Methods, apparatuses, and systems for inductive heating of foreign metallic implants

Patent metadata

Field	Value
Publication number	US-11510615-B2
Application number	US-201916247276-A
Country	US
Kind code	B2
Filing date	Jan 14, 2019
Priority date	Jul 14, 2016
Publication date	Nov 29, 2022
Grant date	Nov 29, 2022

Abstract

Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue. The AMF pulse treatment can be combined with an antibacterial/antimicrobial treatment regimen to reduce the time and/or antibacterial dosage amount needed to remove the biofilm from the metallic implant.

First claim

The invention claimed is:

1. A system to treat a surface of a foreign metallic implant, the system comprising:
one or more external transmitter devices comprising an alternating magnetic field (AMF) transmitter configured to apply one or more AMF pulses to the foreign metallic implant;
one or more acoustic sensors configured to detect one or more acoustic waves having a frequency between 0 Hz and 1000 Hz; and
a control system comprising at least one processor, the control system configured to:
enable the one or more external transmitter devices to apply one or more AMF pulses to the foreign metallic implant with one or more of: (a) a predetermined time period, (b) a predetermined pulse duration, (c) a predetermined pulse repetition frequency, or (d) a predetermined power level; and
receive one or more signals from the one or more sensors.

2. The system of claim 1 , the control system being further configured to determine that the one or more signals indicate that a temperature of the foreign metallic implant is sufficient to disrupt a biofilm matrix on the surface of the foreign metallic implant.

3. The system of claim 1 , the one or more acoustic sensors being configured to detect the one or more acoustic waves emitted from soft tissue adjacent to the foreign metallic implant when the soft tissue is heated to a particular temperature threshold.

4. The system of claim 1 , the one or more acoustic sensors being configured to detect the one or more acoustic waves having a frequency between 500 Hz and 1000 Hz.

5. The system of claim 1 comprising one or more internal temperature sensors embedded into the surface of the foreign metallic implant.

6. The system of claim 1 comprising one or more external optical receiver devices configured to detect photons emitted from one or more thermoluminescent materials embedded into the surface of the foreign metallic implant, the one or more thermoluminescent materials configured to emit the photons upon sensing a temperature greater than a predetermined threshold on the surface of the foreign metallic implant.

7. A foreign metallic implant treatment apparatus comprising:
a housing; and
a plurality of AMF transmitters configured to apply one or more AMF pulses to the foreign metallic implant in three orthogonal directions,
where the plurality of AMF transmitters are configured as pairs situated on opposing sides of the metallic implant in each of a Cartesian x-direction, y-direction, and z-direction.

8. The apparatus of claim 7 , where each of the AMF transmitters in a pair are situated in parallel planes from each other.

9. The apparatus of claim 7 , where at least one of the plurality of AMF transmitter pairs is configured to rotate around the foreign metallic implant and apply the one or more AMF pulses at different positions around the foreign metallic implant.

10. The apparatus of claim 7 , further comprising one or more ferromagnetic materials configured to be movable around the foreign metallic implant.

11. A method of treating a foreign metallic implant, the method comprising:
enabling, by a control system comprising at least one processor, one or more external transmitter devices comprising an AMF transmitter to apply one or more AMF pulses to the foreign metallic implant with one or more of a predetermined time period, a predetermined pulse duration, a predetermined pulse repetition frequency, or a predetermined power level;
receiving, by the control system, one or more signals from one or more acoustic sensors;
determining, by the control system, that the one or more signals indicate heating of the foreign metallic implant; and
enabling, by the control system, an adjusting of at least one of a duration, a frequency, or an amplitude of the one or more AMF pulses based on the one or more signals.

12. The method of claim 11 , comprising receiving, by the control system, one or more signals from one or more internal temperature sensors embedded into a surface of the foreign metallic implant.

13. The method of claim 11 , comprising receiving, by the control system, one or more signals from one or more optical sensors comprising one or more external optical receiver devices to detect photons emitted from one or more thermoluminescent materials embedded into a surface of the foreign metallic implant, the one or more thermoluminescent materials configured to emit the photons upon sensing a temperature greater than a predetermined threshold on the surface of the foreign metallic implant.

14. The method of claim 11 , further comprising:
enabling, by the control system, the one or more external transmitter devices to shut off upon receipt of the one or more signals.

15. The system of claim 1 , wherein the AMF transmitter comprises at least one coil.

16. The system of claim 1 , wherein the AMF transmitter comprises a phased array.

17. The system of claim 15 , where at least one coil comprises one or more of a solenoid coil, a saddle coil, a pancake coil, or combinations thereof.

Assignees

• Univ Texas

Inventors

• Chopra Rajiv
• Greenberg David
• Chatzinoff Yonatan

Classifications

• A61L2103/05

  Living organisms or biological materials · CPC title

• A61L2/04

  Heat (radiation A61L2/08) · CPC title

• A61F2002/30677

  Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body · CPC title

• A61N1/403

  for thermotherapy, e.g. hyperthermia · CPC title

• A61B5/4836

  Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence) · CPC title