Novel anthranilic amides and the use thereof
US-2016221975-A1 · Aug 4, 2016 · US
Anthranilic amides and the use thereof
US11465978B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11465978-B2 |
| Application number | US-201415021592-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 11, 2014 |
| Priority date | Sep 11, 2013 |
| Publication date | Oct 11, 2022 |
| Grant date | Oct 11, 2022 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.
First claim
Opening claim text (preview).
We claim: 1. A compound of formula: or a pharmaceutically acceptable salt thereof. 2. A composition, comprising the compound of claim 1 , and a pharmaceutically acceptable carrier. 3. The composition of claim 2 , wherein the composition is formulated for oral, intravenous, intradermal, intramuscular, and subcutaneous administration. 4. The composition of claim 3 , wherein the composition comprises a product for oral delivery comprising a concentrate, a dried powder, a liquid, a capsule, a pellet, and a pill. 5. A method of inhibiting MEK5 enzymatic activity in a subject comprising: administering to the subject an effective amount of the compound of claim 1 , thereby inhibiting MEK5 enzymatic activity.
Assignees
Inventors
Classifications
having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms · CPC title
having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups · CPC title
having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups · CPC title
- C07D295/16Primary
acylated on ring nitrogen atoms · CPC title
Antineoplastic agents · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US11465978B2 cover?
- Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK…
- Who is the assignee on this patent?
- The Administrators Of The Tulane Educational Fund, Duquesne Univ Of The Holy Ghost
- What technology area does this patent fall under?
- Primary CPC classification C07D295/16. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 11 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).