Probiotic composition making it possible to promote juvenile livestock growth

Patent metadata

Field	Value
Publication number	US-11517029-B2
Application number	US-201716077050-A
Country	US
Kind code	B2
Filing date	Feb 10, 2017
Priority date	Feb 12, 2016
Publication date	Dec 6, 2022
Grant date	Dec 6, 2022

Abstract

The probiotic composition comprises at least one lactic acid bacteria strain, preferably Lactobacillus with intestinal tropism, for use in promoting juvenile growth in livestock, with stimulation of linear growth and/or of IGF-1 level. Exemplary lactic acid bacteria include Lactobacillus plantarum, Lactobacillus fermentum, Lactobacillus casei, Lactobacillus paracasei and Lactobacillus rhamnosus. The strains can be selected in a mouse model. The invention also relates to a probiotic treatment method using this composition.

First claim

The invention claimed is:

1. A method for promoting juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels of animals fed a conventional rearing diet, comprising the administration of a composition or a food comprising at least several grams of a probiotic composition comprising about 10 5 to about 10 12 colony forming units (CFU) Lactobacillus plantarum WJL per gram of probiotic composition to said animal in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

2. The method of claim 1 , said method promoting juvenile livestock post-weaning growth.

3. The method of claim 1 , wherein the animal is post-weaning livestock.

4. The method of claim 1 , said method further comprising measuring serum insulin-like growth factor 1 (IGF-1) levels to determine an increase of IGF-1 levels in treated animals.

5. The method of claim 1 , said method stimulating linear growth.

6. The method of claim 1 , said method increasing levels of IGF-1.

7. A method of promoting juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels of animals fed a conventional rearing diet, comprising the administration of a composition or a food comprising at least several grams of a probiotic composition comprising about 10 5 to about 10 12 colony forming units (CFU) Lactobacillus plantarum WJL per gram of probiotic composition to said animal, wherein the probiotic composition is administered once a day in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

8. A method of promoting juvenile livestock growth with stimulation of the linear growth and/or of the IGF-1 level of animals fed a conventional rearing diet, comprising the administration of a composition or a food comprising at least several grams of a probiotic composition comprising live bacteria in an amount of about 10 5 to about 10 12 colony forming units (CFU) Lactobacillus plantarum WJL per gram of probiotic composition to said animal in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

9. The method of claim 1 , wherein said probiotic composition is administered at a frequency of once per day to once per week.

10. The method of claim 9 , wherein said probiotic composition is administered at a frequency of once per day for three to five days each week.

11. The method of claim 1 , said method comprising the administration of a composition or a food comprising several grams to several tens of grams of a probiotic composition comprising about 10 5 to about 10 12 CFU Lactobacillus plantarum WJL per gram of probiotic composition to said animal in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

12. The method of claim 7 , said method comprising the administration of a composition or a food comprising several grams to several tens of grams of a probiotic composition comprising about 10 5 to about 10 12 CFU Lactobacillus plantarum WJL per gram of probiotic composition to said animal, wherein the probiotic composition is administered once a day in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

13. The method of claim 8 , said method comprising the administration of a composition or a food comprising several grams to several tens of grams of a probiotic composition comprising live bacteria in an amount of about 10 5 to about 10 12 CFU Lactobacillus plantarum WJL per gram of probiotic composition to said animal in an amount that promotes juvenile livestock growth with stimulation of the linear growth and/or of IGF-1 levels.

Assignees

• Ecole Normale Superieure Lyon
• Centre Nat Rech Scient
• Univ Claude Bernard Lyon

Inventors

• Leulier Francois
• Schwarzer Martin

Classifications

• C12R2001/25

  Lactobacillus plantarum · CPC title

• C12N1/205

  Bacterial isolates · CPC title

• A23K10/18 Primary

  of live microorganisms · CPC title

• C12N1/20

  Bacteria; Culture media therefor · CPC title

• A23K50/80

  for aquatic animals, e.g. fish, crustaceans or molluscs · CPC title