plurality of structural components in a substantially rigid configuration while said material is in said first phase, and said material has a second phase such that said plurality of joint components are at least partially fluid to allow said plurality of structural components to move relative to each other while said material is in said second phase so as to effect self-assembly into a folded configuration to form a sub-centimeter and self- assembled enclosing structure,
wherein said plurality of locking structures are arranged such that said plurality of structural components lock together via said plurality of locking structures to form said sub- centimeter and self-assembled enclosing structure,
wherein said sub-centimeter and self-assembled enclosing structure is formed at least partially from a biodegradable polymer,
wherein said plurality of structural components comprise a biocompatible polymer material selected from the list of materials consisting of SU 8 , poly(propylene), Poly(esters), Polyimides, and Gelatin,
wherein said plurality of joint components comprise a biocompatible polymer material selected from the list of materials consisting of Gelatin, poly(caprolactone), and chitosan, and the material of said plurality of joint components is retained within said sub-centimeter and self-assembled enclosing structure, and
wherein said plurality of locking structures comprise a biocompatible polymer material selected from the list of materials consisting of Gelatin, Poly(caprolactone), chitosan, alginate, and poly(NIPAAm), and said material of said plurality of locking structures is provided at edges of said plurality of structural components such that when at least two of said plurality of structural components are brought next to each other to form the sub-centimeter and self-assembled enclosing structure, the material on opposite edges overlap to form overlapping edges of the sub-centimeter and self-assembled enclosing structure.

12. An array according to claim 11 , further comprising a substrate, wherein said plurality sub-centimeter and self-assembled structures are attached to said substrate.

13. An array according to claim 11 , wherein each of said plurality of sub-centimeter and self-assembled structures has an open end for receiving material to be loaded into said array.

14. An array according to claim 11 , wherein each of said plurality of sub-centimeter and self-assembled structures has a plurality of porous sides to allow fluid flow there through.

15. A composition comprising a plurality of sub-centimeter and self-assembled structures, wherein each of said plurality of sub-centimeter and self-assembled structures com

Assignees

• Gracias David H
• Azam Anum
• Univ Johns Hopkins

Inventors

• Gracias David H
• Azam Anum

Classifications

• Y10T428/1397

  Single layer [continuous layer] · CPC title

• Y10T428/19

  Sheets or webs edge spliced or joined · CPC title

• B81B2201/06

  Bio-MEMS · CPC title

• B81C1/00007 Primary

  Assembling automatically hinged components, i.e. self-assembly processes (self-assembly mechanisms B81B7/0003) · CPC title

• B81B2203/0315

  Cavities · CPC title