Personal care compositions comprising zinc : usnic acid complexes and methods of use

Patent metadata

Field	Value
Publication number	US-11517512-B2
Application number	US-201816631481-A
Country	US
Kind code	B2
Filing date	Jul 16, 2018
Priority date	Jul 19, 2017
Publication date	Dec 6, 2022
Grant date	Dec 6, 2022

Abstract

Disclosed herein are personal care compositions comprising Zn:usnate complexes having a 1:2 zinc to usnate molar ratio. Methods of making and using the compositions are also provided. The personal care compositions may include a cleansing component and an antibacterial component, wherein the antibacterial component comprises Zn:usnate complexes having a 1:2 zinc to usnate molar ratio.

First claim

What is claimed is:

1. A personal care composition comprising a Zn:usnate complex having a 1:2 zinc to usnate molar ratio;
wherein the personal care composition has a pH from about 8.5 to about 12.

2. The personal care composition of claim 1 , wherein said Zn:usnate complex has a solubility of about 13.5 ppm in water at room temperature.

3. The personal care composition of claim 2 , wherein said complex has a minimal inhibitory concentration of about 8 parts per million against S. aureus.

4. The personal care composition according to claim 1 , wherein the personal care composition is a rinse off composition selected from the group consisting of a body wash, a shower gel, a shampoo, a conditioner, a liquid hand or other soap, a dish soap and a facial wash.

5. The personal care composition according to claim 1 , wherein the personal care composition is a leave-on composition selected from the group consisting of a lotion, a cream, an antiperspirant stick, a gel, and an aerosol.

6. The personal care composition of claim 4 , wherein said composition comprises a cleansing component.

7. The personal care composition according to claim 6 , wherein the cleansing component is a liquid soap or a liquid hand soap.

8. The personal care composition according to claim 6 , wherein the cleansing component comprises one or more surfactants.

9. The personal care composition according to claim 8 , wherein the cleansing component comprises at least 8.0 wt % of the one or more surfactants, or at least 9.0 wt % of the one or more surfactants.

10. The personal care composition according to claim 8 , wherein the one or more surfactants comprise a betaine surfactant.

11. The personal care composition of claim 10 , wherein the betaine surfactant is cocoamidopropyl betaine.

12. The personal care composition according to claim 8 , further comprising a foam enhancer, wherein the foam enhancer is cocamide monoethanolamide.

13. A method of treating and/or preventing progression of microorganism induced ailments comprising applying an effective amount of a composition described in claim 1 .

14. A method for cleaning teeth, reducing bacterially-generated biofilm and plaque, reducing gingivitis, and/or inhibiting tooth decay and formation of cavities comprising applying an effective amount of the composition of claim 1 to a tooth surface.

15. A method for controlling microbial growth on a skin surface comprising applying an effective amount of the composition of claim 1 to a skin surface.

16. A method of making the personal care composition of claim 1 , comprising combining usnic acid or usnate and a zinc source in a liquid medium, isolating the complex thus formed in solid form, and combining the zinc:usnate complex with a personal care composition.

17. A personal care composition comprising:
a Zn:usnate complex having a 1:2 zinc to usnate molar ratio,
wherein the personal care composition is a bar soap.

18. The personal care composition of claim 17 , comprising:
at least one cleanser selected from soap and a first surfactant; and
at least one taurate surfactant selected from a salt of a fatty acid amide of taurine, a salt of a fatty acid amide of N-methyl taurine, and combinations thereof, wherein the taurate surfactant is different from the first surfactant.

Assignees

• Colgate Palmolive Co

Inventors

• Jaracz Stanislav
• Pan Long
• Sambanthamoorthy Karthik
• Mao Junhong
• Fan Aixing

Classifications

• A61K8/42

  Amides · CPC title

• A61K8/27 Primary

  Zinc; Compounds thereof · CPC title

• A61Q19/10

  Washing or bathing preparations · CPC title

• A61Q17/00

  Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings · CPC title

• A61K8/49

  containing heterocyclic compounds · CPC title