Cohesive thin liquids to promote safe swallowing in dysphagic patients
US-10582722-B2 · Mar 10, 2020 · US
US11478010B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11478010-B2 |
| Application number | US-201515327745-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 20, 2015 |
| Priority date | Jul 21, 2014 |
| Publication date | Oct 25, 2022 |
| Grant date | Oct 25, 2022 |
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Nutritional products, uses thereof, methods for the manufacture and methods for improving the cohesiveness of the nutritional products are disclosed. The nutritional products have improved cohesiveness for promoting safer swallowing of food boluses for individuals having swallowing difficulties such as dysphagia.
Opening claim text (preview).
The invention claimed is: 1. A method for treating a swallowing disorder in a patient in need thereof, the method comprising administering to the patient a nutritional product comprising an aqueous solution consisting essentially of a beta-glucan in a concentration of from 0.01 wt % to 10 wt % of the aqueous solution, the beta-glucan being homopolysaccharides of D-glucopyranose monomers linked by (1→3), (1→4)-β-glycosidic bonds, and the nutritional product comprises an amount of the beta-glucan effective for providing to the nutritional product (i) a shear viscosity of less than 200 mPas when measured at a shear rate of 50s −1 ; and (ii) a relaxation time, determined by a Capillary Breakup Extensional Rheometry (CaBER) experiment, of more than 10 ms (milliseconds) at a temperature of 20° C. 2. The method according to claim 1 for promoting safe swallowing of nutritional products in a patient in need of safe swallowing of the nutritional products. 3. The method according to claim 1 for mitigating the risks of aspiration during swallowing of nutritional products in a patient in need of mitigating the risks of aspiration during swallowing of the nutritional products. 4. The method according to claim 1 , wherein the aqueous solution consists of the beta-glucan and at least one additional ingredient selected from the group consisting of an acidulant, a thickener, a buffer or an agent for pH adjustment, a chelating agent, a colorant, an emulsifier, an excipient, a flavor agent, a mineral, an osmotic agent, a pharmaceutically acceptable carrier, a preservative, a stabilizer, a sugar, a sweetener, a texturizer, and a vitamin.
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