Two-paste type dental resin-reinforced glass ionomer cement composition

Patent metadata

Field	Value
Publication number	US-11478408-B2
Application number	US-202016829226-A
Country	US
Kind code	B2
Filing date	Mar 25, 2020
Priority date	Mar 26, 2019
Publication date	Oct 25, 2022
Grant date	Oct 25, 2022

Abstract

An object of the present invention is to provide a two-paste type dental resin-reinforced glass ionomer cement composition which exhibit high surface curability even under wet conditions, which makes difficult for the surface to become cloudy even if moisture comes in contact with at the initial stage of curing, exhibits high mechanical properties, low water absorption expansion and excellent coloring resistance in the set product and is also excellent in storage stability. The two-paste type dental resin-reinforced glass ionomer cement composition of the present invention consists of two pastes, wherein at least one of the two pastes contains (a) acid-reactive glass powder, (b) polymer of acidic group-containing polymerizable monomer, (c) water, (d) hydroxyl group-containing (meth)acrylate-based polymerizable monomer, (e) tri or more functional (meth)acrylamide-based polymerizable monomer, and (f) polymerization initiator, wherein the paste containing the (c) water does not contain at least one of the (a) acid-reactive glass powder and the (b) polymer of acidic group-containing polymerizable monomer.

First claim

What is claimed is:

1. A two-paste type dental resin-reinforced glass ionomer cement composition comprising two pastes, wherein
at least one of the two pastes contains (a) acid-reactive glass powder, (b) polymer of acidic group-containing polymerizable monomer, (c) water, (d) hydroxyl group-containing (meth)acrylate-based polymerizable monomer, (e) tri or more functional (meth)acrylamide-based polymerizable monomer, and (f) polymerization initiator,
the paste containing the (c) water does not contain at least one of the (a) acid-reactive glass powder and the (b) polymer of acidic group-containing polymerizable monomer, and
the (d) hydroxyl group-containing (meth)acrylate-based polymerizable monomer contains both a mono functional (meth)acrylate-based polymerization monomer that has a hydroxyl group and a bi to tetra functional (meth)acrylate-based polymerizable monomer that has hydroxyl group, and a compounding ratio of the mono functional (meth)acrylate-based polymerization monomer that has a hydroxyl group and the bi to tetra functional (meth)acrylate-based polymerizable monomer that has hydroxyl group is 1:2 to 4:1 by weight.

2. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 1 , wherein
at least one of the two pastes further contains (g) acidic group-containing polymerizable monomer, wherein
the paste containing the (c) water does not contain at least one of the (a) acid-reactive glass powder and the (g) acidic group-containing polymerizable monomer.

3. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 1 , wherein
the (b) polymer of acidic group-containing polymerizable monomer is a polymer of an α,β-unsaturated carboxylic acid.

4. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 1 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a tetra or more functional (meth)acrylamide-based polymerizable monomer.

5. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 1 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a compound represented by formula (1):

wherein R 1 represents a hydrogen atom or a methyl group and R 1 s may be the same or different from each other, and R 2 represents a linear or branched alkylene group having 2 to 6 carbon atoms which may have a substituent and R 2 s may be the same or different from each other.

6. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 5 , wherein
all R 1 s in the formula (1) are hydrogen atom.

7. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 1 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a compound represented by formula (2):

wherein R 1 represents a hydrogen atom or a methyl group and R 1 s may be the same or different from each other.

8. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 7 , wherein
all R 1 s in the formula (2) are hydrogen atom.

9. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 2 , wherein
the (b) polymer of acidic group-containing polymerizable monomer is a polymer of an α,β-unsaturated carboxylic acid.

10. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 9 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a tetra or more functional (meth)acrylamide-based polymerizable monomer.

11. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 10 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a compound represented by formula (1):

wherein R 1 represents a hydrogen atom or a methyl group and R 1 s may be the same or different from each other, and R 2 represents a linear or branched alkylene group having 2 to 6 carbon atoms which may have a substituent and R 2 s may be the same or different from each other.

12. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 11 , wherein
all R 1 s in the formula (1) are hydrogen atom.

13. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 10 , wherein
the (e) tri or more functional (meth)acrylamide-based polymerizable monomer is a compound represented by formula (2):

wherein R 1 represents a hydrogen atom or a methyl group and R 1 s may be the same or different from each other.

14. The two-paste type dental resin-reinforced glass ionomer cement composition of claim 13 , wherein
all R 1 s in the formula (2) are hydrogen atom.

Assignees

• Shofu Inc

Inventors

• Uchida Jun
• Kumagai Tomohiro
• Hiratsuka Ken

Classifications

• A61K6/30

  Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives · CPC title

• A61K6/62

  Photochemical radical initiators · CPC title

• A61K6/887

  Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• A61K6/889 Primary

  Polycarboxylate cements; Glass ionomer cements · CPC title

• A61K6/40

  Primers (for dental adhesives A61K6/30) · CPC title