Catalysts and use thereof in the production of polyurethanes
US-9416215-B2 · Aug 16, 2016 · US
Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same
US11465135B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11465135-B2 |
| Application number | US-201916976151-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 24, 2019 |
| Priority date | Feb 28, 2018 |
| Publication date | Oct 11, 2022 |
| Grant date | Oct 11, 2022 |
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Abstract
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The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using the chiral organocatalytic compound. According to the present invention, the bifunctional chiral organocatalytic compound having excellent enantioselectivity can be easily synthesized, gamma-amino acids with high optical selectivity can be obtained at a high yield by an economical and convenient method using the chiral organocatalytic compound, and various (R)-configuration gamma-amino acids, which are not present in nature, can be produced with high optical purity in large quantities by using a small amount of a catalyst, and therefore, the present invention can be widely utilized in various industrial fields including the pharmaceutical industry.
First claim
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The invention claimed is: 1. A chiral organocatalyst selected from the group consisting of the following compounds:
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Classifications
having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring · CPC title
2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles · CPC title
Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom · CPC title
1,4-additions, e.g. conjugate additions · CPC title
containing six-membered aromatic rings · CPC title
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- What does patent US11465135B2 cover?
- The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using the chiral organocatalytic compound. According to the present invention, the bifunctional chiral organocatalytic compound having excellent enantioselectivity ca…
- Who is the assignee on this patent?
- Univ Korea Res & Bus Found
- What technology area does this patent fall under?
- Primary CPC classification B01J31/0237. Mapped technology areas include Operations & Transport.
- When was this patent published?
- Publication date Tue Oct 11 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).