Method and apparatus for measuring and inactivating pathogens using magnetizable devices in a body

Patent metadata

Field	Value
Publication number	US-11534771-B2
Application number	US-202016900414-A
Country	US
Kind code	B2
Filing date	Jun 12, 2020
Priority date	May 24, 2020
Publication date	Dec 27, 2022
Grant date	Dec 27, 2022

Abstract

An apparatus and method collect and deactivate pathogens (for example, coronaviruses) within a magnetic particle in order to reduce the number of active pathogens in a body.

First claim

The invention claimed is:

1. An apparatus for damaging, or destroying at least one pathogen in a body, the apparatus comprising:
at least one magnetic actuator external to a body, and
at least one device containing at least one fillable section and at least one magnetizable material,
wherein the at least one device is configured to draw a pathogen into the fillable section of the device and damage, or destroy the pathogen within the fillable section of the device,
wherein the device is configured to destroy or damage the pathogen within the at least one fillable section of the device by shear or other mechanical forces, the forces actuated by magnetic or electromagnetic radiation emitted by the at least one electromagnetic actuator external to the body,
wherein the at least one device is configured to be delivered into the body orally, by inhalation, or by intravenous injection,
wherein the device is configured to rotate to draw the pathogen into the fillable section of the device by rotation created suction generated at least in part by actuation of the magnetizable material under the influence of a magnetic field generated by the magnetic actuator to rotate the device.

2. The apparatus of claim 1 , wherein the pathogen drawn within the fillable section of the device is damaged or destroyed or damaged by heat generated by the magnetizable material of the device, wherein the heat is generated by electromagnetic radiation emitted by an electromagnetic actuator or antenna external to the body.

3. The apparatus of claim 1 , wherein the apparatus is further configured to detect the pathogen by changing a magnetic field generated by the magnetic actuator via imaging.

4. The apparatus of claim 1 , wherein a presence or absence of the pathogen in the device is sensed using an electromagnetic actuator or antenna external to the body.

5. The apparatus of claim 1 , wherein the device is biodegradable in the body.

6. The apparatus of claim 1 , wherein the pathogen is a microbe.

7. The apparatus of claim 1 , wherein the pathogen is a cell.

8. The apparatus of claim 1 , wherein the device is magnetically bar-coded.

9. The apparatus of claim 1 , wherein at least part of the device is at least partly toxic to part of the pathogen.

10. The apparatus of claim 1 , wherein at least part of the device is at least partly sensitive to at least part of the pathogen.

11. The apparatus of claim 1 , wherein parts of the device are attracted to each other over a sub-micron distance under magnetic field from an actuator external to a body and thereby mechanically inactivate pathogenic materials.

12. A method of destroying or damaging one or more pathogens in a body, the method comprising:
introducing a device containing magnetizable material and also containing a fillable section into the body and at least one magnetic actuator external to the body;
drawing the pathogen into the fillable section of the device; and
damaging, or destroying the pathogen in the fillable section of the device,
wherein the pathogen within the fillable section of the device is destroyed or damaged by shear or other mechanical forces, the forces actuated by magnetic or electromagnetic radiation emitted by at least one electromagnetic actuator external to the body,
wherein the at least one device is configured to be introduced orally, by inhalation, or by intravenous injection,
wherein the device is configured to rotate to draw the pathogen into the fillable section of the device by rotation created suction generated at least in part by actuation of the magnetizable material under the influence of a magnetic field generated by the magnetic actuator to rotate the device.

13. The method of claim 12 , wherein the damage or destruction is implemented by rotation of the device.

14. The method of claim 12 , further comprising detecting one or more pathogens by magnetic resonance.

15. The method of claim 12 , wherein the damage or destruction is implemented by heating of one or more sections of the device.

16. The method of claim 12 , wherein the device contains binding sites to increase the effectiveness in damaging or destroying a specific pathogen that binds to those sites.

17. The method of claim 12 , wherein dimensions of the device are more effective in damaging or destroying specific-sized pathogens as compared to damaging or destroying objects that are different in size than the pathogen.

18. The method of claim 12 , wherein the device is selectively localized in specific portions of the body by the external magnetic actuator.

19. The method of claim 12 , where the device is used after a body has been exposed or is suspected to have been exposed to a pathogen in order to prophylactically reduce the likelihood of disease caused at least in part by the pathogen.

Assignees

• Weinberg Medical Physics Inc

Inventors

• Weinberg Irving

Classifications

• A61N2/004

  specially adapted for a specific therapy · CPC title

• B03C2201/22

  characterised by the magnetic field, e.g. its shape or generation · CPC title

• B03C1/288 Primary

  disposed at the outer circumference of a recipient · CPC title

• A61N2/06

  using magnetic fields produced by permanent magnets (A61N2/12 takes precedence) · CPC title

• A61P33/00

  Antiparasitic agents · CPC title