Device and method for antibiotic removal from dairy products

Patent metadata

Field	Value
Publication number	US-11517023-B2
Application number	US-201916564644-A
Country	US
Kind code	B2
Filing date	Sep 9, 2019
Priority date	Sep 9, 2019
Publication date	Dec 6, 2022
Grant date	Dec 6, 2022

Abstract

A method of removing one or more antibiotics from a dairy product, the method involve passing the dairy product comprising an antibiotic in a first amount through a bulk comprising, relative to a total bulk weight, at least 75 wt. % of titanium oxide nanostructures, to provide the dairy product comprising the antibiotic in a second, lesser amount, wherein the nanostructures have lengths at least two-fold in excess of their width and height. Bulk materials useful in this or related methods or applications may have loosely tangled, noodle-like morphologies on sub-100 nm scale, and need not employ graphene and/or polymeric support networks in columns, generally having only titanium oxides without silicon or iron oxides.

First claim

The invention claimed is:

1. A method of removing one or more antibiotics from a first dairy product, the method comprising:
passing the first dairy product comprising an antibiotic in a first amount through a bulk comprising, relative to a total bulk weight, at least 75 wt. % of titanium oxide nanostructures, to provide a treated dairy product comprising the antibiotic in a second amount,
wherein the first amount is greater than the second amount, and
wherein the titanium oxide nanostructures have lengths at least two-fold in excess of their width and height.

2. The method of claim 1 , wherein the titanium oxide nanostructures are nanotubes having an average diameter in a range of from 5 to 200 nm.

3. The method of claim 1 , wherein the titanium oxide nanostructures have a formula
H x Na 2-x Ti 2 O 5 ·(H 2 O),

wherein x≤2.

4. The method of claim 1 , wherein the first dairy product is milk.

5. The method of claim 1 , wherein the first dairy product is eluted in a carrier having a pH in a range of from 5.0 to 8.0.

6. The method of claim 1 , wherein the bulk is present in the form of a stationary phase within a column packed with the bulk.

7. The method of claim 1 , wherein the bulk comprises no more than 5 wt. % of materials aside from titanium oxide, relative to the total bulk weight.

8. The method of claim 1 , wherein the passing occurs at a pressure in a range of from 2 to 20 bar.

9. The method of claim 1 , wherein the first amount of the antibiotic is in a range of from 10 to 1200 ppm.

10. The method of claim 1 , wherein the second amount of the antibiotic, reached immediately after the passing, is no more than 15% of the first amount.

11. The method of claim 1 , wherein the passing comprises removing no more than 5 wt. % of an original amount of non-antibiotic components of the first dairy product.

Assignees

• Univ Imam Abdulrahman Bin Faisal

Inventors

• Kochkar Hafedh
• Alomair Nuhad Abdullah
• Alibilali Reem Khalid
• Aljameel Suhailah Saud

Classifications

• B01J20/041

  Oxides or hydroxides · CPC title

• A23C7/043 Primary

  using chemicals in liquid or solid state, e.g. flocculating, adsorbing or extracting agents (A23C9/146 and A23C9/148 take precedence) · CPC title

• B01J20/28083

  being in the range 2-50 nm, i.e. mesopores · CPC title

• B01J20/28007

  with size in the range 1-100 nanometers, e.g. nanosized particles, nanofibers, nanotubes, nanowires or the like (carbon nanostructures B01J20/205) · CPC title

• B01J20/06

  comprising oxides or hydroxides of metals not provided for in group B01J20/04 · CPC title