Compositions and methods for viral sensitization
US-2024360115-A1 · Oct 31, 2024 · US
US11458177B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11458177-B2 |
| Application number | US-201816487506-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 11, 2018 |
| Priority date | Feb 22, 2017 |
| Publication date | Oct 4, 2022 |
| Grant date | Oct 4, 2022 |
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The present invention relates to Siphoviridae bacteriophage Ent-FAP-4 (accession number KCTC 12854BP), separated from nature, which is capable of specifically killing Enterococcus faecium and has a genome expressed by sequence number 1, a pharmaceutical composition, which comprises same as an active ingredient, and a method for preventing or treating diseases, induced by Enterococcus faecium, by administering the pharmaceutical composition.
Opening claim text (preview).
The invention claimed is: 1. A method of suppressing diseases caused by a bacterial strain of Enterococcus faecium and alleviating pathological condition of the diseases caused by the bacterial strain of Enterococcus faecium, comprising: administering to an animal other than a human a composition comprising Siphoviridae bacteriophage Ent-FAP-4 which has an ability to specifically kill the bacterial strain of Enterococcus faecium and has the genome represented by the nucleic acid sequence of SEQ ID NO: 1, and is deposited as the accession number of KCTC 12854BP, wherein the diseases are urinary tract infections, wound infections, bacteremia or endocarditis.
Viruses as such, e.g. new isolates, mutants or their genomic sequences · CPC title
Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof (preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K39/00) · CPC title
Viruses; Subviral particles; Bacteriophages · CPC title
Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent · CPC title
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