Fluid injector system volume compensation system and method

Patent metadata

Field	Value
Publication number	US-11478581-B2
Application number	US-201816621164-A
Country	US
Kind code	B2
Filing date	Aug 28, 2018
Priority date	Aug 31, 2017
Publication date	Oct 25, 2022
Grant date	Oct 25, 2022

Abstract

A system and method for correcting a volume of fluid delivered by a fluid injector during an injection procedure is described. The method included determining and compensating for a volume factor associated with compliance of the fluid injector system and correcting for the volume by one of over-driving the distance that the drive member travels in a fluid reservoir, under-driving the distance that the drive member travels in the fluid reservoir, or lengthening or shortening a fluid delivery time.

First claim

The invention claimed is:

1. A method for correcting a volume of fluid delivered by a fluid injector system during an injection procedure using one or more fluid reservoirs, the method comprising:
determining a fluid volume of a first fluid in at least one of the fluid reservoirs of the fluid injector system;
determining a pressure at which a first programmed volume of the first fluid is to be injected;
determining a system volume compliance according to Equation (1) for the at least one fluid reservoir, one or more fluid injector mechanical components associated with the at least one fluid reservoir, and one or more tubing system components:
C 1 =A 1 ·V 1 +B 1 ·P 1 +O 1   (1)

where C 1 is the system volume compliance of the at least one fluid reservoir, A 1 is a position scalar of the at least one fluid reservoir, V 1 is available volume of the at least one fluid reservoir, B 1 is a pressure constant of the at least one fluid reservoir, P 1 is a pressure of fluid within the at least one fluid reservoir, and O 1 is a compensation factor of the at least one fluid reservoir;
predicting a volume compliance factor of fluid in the at least one fluid reservoir according to Equation (2):
VC 1 =PV 1 +C 1   (2)

where VC 1 is the volume compliance factor of the fluid in the at least one fluid reservoir, PV 1 is a programmed volume of the first fluid, and C 1 is the system volume compliance of the at least one fluid reservoir; and
compensating for the volume compliance factor to deliver a programmed fluid volume by one of over-driving a distance that a drive member travels in the at least one fluid reservoir, under-driving the distance that the drive member travels in the at least one fluid reservoir, increasing a delivery time of the fluid in the at least one fluid reservoir, and decreasing the delivery time of the fluid in the at least one fluid reservoir.

2. The method of claim 1 , wherein the at least one fluid reservoir comprises at least one first fluid reservoir containing the first fluid and at least one second fluid reservoir containing a second fluid, wherein the method further comprises:
determining a fluid volume of the second fluid in the at least one second fluid reservoir of the fluid injector system;
determining a second pressure at which a programmed volume of the second fluid is to be injected;
determining a system volume compliance according to Equation (1) for the at least one second fluid reservoir, one or more fluid injector mechanical components associated with the second reservoir, and one or more tubing system components:
C 2 =A 2 ·V 2 +B 2 ·P 2 +O 2   (1)

where C 2 is the system volume compliance for the at least one second fluid reservoir, A 2 is a position scalar for the at least one second fluid reservoir, V 2 is available volume for the at least one second fluid reservoir, B 2 is a pressure constant for the at least one second fluid reservoir, P 2 is a pressure of fluid within the at least one second fluid reservoir, and O 2 is a compensation factor for the at least one second fluid reservoir;
predicting a volume compliance factor of the fluid in the at least one second reservoir according to Equation (2):
VC 2 =PV 2 +C 2   (2)

where VC 2 is the volume compliance factor of the at least one second fluid reservoir, PV 2 is a programmed volume of the at least one second fluid reservoir, and C 2 is a system volume compliance of the at least one second fluid reservoir; and
compensating for the volume compliance factor of the at least one second fluid reservoir to deliver the programmed fluid volume of the second fluid by one of over-driving a distance that a drive member travels in the at least one second fluid reservoir, under-driving a distance that the drive member travels in the at least one second fluid reservoir, increasing a delivery time of the second fluid in the at least one second fluid reservoir, and decreasing the delivery time of the second fluid in the at least one second fluid reservoir.

3. The method of claim 1 , wherein the at least one fluid reservoir comprises at least one first fluid reservoir containing the first fluid, at least one second fluid reservoir containing a second fluid, and at least one third fluid reservoir containing a third fluid.

4. The method of claim 1 , further comprising determining whether the at least one fluid reservoir contains at least a volume of fluid corresponding to the programmed volume plus an amount of fluid equal to the system volume compliance according to Equation (1).

5. The method of claim 3 , wherein the at least one first fluid reservoir, the at least one second fluid reservoir, and the at least one third fluid reservoir are independently selected from a group consisting of a syringe, a rolling diaphragm syringe, a peristaltic pump, and a compressible bag.

6. The method of claim 3 , wherein at least one of the at least one first fluid reservoir, the at least one second fluid reservoir, and the at least one third fluid reservoir is a syringe.

7. The method of claim 6 , wherein the syringe comprises a plunger operatively connected to the drive member, wherein the drive member is selected from a linear actuated piston and a motor driven piston.

8. The method of claim 3 , wherein at least one of the at least one first fluid reservoir, the at least one second fluid reservoir, and the at least one third fluid reservoir is a rolling diaphragm syringe.

9. The method of claim 6 , wherein the system volume compliance of Equation (1) is determined according to Equation (3):
z −1 =c·y 0.5 +b/x 0.5 +a   (3)

where z is the system volume compliance (C), c is the position scalar (A), y is the available volume in the at least one fluid reservoir (V 1 ), b is the pressure constant (B), x is the pressure of the fluid with the at least one fluid reservoir (P 1 ), and a is the compensation factor (O).

10. The method of claim 9 , wherein a has a value ranging from 0.112 to 0.115, b has a value ranging from 10.35 to 10.45, and c has a value ranging from −0.01465 to −0.01495.

11. The method of claim 1 , wherein compensating for the volume compliance factor of the at least one fluid reservoir comprises:
over-driving the distance that the drive member travels in the at least one fluid reservoir; and
injecting an additional volume of the first fluid equal to the volume compliance factor.

12. The method of claim 11 , further comprising closing a valve to fluidly isolate the at least one fluid reservoir from a patient after injecting the additional volume of the first fluid.

13. The method of claim 1 , wherein compensating for the volume compliance factor of the at least one fluid reservoir comprises increasing a delivery time of the first fluid in the at least one fluid reservoir.

14. The method of claim 13 , wherein increasing the delivery time of the first fluid comprises increasing the delivery time by an amount sufficient to deliver an additional volume of the first fluid equal to the volume compliance factor.

15. The method of claim 1 , further comprising reporting to a user a value corresponding to a corrected volume of a fluid being delivered to a patient from the at least one fluid reservoir, wherein the corrected volume accounts for the programmed volume and the system volume compliance.

16. A fluid delivery system comprising:
a fluid injector;
at least one first fluid reservoir configured to contain a first fluid;
at least one first drive member configured to drive

Assignees

• Bayer Healthcare Llc

Inventors

• Mcdermott Michael
• Spohn Michael
• Barone William
• Marsh Chelsea

Classifications

• A61M5/16881

  Regulating valves (on-off valves, e.g. clamps A61M39/28) · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M5/1408

  in parallel, e.g. manifolds, sequencing valves (access sites A61M39/02; tube connectors A61M39/10) · CPC title

• A61M2205/3362

  with minimised length of fluid lines; Taking into account the elastic expansion of fluid lines to increase accuracy · CPC title