Pearl culture material and coating composition
US-2020296940-A1 · Sep 24, 2020 · US
US11523592B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11523592-B2 |
| Application number | US-202117225127-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 8, 2021 |
| Priority date | Oct 12, 2018 |
| Publication date | Dec 13, 2022 |
| Grant date | Dec 13, 2022 |
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There are provided a pearl culture material containing at least one selected from the group consisting of a pearl nucleus and a mantle, and the at least one selected from the group consisting of a pearl nucleus and a mantle contains a protein having 10 EU/g or less of an endotoxin amount, a nucleus insertion method, and a pearl culture material composition.
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What is claimed is: 1. A pearl culture material comprising at least one selected from the group consisting of a pearl nucleus and a mantle, wherein the at least one selected from the group consisting of a pearl nucleus and a mantle contains a protein having 10 EU/g or less of an endotoxin amount, and wherein the protein having 10 EU/g or less of an endotoxin amount includes a repeating sequence of a GXY triplet, which may be separated by one or more amino acids, includes one or more RGD motifs, and has a polydispersity of less than 20. 2. The pearl culture material according to claim 1 , wherein a coating amount of the protein in a surface area of the pearl nucleus or the mantle is 20 pg/mm 2 or more. 3. The pearl culture material according to claim 1 , wherein the endotoxin amount is 2.5 EU/g or less. 4. The pearl culture material according to claim 1 , wherein the protein contains at least a part of an amino acid sequence of collagen. 5. The pearl culture material according to claim 4 , wherein the amino acid sequence of the collagen is an amino acid sequence of type I collagen α 1 chain. 6. The pearl culture material according to claim 1 , wherein the protein has a weight-average molecular weight of 30 kDa to 200 kDa, which is determined by gel permeation chromatography. 7. The pearl culture material according to claim 1 , wherein the protein includes a protein derived from a genetically recombinant yeast. 8. A method of inserting a pearl nucleus into a pearl sag of a mother pearl oyster from which a pearl has been taken out, using the pearl culture material according to claim 1 . 9. A method of producing a pearl using a mother pearl oyster which is subjected to nucleus insertion by the method according to claim 8 .
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