Applicator for applying a microneedle array to skin

Patent metadata

Field	Value
Publication number	US-11458289-B2
Application number	US-201816754881-A
Country	US
Kind code	B2
Filing date	Oct 17, 2018
Priority date	Oct 17, 2017
Publication date	Oct 4, 2022
Grant date	Oct 4, 2022

Abstract

An applicator and method for applying a microneedle array to skin. The applicator can include a body having a first portion and a second portion defining a cavity, the second portion having a slot presented on an outside surface for insertion of the microneedle array into the cavity. The first portion and the second portion are slidable relative to one other along an axis enabling the body to be in an unprimed configuration and a primed configuration. The applicator further includes a door operable with the second portion, the door being movable from a first door position to a second door position, wherein when the device is in the unprimed configuration, the door at least partially obstructs the slot and access into the cavity. When the device is in the primed configuration, the door does not obstruct the slots and enables access into the cavity.

First claim

What is claimed is:

1. A device for applying a microneedle array to a surface, said device comprising:
a body comprising a first portion and a second portion defining a cavity, said second portion comprising a slot presented on an outside surface of said second portion for insertion of the microneedle array into said cavity, said first portion and said second portion slidable relative to one other along an axis thus enabling said device to be in an unprimed configuration and a primed configuration; and
a plunger disposed in said cavity, said plunger comprising a first plunger end and a second plunger end, said plunger movable from a first position when said device is in said unprimed configuration to a second position when said device is in said primed configuration, and
a microneedle array;
wherein when said device is in said primed configuration, the microneedle array is adapted to be inserted into said cavity through said slot and positioned proximate said second plunger end, and further wherein the plunger is adapted to contact the microneedle array when the device is in the primed configuration and the first portion and the second portion of the body are axially compressed but before the plunger is released.

2. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are in contact with one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

3. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 2 mm from one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

4. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 1 mm from one when the plunger is in the second position but before the first and second portions of the body are axially compressed.

5. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 0.5 mm from one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

6. The device of claim 1 , wherein said second portion comprises an inner surface comprising a low surface energy material, wherein when said plunger moves from said first position to said second position, any friction between the microneedle array and said inner surface, should they be in slidable engagement with one another, is minimized.

7. The device of claim 1 , further comprising a biasing member for biasing said plunger to said first position when said device is in said unprimed configuration.

8. The device of claim 7 , wherein said biasing member comprises a compression spring and wherein said compression spring is compressed and energized when said plunger is in said second position when said device is in said primed configuration.

9. The device of claim 1 , further comprising visual indicia proximate the slot identifying a location of the slot to a user.

Assignees

• Kindeva Drug Delivery Lp

Inventors

• Moeckly Craig S
• Frits Michael J
• Gowers Steven P
• Ley Gregory R
• Mathias Richard R
• Selby Robert G M
• Simmers Ryan Patrick
• Sivigny Michael B
• Strange Daniel G T

Classifications

• A61M2037/0023

  Drug applicators using microneedles · CPC title

• A61M35/003

  Portable hand-held applicators having means for dispensing or spreading integral media (hand-held massage devices with liquid delivery A61H7/003) · CPC title

• A61M37/0015 Primary

  by using microneedles · CPC title

• A61M37/00

  Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title

• A61M2037/0061

  Methods for using microneedles · CPC title