Metal alloys for medical devices

Patent metadata

Field	Value
Publication number	US-11504451-B2
Application number	US-202117512174-A
Country	US
Kind code	B2
Filing date	Oct 27, 2021
Priority date	Jun 24, 2014
Publication date	Nov 22, 2022
Grant date	Nov 22, 2022

Abstract

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.

First claim

What is claimed:

1. A method for forming a medical device comprising the steps of:
a) providing a metal alloy; said metal alloy including at least about 55 wt. % of a solid solution of rhenium and molybdenum alloy; said metal alloy including at least about 20 wt. % rhenium and at least about 20 wt. % molybdenum; said metal alloy including about 0.01-35 wt. % of an additional metal additive; said additional metal additive includes i) one or more metals selected from the group consisting of hafnium and technetium, or ii) two or more different metals selected from the group consisting of hafnium, osmium, technetium, vanadium, and titanium; and,
b) forming said metal alloy so as to form at least a portion of said medical device.

2. The method as defined in claim 1 , wherein said metal alloy is in the form of a rod or tube, and further including the steps of:
drawing down said outer cross-sectional area of said rod or tube by a reducing mechanism;
annealing said rod or tube at an annealing temperature in an oxygen reducing environment or inert environment after said rod or tube has been drawn down; and,
cooling said annealed rod or tube.

3. The method as defined in claim 1 , wherein said additional additive includes hafnium, or technetium.

4. The method as defined in claim 1 , wherein said metal alloy has a controlled amount of nitrogen, oxygen and carbon so as to reduce micro-cracking in said metal alloy, a nitrogen content in said metal alloy is less than a combined content of oxygen and carbon in said metal alloy, said metal alloy has an oxygen to nitrogen atomic ratio of at least about 1.2:1, said metal alloy has a carbon to nitrogen atomic ratio of at least about 2:1.

5. The method as defined in claim 1 , wherein said metal alloy includes less than about 0.2 wt. % carbon, less than about 0.1 wt. % oxygen, and less than about 0.001 wt. % nitrogen.

6. The method as defined in claim 1 , wherein said metal alloy includes at least 95 wt. % rhenium and molybdenum and less than about 5 wt. % of said one or more additional metals.

7. The method as defined in claim 1 , wherein said metal alloy has a nitrogen content of less than about 0.001 wt. %, said metal alloy has a carbon content of less than about 0.2 wt. %, has an oxygen content of less than about 0.1 wt. %, said metal alloy has an oxygen to carbon atomic ratio of about 0.2:1 and up to about 50:1, said metal alloy has an oxygen to nitrogen atomic ratio of at least about 1.2:1 and up to about 100:1, said metal alloy has a carbon to nitrogen atomic ratio of at least about 2:1 and up to about 100:1.

8. The method as defined in claim 1 , wherein said metal alloy includes about 45-50 wt. % rhenium and about 50-55 wt. % molybdenum.

9. The method as defined in claim 1 , wherein at least one region of said medical device includes at least one biological agent.

10. The method as defined in claim 1 , wherein at least one region of said medical device includes at least one polymer.

11. The method as defined in claim 9 , wherein at least one region of said medical device includes at least one polymer, at least one said polymer at least partially coats, encapsulates, or combinations thereof, at least one said biological agent.

12. The method as defined in wherein claim 1 , further comprising at least one micro-structure on an outer surface of said medical device.

13. The method as defined in claim 12 , wherein at least one said microstructure is at least partially formed of, includes, or combinations thereof, a material consisting of a polymer, an agent, or combinations thereof.

14. The method as defined in claim 1 , wherein said metal alloy includes one or more secondary metals, said secondary metals selected from the group consisting of aluminum, antimony, barium, cadmium, calcium, chromium, cobalt, copper, gallium, germanium, gold, indium, iridium, iron, lead, magnesium, manganese, nickel, osmium, palladium, platinum, rare earth metals, rhodium, ruthenium, scandium, selenium, silicon, silver, strontium, tantalum, tellurium, tin, yttrium, and zinc.

15. The method as defined in claim 14 , wherein said secondary metal includes chromium.

Assignees

• Mirus Llc

Inventors

• Roth Noah
• Patel Udayan

Classifications

• Y10S29/011

  Method or apparatus with drawing · CPC title

• Y10S72/70

  Deforming specified alloys or uncommon metal or bimetallic work · CPC title

• Y10S29/025

  Method or apparatus with particular material · CPC title

• B21C1/00

  Manufacture of metal sheets, wire, rods, tubes or like semi-manufactured products by drawing · CPC title

• A61L31/10

  Macromolecular materials · CPC title