Finding the origin of an arrythmia

Patent metadata

Field	Value
Publication number	US-11445935-B2
Application number	US-201916663945-A
Country	US
Kind code	B2
Filing date	Oct 25, 2019
Priority date	Nov 26, 2018
Publication date	Sep 20, 2022
Grant date	Sep 20, 2022

Abstract

A probe generates location signals, and has an electrode at a distal end which acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.

First claim

We claim:

1. A medical apparatus, comprising:
a probe, configured to be inserted into a chamber of a heart of a human subject, and to generate location signals indicative of location coordinates of a distal end of the probe, and comprising at least two pairs of electrodes at the distal end, which are configured to acquire from positions on a surface of the chamber respective electrical signals in response to a conduction wave traversing the surface;
a display; and
a processor, configured to:
process the location signals to generate and present on the display a three-dimensional (3D) representation of the surface,
derive respective local activation times (LATs) from the respective electrical signals at the positions on the surface,
calculate a first time difference between the respective LATs at a first pair of the positions on the surface and a second time difference between the respective LATs at a second pair of the positions on the surface,
calculate first and second LAT-derived distances as respective products of the first time difference and the second time difference with a conduction velocity of the conduction wave,
identify an origin of an arrhythmia at a location on the surface such that a first difference in distances over the surface from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances over the surface from the location to the second pair of the positions is equal to the second LAT-derived distance, and
mark the identified origin on the representation of the surface on the display,
wherein the processor is configured to generate a mesh from the location coordinates, and wherein the distances over the surface comprise shortest distances measured along edges of the mesh,
wherein the mesh comprises a triangular mesh,
wherein the processor covers the triangular mesh to form a smooth continuous 3D surface, wherein the processor displays a graphic representation of the smooth 3D surface on the display, wherein the processor specifies equally spaced sample points on the triangular mesh, wherein the processor uses the sample points to perform discrete calculations on the continuous 3D surface.

2. The apparatus according to claim 1 , wherein the arrythmia comprises a single source arrythmia.

3. The apparatus according to claim 1 , and comprising the processor being configured to calculate the conduction velocity in response to a selected pair of points on the surface, the points being connected by a line segment parallel to a wavefront vector, and having respective LATs and positions.

4. The apparatus according to claim 1 , wherein the first difference in distances is equal to the first LAT-derived distance within a preset margin of error, and wherein the second difference in distances is equal to the second LAT-derived distance within the preset margin of error.

5. The apparatus according to claim 4 , wherein the preset margin of error is 1 mm.

Assignees

• Biosense Webster Israel Ltd
• Univ Rutgers

Inventors

• Hayam Gal
• Timofeyev Michael
• Bar-On Tal Haim
• Saluja Amardeep

Classifications

• A61B5/346

  Analysis of electrocardiograms · CPC title

• A61B5/283

  Invasive · CPC title

• A61B2018/00595

  Cauterization · CPC title

• A61B2576/023

  for the heart · CPC title

• A61B2018/1467

  using more than two electrodes on a single probe · CPC title