Multiplexed Lateral Flow Assay Device
US-2020378957-A1 · Dec 3, 2020 · US
US11534752B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11534752-B2 |
| Application number | US-202017138419-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 30, 2020 |
| Priority date | Dec 30, 2020 |
| Publication date | Dec 27, 2022 |
| Grant date | Dec 27, 2022 |
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Official abstract text for this publication.
An embodiment includes a sample receiving region, a first diagnostic element that includes one or more colorimetric analysis regions, and a second diagnostic element that includes one or more lateral flow assay analysis regions. The embodiment also includes a first flow path that allows a portion of a liquid deposited at the sample receiving region to flow to the first diagnostic element. The embodiment also includes a second flow path that allows a portion of the liquid deposited at the sample receiving region to flow to the second diagnostic element.
Opening claim text (preview).
What is claimed is: 1. An apparatus comprising: a sample receiving region; a first diagnostic element that includes one or more colorimetric analysis regions; a second diagnostic element that includes one or more lateral flow assay analysis regions; a first distribution substrate comprising a first hydrophilic region and a first hydrophobic region that defines a boundary of the first hydrophilic region, wherein the first hydrophilic region receives liquid deposited at the sample receiving region; and a second distribution substrate comprising a second hydrophilic region that receives a first portion of liquid from the first hydrophilic region and allows the liquid to flow to the first diagnostic element, a third hydrophilic region that receives a second portion of liquid from the first hydrophilic region and is configured to allow the liquid to flow to the second diagnostic element, and a second hydrophobic region that is configured to oppose traversal of liquid from the second hydrophilic region to the third hydrophilic region. 2. The apparatus of claim 1 , further comprising an impermeable housing, wherein the sample receiving region comprises an opening defined by the housing. 3. The apparatus of claim 2 , further comprising a graphical element on the housing, wherein the graphical element is encoded with information associated with the first diagnostic element and the second diagnostic element. 4. The apparatus of claim 1 , wherein the first diagnostic element comprises a sample conveying portion that guides the first portion of the liquid to a colorimetric reacting region. 5. The apparatus of claim 4 , wherein each of the one or more colorimetric analysis regions comprises a first colorimetric reaction area, a second colorimetric reaction area, and a hydrophobic area that at least partially disposed between the first colorimetric reaction area and the second colorimetric reaction area. 6. The apparatus of claim 1 , further comprising a pressure point element facilitating fluid communication between the first hydrophilic region and the first and second diagnostic regions.
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