Systems, devices and methods for making and expressing foam used in medical procedures

Patent metadata

Field	Value
Publication number	US-11517527-B2
Application number	US-201816180482-A
Country	US
Kind code	B2
Filing date	Nov 5, 2018
Priority date	Nov 5, 2018
Publication date	Dec 6, 2022
Grant date	Dec 6, 2022

Abstract

A medical device for making foam includes a syringe having a plunger for dispensing a liquid from a liquid dispensing port, and a mixing chamber including a mixing chamber inlet, a mixing chamber outlet, a liquid flow channel extending between the mixing chamber inlet and the mixing chamber outlet, and a gas inlet channel that intersects with the liquid flow channel. The system has a gas cartridge containing the gas, a first gas conduit connected with the syringe, and a second gas conduit connected with the gas inlet channel. An actuator is coupled with the gas cartridge for releasing the gas into the first and second gas conduits. The released gas in the first gas conduit forces the plunger toward the liquid dispensing port for dispensing the liquid from the liquid dispensing port and into the liquid flow channel while the released gas in the second gas conduit flows into the gas inlet channel of the mixing chamber for mixing with the liquid in the liquid flow channel.

First claim

What is claimed is:

1. A medical device for making foam comprising:
a syringe including a plunger for dispensing a liquid from a liquid dispensing port;
a mixing chamber including a mixing chamber inlet in fluid communication with said liquid dispensing port, a mixing chamber outlet spaced from said mixing chamber inlet, a liquid flow channel extending between said mixing chamber inlet and said mixing chamber outlet, and a gas inlet channel that intersects with said liquid flow channel for mixing a gas with said liquid dispensed from said liquid dispensing port;
a gas cartridge containing said gas;
a first gas conduit having a first end connected with said gas cartridge and a second end connected with said syringe;
a second gas conduit having a first end connected with said gas cartridge and a second end connected with said gas inlet channel of said mixing chamber;
an actuator coupled with said gas cartridge for selectively releasing said gas from said gas cartridge for flowing into said first and second gas conduits, wherein said released gas in said first gas conduit forces said plunger toward said liquid dispensing port for dispensing said liquid from said liquid dispensing port and into said liquid flow channel while said released gas in said second gas conduit flows into said gas inlet channel of said mixing chamber for mixing with said liquid in said liquid flow channel.

2. The medical device as claimed in claim 1 , further comprising a check valve disposed between said liquid dispensing port and said mixing chamber inlet that allows said liquid to flow in only one direction from said liquid dispensing port to said mixing chamber inlet while preventing said gas in said gas inlet channel from passing through said check valve.

3. The medical device as claimed in claim 1 , further comprising a foaming chamber including a foaming chamber inlet in fluid communication with said mixing chamber outlet, a foaming chamber outlet, and a porous material disposed within said foaming chamber, wherein said porous material has a tortuous path configured to generate foam as the mixture of said liquid and said gas passes through said porous material.

4. The medical device as claimed in claim 3 , wherein said porous material in said foaming chamber has a porosity of about 25-40%.

5. The medical device as claimed in claim 1 , further comprising at least one regulator for regulating pressure levels of said gas flowing through said respective first and second gas conduits, wherein said gas in said first gas conduit and said gas in said second gas conduit have different pressure levels.

6. The medical device as claimed in claim 1 , wherein said gas in said gas cartridge is pressurized gas having a pressure level of about 45-65 pounds per square inch, and wherein said pressurized gas is selected from the group of gasses consisting of air, carbon dioxide and nitrogen.

7. The medical device as claimed in claim 1 , further comprising:
an end cap secured over a first end of said syringe, wherein said end cap forms an air-tight connection with the first end of said syringe;
said end cap having a gas inlet port;
said first gas conduit being connected with said gas inlet port of said end cap.

8. The medical device as claimed in claim 1 , wherein said liquid flow channel has an inner diameter that is about 25-30 times larger than an inner diameter of said gas inlet channel.

