Biomarker of the colour perception of a mammal subject based on pupil frequency tagging
US-11229356-B2 · Jan 25, 2022 · US
US11464407B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11464407-B2 |
| Application number | US-201816499782-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 29, 2018 |
| Priority date | Mar 31, 2017 |
| Publication date | Oct 11, 2022 |
| Grant date | Oct 11, 2022 |
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A method for generating an indicator or biomarker of colour perception in a mammalian subject, where the method may include submitting the mammalian subject to a multicoloured dynamic stimulus comprising displaying, on a display device. The method may include controlling a change over time of at least one of the two colours of the multicolour pattern when displaying the dynamic multicolour stimulus, to vary the displayed luminance of this colour (usually several times). The method may include acquiring, by using an image acquisition device, an oscillatory response of a pupil of the mammalian subject. The method may include generating, from the acquired response, a signal representative of the power of the pupil's oscillatory response as a function of the change over time of at least one of the two colours when displaying the dynamic multicoloured stimulus.
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The invention claimed is: 1. A method for controlling a computer process in a personalised manner in a computer system, comprising the following steps: determining at least one chromatic iso-luminance information for an individual, wherein determining the at least one chromatic iso-luminance information comprises: submitting the individual to a dynamic multicolour stimulus comprising displaying, on a display device of the computer system, a multicolour pattern, at least two colours of which are periodically inverted at a so-called marking frequency, controlling a change over time of at least one of the at least two colours of the multicolour pattern when displaying the dynamic multicolour stimulus, to vary a displayed luminance of that colour and to vary a luminance difference between the at least two colours, acquiring, by an image acquisition device, an oscillatory response of at least one pupil of the individual, when displaying the dynamic multicolour stimulus, generating, from the acquired oscillatory response, a signal representative of a power of the oscillatory response of the at least one pupil as a function of the change over time of at least one of the at least two colours and a difference in luminance between the at least two colours when displaying the dynamic multicolour stimulus, and wherein the at least one chromatic iso-luminance information comprises a bicolour iso-luminance configuration of the at least two colours in the dynamic multicolour stimulus corresponding to a minimum of the signal representative of the power, and using the at least one chromatic iso-luminance information to determine input data of the computer process in the computer system. 2. The method according to claim 1 , wherein the computer process is a process for a calibration of a display screen of the computer system, in which a display of a pixel is corrected as a function of said at least one chromatic iso-luminance information. 3. The method according to claim 2 , wherein the at least one chromatic iso-luminance information comprises, for at least one colour pair among a red-green pair, a red-blue pair, and a green-blue pair of a red-green-blue colour space, a value determined for a first colour when a second colour takes a reference value. 4. The method according to claim 3 , in which a default chromatic iso-luminance value of the first colour is obtained for an initial calibration of the display screen when the second colour takes a reference value, and the correcting the pixel comprises adjusting a first colour or a second colour of the pixel according to a value differential between the default chromatic iso-luminance value and the determined value of the chromatic iso-luminance. 5. The method according to claim 4 , wherein the correction of the pixel comprises modifying the first colour or the second colour of the pixel by a value equal to said value differential. 6. The method according to claim 4 , wherein the correction of the pixel comprises modifying the first colour of the pixel by a value that is a function of both the value differential and a distance of the second colour of the pixel from the reference value. 7. The method according to claim 6 , wherein this function is linear with respect to said distance between the second colour of the pixel and the reference value. 8. The method according to claim 3 , comprising determining two chromatic iso-luminance information for two different colour pairs among the red-green pair, the red-blue pair and the green-blue pair of the red-green-blue colour space, each chromatic iso-luminance information comprising a determined value for a first colour when the second colour takes a reference value. 9. The method according to claim 2 , comprising determining two chromatic iso-luminance information for two different colour pairs among a red-green pair, a red-blue pair, and a green-blue pair of the red-green-blue colour space, each chromatic iso-luminance information comprising a determined value for a first colour when a second colour takes a reference value. 10. The method according to claim 9 , wherein the correction of a pixel on the display screen comprises adjusting a colour triplet defining the pixel according to an initial calibration of the display screen, based on two value differentials obtained for the two colour pairs, each value differential representing the difference between a default value of chromatic iso- luminance for the first colour of the colour pair when the second colour takes the reference value and the determined value of chromatic iso-luminance. 11. The method according to claim 10 , wherein the colour triplet is adjusted at constant pixel luminance. 12. The method according to claim 10 , wherein the adjustment of the colour triplet is performed at constant value of one of its colour components. 13. The method according to claim 1 , wherein the computer process using the at least one chromatic iso-luminance information is a procedure for identifying or authenticating the individual. 14. The method according to claim 13 , further comprising comparing the at least one determined chromatic iso-luminance information with at least one reference chromatic iso-luminance information stored in a memory of the computer system in association with an identifier of individual, and validating an identification or authentication of the individual only if the chromatic iso-luminance information matches. 15. The method according to claim 14 , comprising determining two pieces of chromatic iso-luminance information for two different colour pairs among a red-green pair, a red-blue pair and a green-blue pair of the red-green-blue colour space, each chromatic iso-luminance information comprising a determined value for a first colour when the second colour takes a reference value. 16. The method according to claim 15 , further comprising a preliminary step of identifying individual to retrieve the at least one reference chromatic iso-luminance information associated with said individual, prior to said comparison. 17. The method according to claim 14 , further comprising a preliminary step of identifying individual to retrieve the at least one reference chromatic iso-luminance information associated with said individual, prior to said comparison. 18. The method according to claim 14 , further comprising determining, based on the identification of the individual, at least a limited range of change values for changing over time the colour to be changed of the multicolour pattern when determining chromatic iso-luminance information. 19. The method according to claim 13 , further comprising determining, based on an identification of the individual, at least a limited range of change values for changing over time the colour to be changed of the multicolour pattern when determining chromatic iso-luminance information. 20. A system for controlling a computer process in a personalised manner in a computer system, comprising: a subsystem for determining at least one chromatic iso-luminance information for an individual, and a process control module configured to use the at least one chromatic iso-luminance information to determine input data of the computer process in the computer system, the subsystem for determining iso-luminance information comprising: a display device, a computer module for stimulating the individual by means of a dynamic multicolour stimulus, the computer module controlling a display, on the display device, of a multicolour pattern, at least two colours of which
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