Optimizing energy transmission in a leadless tissue stimulation system

Patent metadata

Field	Value
Publication number	US-11452879-B2
Application number	US-201916601854-A
Country	US
Kind code	B2
Filing date	Oct 15, 2019
Priority date	May 23, 2007
Publication date	Sep 27, 2022
Grant date	Sep 27, 2022

Abstract

Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.

First claim

What is claimed is:

1. A method of locating an acoustic receiver-stimulator, the method comprising:
transmitting, via a controller-transmitter, focused acoustic energy to a tissue location;
receiving, at the receiver-stimulator, the focused acoustic energy;
converting, via the receiver-stimulator, the focused acoustic energy into electrical energy;
delivering, via the receiver-stimulator, the electrical energy to tissue; and
detecting, via one or more electrodes of the controller-transmitter that are electrically connected to the tissue, the delivered electrical energy to determine whether the receiver-stimulator is present at the tissue location.

2. The method of claim 1 wherein the method further comprises, after determining that the receiver-stimulator is present at the tissue location, adjusting the controller-transmitter to transmit additional focused acoustic energy to the tissue location.

3. The method of claim 2 wherein adjusting the controller-transmitter includes adjusting an array of acoustic transducers to transmit the additional focused acoustic energy to the tissue location.

4. The method of claim 1 wherein the method further comprises, after determining that the receiver-stimulator is present at the tissue location, transmitting additional acoustic energy to the tissue location, via the controller-transmitter, to stimulate the tissue.

5. The method of claim 1 wherein the tissue location is one of a plurality of tissue locations, and wherein transmitting the focused acoustic energy includes sequentially steering the focused acoustic energy to individual ones of the tissue locations until the delivered electrical energy is detected.

6. A method of locating an acoustic receiver-stimulator, the method comprising:
transmitting, via a controller-transmitter, focused acoustic energy to a tissue location;
receiving, at the receiver-stimulator, the focused acoustic energy;
converting, via the receiver-stimulator, the focused acoustic energy into electrical energy;
delivering, via the receiver-stimulator, the electrical energy to tissue; and
detecting, via a spike detector of the controller-transmitter, an electrical spike indicative of the delivered electrical energy to determine whether the receiver-stimulator is present at the tissue location.

7. A method for transmitting acoustic energy into a body, the method comprising:
transmitting acoustic energy into a region of the body;
receiving the acoustic energy at an acoustic receiver located in the region of the body;
converting the acoustic energy into electrical energy;
delivering the electrical energy into the region of the body; and
detecting the delivered electrical energy via one or more electrodes of an acoustic transmitter that are in contact with the body to determine whether the transmitted acoustic energy is focused on the acoustic receiver.

8. The method of claim 7 wherein transmitting the acoustic energy includes transmitting the acoustic energy via the acoustic transmitter;
converting the acoustic energy into electrical energy includes converting the acoustic energy into electrical energy via circuitry of the acoustic receiver; and
delivering the electrical energy into the region of the body includes delivering the electrical energy via at least one electrode of the acoustic receiver that is electrically connected to the region of the body.

9. The method of claim 7 wherein the method further comprises, after determining that the acoustic energy is focused on the acoustic receiver, transmitting additional acoustic energy to the acoustic receiver.

10. The method of claim 9 wherein the method further comprises:
converting the additional acoustic energy into additional electrical energy; and
delivering the additional electrical energy into the region of the body to stimulate tissue at the region in the body.

11. The method of claim 10 wherein the tissue is cardiac tissue.

12. The method of claim 7 wherein the method further comprises implanting the acoustic receiver in the region of the body.

13. The method of claim 7 wherein detecting the delivered electrical energy via the one or more electrodes further includes detecting an electrical spike via a spike detector of the controller-transmitter electrically coupled to the one or more electrodes.

14. A method for transmitting acoustic energy into tissue, the method comprising:
transmitting an acoustic locator signal into the tissue;
receiving the acoustic locator signal at an acoustic receiver implanted in the tissue;
generating an electrical location signal;
transmitting the electrical location signal into the tissue;
detecting the electrical location signal via one or more electrodes of an acoustic transmitter that are electrically connected to the tissue; and
transmitting focused acoustic energy toward a region of the tissue associated with the detected electrical location signal.

15. The method of claim 14 wherein transmitting the focused acoustic energy toward the region of the tissue includes adjusting a transducer array to transmit the focused acoustic energy based on a characteristic of the electrical location signal.

16. The method of claim 14 wherein transmitting the acoustic locator signal includes transmitting a wide beam acoustic burst.

17. The method of claim 14 wherein the tissue is cardiac tissue.

18. The method of claim 17 wherein the method further comprises:
converting the focused acoustic energy into electrical energy; and
delivering the electrical energy into the region of cardiac tissue to stimulate the cardiac tissue.

19. A method for transmitting acoustic energy into tissue, the method comprising:
transmitting an acoustic locator signal into the tissue;
receiving the acoustic locator signal at an acoustic receiver implanted in the tissue;
generating an electrical location signal;
transmitting the electrical location signal into the tissue;
detecting the electrical location signal; and
transmitting focused acoustic energy toward a region of the tissue associated with the detected electrical location signal, wherein transmitting the focused acoustic energy toward the region of the tissue includes adjusting a transducer array to transmit the focused acoustic energy based on a characteristic of the electrical location signal, and wherein the characteristic is at least one of a frequency, duration, amplitude, phase, and time of flight of the electrical location signal.

20. A method for transmitting acoustic energy into tissue, the method comprising:
transmitting an acoustic locator signal into the tissue;
receiving the acoustic locator signal at an acoustic receiver implanted in the tissue;
generating an electrical location signal;
transmitting the electrical location signal into the tissue;
detecting the electrical location signal by detecting an electrical spike at one or more electrodes electrically connected to the tissue; and
transmitting focused acoustic energy toward a region of the tissue associated with the detected electrical location signal.

Assignees

• Ebr Systems Inc

Inventors

• Willis N Parker
• Brisken Axel F
• Cowan Mark W
• Pare Michael
• Fowler Robert
• Brennan James

Classifications

• A61N1/3787 Primary

  from an external energy source · CPC title

• A61N1/3756

  Casings with electrodes thereon, e.g. leadless stimulators · CPC title

• A61B5/0093

  Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy · CPC title

• A61N1/37252

  Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data · CPC title

• A61N1/37217

  characterised by the communication link, e.g. acoustic or tactile · CPC title