9. A medical device for making foam comprising:
a syringe including a syringe barrel having a first end, a second end, and a liquid dispensing port located at the second end of said syringe barrel;
a liquid disposed in said syringe barrel;
a plunger disposed within said syringe barrel and being moveable toward said second end of said syringe barrel for dispensing said liquid from said liquid dispensing port;
a mixing chamber comprising
a mixing chamber inlet in fluid communication with said liquid dispensing port,
a mixing chamber outlet spaced from said mixing chamber inlet,
a liquid flow channel extending between said mixing chamber inlet and said mixing chamber outlet, and
a gas inlet channel that intersects with said liquid flow channel;

a check valve disposed between said liquid dispensing port and said mixing chamber inlet that allows said liquid to flow in only one direction from said liquid dispensing port to said mixing chamber inlet;
a gas source including a first gas conduit in fluid communication with said first end of said syringe barrel and a second gas conduit in fluid communication with said gas inlet channel of said mixing chamber;
an actuator coupled with said gas source for simultaneously releasing gas from said gas source into said first and second gas conduits, wherein said released gas in said first gas conduit forces said plunger toward said second end of said syringe barrel for dispensing said liquid from said liquid dispensing port and into said liquid flow channel while said released gas in said second gas conduit flows through said gas inlet channel of said mixing chamber for mixing with said liquid in said liquid flow channel;
a foaming chamber comprising
a foaming chamber inlet in fluid communication with said mixing chamber outlet,
a foaming chamber outlet, and
a porous material disposed within said foaming chamber, wherein the mixture of said liquid and said gas passes through said porous material disposed within said foaming chamber for generating foam that is dispensed from said foaming chamber outlet.

10. The medical device as claimed in claim 9 , wherein said liquid disposed in said syringe barrel comprises a surfactant.

11. The medical device as claimed in claim 9 , further comprising:
an end cap secured over the first end of said syringe barrel;
said end cap having a gas inlet port;
said first gas conduit being connected with said gas inlet port of said end cap.

12. The medical device as claimed in claim 9 , wherein said liquid flow channel has an inner diameter that is larger than an inner diameter of said gas inlet channel.

13. The medical device as claimed in claim 12 , wherein the inner diameter of said liquid flow channel is about 25-30 times larger than the inner diameter of said gas inlet channel.

14. The medical device as claimed in claim 9 , further comprising:
at least one regulator for controlling a pressure level of said gas in said first gas conduit and said second gas conduit, wherein said gas in said first conduit and said gas in said second gas conduit have different pressure levels.

15. The medical device as claimed in claim 9 , wherein said gas in said gas source is pressurized gas having a pressure level of about 45-65 pounds per square inch, and wherein said pressurized gas is selected from the group of gasses consisting of air, carbon dioxide and nitrogen.

16. The medical device as claimed in claim 9 , wherein said porous material in said foaming chamber has a porosity of about 25-40%.

17. The medical device as claimed in claim 9 , further comprising a foam collection receptacle connected with said foam chamber outlet for collecting foam generated within said foam chamber.

18. A method of making foam used for sealing tissues using the medical device of claim 1 comprising:
obtaining a container holding a liquid;
directing a first stream of a gas toward said container for dispensing a stream of said liquid from said container;
simultaneously with directing said first stream of said gas toward said container, directing a second stream of said gas into said dispensed stream of said liquid for generating a liquid and gas

Assignees

• Ethicon Inc

Inventors

• Smith Nicole
• Cardinale Michael

Classifications

• B01F25/4522

  the components being pressed through porous bodies, e.g. flat plates, blocks or cylinders, which obstruct the whole diameter of the tube (B01F25/45243 takes precedence) · CPC title

• A61B2017/00893

  pharmaceutically effective · CPC title

• B01F23/235

  for making foam · CPC title

• A61B17/12109

  in a blood vessel · CPC title

• A61B17/12013

  for use in minimally invasive surgery, e.g. endoscopic surgery · CPC title