Neural sleeve for neuromuscular stimulation, sensing and recording

Patent metadata

Field	Value
Publication number	US-11534605-B2
Application number	US-202016877554-A
Country	US
Kind code	B2
Filing date	May 19, 2020
Priority date	Jun 2, 2015
Publication date	Dec 27, 2022
Grant date	Dec 27, 2022

Abstract

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

First claim

The invention claimed is:

1. A device for neuromuscular stimulation, comprising:
an outer reusable sleeve including electrodes; and
an inner disposable sleeve comprising a conductive hydrogel medium in contact with the electrodes of the outer reusable sleeve, the inner disposable sleeve configured to provide a conductive interface between the electrodes of the outer reusable sleeve and the user's skin when the device is worn by the user;
wherein the conductive hydrogel medium comprises a cross-linked alginate polymer or a cross-linked polymeric hydrogel.

2. The device of claim 1 , wherein the conductive hydrogel medium comprises a cross-linked alginate polymer.

3. The device of claim 1 , wherein the reusable sleeve comprises at least two flexible fingers along which the one or more electrodes are located, the flexible fingers extending in the same direction from a first connector, and the conductive hydrogel medium is disposed on each flexible finger.

4. The device of claim 3 , wherein each flexible finger includes a conductive circuit layer and an insulating base layer upon which the conductive circuit layer is laid.

5. The device of claim 4 , wherein each flexible finger includes an insulating cover layer over the conductive circuit layer.

6. The device of claim 1 , wherein each electrode of the electrodes includes concentric rows of teeth about 200 μm to about 300 μm in height.

7. The device of claim 1 , wherein the reusable sleeve comprises:
a rigid shell including two hemicylindrical halves; and
a hinge running parallel to a longitudinal axis of the reusable sleeve and joining the two hemicylindrical halves.

8. The device of claim 1 , wherein the reusable sleeve comprises an accelerometer; and is configured for gesture control of devices.

9. The device of claim 1 , wherein the reusable sleeve contains bladders that can be filled to expand and push the electrodes against skin.

10. The device of claim 1 , wherein the reusable sleeve comprises a compression sleeve fabric on which the electrodes comprise conductive polycellulose or silver/carbon-based ink.

11. The device of claim 10 , further comprising a conductive pathway including an accelerometer.

12. The device of claim 1 , wherein the reusable sleeve comprises a flexible circuit including electrodes connected by electrode traces that (i) house sensors and (ii) the electrode traces are arranged in a zig-zag pattern.

13. The device of claim 12 , wherein the sensors comprise any combination of pressure sensors; strain gauges; accelerometers; a micro-electro-mechanical system (MEMS) including a 3-axis accelerometer and 3-axis magnetometer; a capacitive sensor including a flexible insulating dielectric layer sandwiched between flexible electrodes; a stretch sensor including a material that changes electrical resistance when stretched or strained; a resonant bend sensor including a resistance-inductance-capacitance (RLC) circuit; a sensor including at least one bladder configured to hold a fluid or air; a fiber optic cable and a measurement tool configured to measure a bend in the fiber optic cable based on a frequency or attenuation change in a signal of the fiber optic cable; and a video motion tracking system configured to track a marker of the reusable sleeve.

14. The device of claim 1 , wherein the reusable sleeve comprises conductive fibers and a dry fit material.

15. The device of claim 1 , wherein the reusable sleeve is in the form of a fingerless glove.

16. The device of claim 1 , wherein the electrodes are woven into the reusable sleeve using conductive threads.

17. The device of claim 1 , wherein the reusable sleeve is configured to:
cover both a leg portion and a foot portion of a patient; and
support gait-training.

18. The device of claim 1 , wherein the reusable sleeve comprises a shirt configured to deliver electrical stimulation to a backside of a patient.

19. The device of claim 1 , wherein the electrodes are configured to both deliver electrical simulation and sense a neural signal of a patient.

20. A device for neuromuscular stimulation, comprising:
a reusable sleeve;
electrodes housed within the reusable sleeve; and
an inner disposable sleeve comprising a conductive hydrogel medium in contact with the electrodes, the inner disposable sleeve configured to provide a conductive interface between the electrodes of the reusable sleeve and the user's skin when the device is worn by the user;
wherein each electrode of the electrodes includes concentric rows of teeth about 200 yum to about 300 um in height.

Assignees

• Battelle Memorial Institute

Inventors

• Bouton Chad E
• Sharma Gaurav
• Sweeney Andrew
• Heintz Amy M
• Kute Stephanie
• Annetta Nicholas
• Haubert Thomas D
• Risser Steven M
• Friend Jeffrey
• Bartholomew John
• Thurston Rachel
• Morrow Alexander C
• Brand George
• Ellis Jeffrey
• Mowrer Matthew
• Zaborski Raymond

Classifications

• A61B5/389

  Electromyography [EMG] · CPC title

• A61N1/0452

  Specially adapted for transcutaneous muscle stimulation [TMS] · CPC title

• A61N1/048

  Electrodes characterised by a specific connection between lead and electrode · CPC title

• A61B5/11

  Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb {(A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721)} · CPC title

• A61B5/251

  Means for maintaining electrode contact with the body · CPC title