Functionalized poly (propylene fumarate) polymers made by ring opening polymerization using magnesium catalysts

US11499008B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11499008-B2
Application numberUS-201816483122-A
CountryUS
Kind codeB2
Filing dateFeb 2, 2018
Priority dateFeb 2, 2017
Publication dateNov 15, 2022
Grant dateNov 15, 2022

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  2. Abstract

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  5. First independent claim

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Abstract

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An end and monomer functionalized poly(propylene fumarate) polymer and methods for preparing this polymer, comprising isomerized residue of a maleic anhydride monomer and a functionalized propylene oxide monomer according to the formula:where n is an integer from more than 1 to 100; R is the residue of an initiating alcohol having a propargyl, norbornene, ketone or benzyl functional group; and R′ is a second functional group selected from the group consisting of propargyl groups, 2-nitrophenyl groups, and combinations thereof are disclosed. The end and monomer functional groups allow for post-polymerization modification with bioactive materials using “click” chemistries and use of the polymer for a variety of applications in medical fields, including, for example, 3-D printed polymer scaffold.

First claim

Opening claim text (preview).

What is claimed is: 1. An end and monomer functionalized poly(propylene fumarate) polymer comprising an isomerized residue of a maleic anhydride monomer and a functionalized propylene oxide monomer having the formula: where n is an integer from more than 1 to 100; R is the residue of an initiating alcohol having a propargyl, norbornene, ketone or benzyl functional group; and R′ is a second functional group selected from the group consisting of propargyl groups, 2-nitrophenyl groups, and combinations thereof. 2. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 3. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 4. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 5. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 6. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 7. The end and monomer functionalized polypropylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100. 8. The end and monomer functionalized poly(propylene fumarate) polymer of claim 1 having the formula: where n is an integer from about more than 1 to about 100.

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Classifications

  • Alkali metals, alkaline earth metals, beryllium, magnesium, copper, silver, gold, zinc, cadmium, mercury, manganese, or compounds thereof {(C08G63/823 takes precedence)} · CPC title

  • C08G63/52Primary

    Polycarboxylic acids or polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation · CPC title

  • Lactones or lactides · CPC title

  • Polymers modified by chemical after-treatment · CPC title

  • acyclic · CPC title

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What does patent US11499008B2 cover?
An end and monomer functionalized poly(propylene fumarate) polymer and methods for preparing this polymer, comprising isomerized residue of a maleic anhydride monomer and a functionalized propylene oxide monomer according to the formula:where n is an integer from more than 1 to 100; R is the residue of an initiating alcohol having a propargyl, norbornene, ketone or benzyl functional group; and …
Who is the assignee on this patent?
Becker Matthew, Wilson James A, Chen Yusheng, and 1 more
What technology area does this patent fall under?
Primary CPC classification C08G63/52. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).