Use of agarobiose or agarooligosaccharide having anticariogenic activity

US11458152B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11458152-B2
Application numberUS-202016985850-A
CountryUS
Kind codeB2
Filing dateAug 5, 2020
Priority dateNov 15, 2016
Publication dateOct 4, 2022
Grant dateOct 4, 2022

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a use of an agarobiose or agarooligosaccharides having anticariogenic activity. More specifically, a lower concentration of agarobiose or agarooligosaccharides than the concentration of xylitol suppresses the growth of Streptococcus mutans and suppresses acid production, and thus can be used for anti-cariogenic purposes.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for treating or alleviating an oral disease of a subject, comprising administering a therapeutically effective amount of agarobiose, agarooligosaccharides, or combination thereof to the subject, wherein the oral disease is any one selected from the group consisting of dental caries, gingivitis, periodontitis, oral mucous ulcers, halitosis, and xerostomia, and wherein the agarooligosaccharides are a mixture of agarobiose, agarotetraose, agarohexaose, and agarooctaose. 2. The method of claim 1 , wherein the agarooligosaccharides are obtained from an acid hydrolysate of agarose. 3. The method of claim 1 , wherein the agarobiose is obtained by separating and purifying an acid hydrolysate of agarose through gel permeation chromatography. 4. The method of claim 1 , wherein the oral disease is caused by one or more oral microorganisms selected from the group consisting of Streptococcus mutans, Porphyromonas gingivalis, Prevotella intermedia, Actinobacillus actinomycetemcomitans , and Candida albicans.

Assignees

Inventors

Classifications

  • A61K31/702Primary

    Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages · CPC title

  • A61K8/73Primary

    Polysaccharides · CPC title

  • Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

  • using additives (addition of substantially indigestible substances A23L33/21) · CPC title

  • Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

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Frequently asked questions

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What does patent US11458152B2 cover?
The present invention relates to a use of an agarobiose or agarooligosaccharides having anticariogenic activity. More specifically, a lower concentration of agarobiose or agarooligosaccharides than the concentration of xylitol suppresses the growth of Streptococcus mutans and suppresses acid production, and thus can be used for anti-cariogenic purposes.
Who is the assignee on this patent?
Univ Korea Res & Bus Found
What technology area does this patent fall under?
Primary CPC classification A61K31/702. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Oct 04 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).