Gel forming composition for radiation dosimetry and radiation dosimeter using gel that is formed from said composition

Patent metadata

Field	Value
Publication number	US-11442181-B2
Application number	US-201716307073-A
Country	US
Kind code	B2
Filing date	Jun 19, 2017
Priority date	Jun 22, 2016
Publication date	Sep 13, 2022
Grant date	Sep 13, 2022

Abstract

A gel forming composition for radiation dosimetry, and a high sensitivity and high safety radiation dosimeter using a gel formed from the composition. A gel forming composition for radiation dosimetry comprising a gelator and a compound of Formula (1):(wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted C1-12 alkyl group, etc.; and R2 and R3 are each independently a hydrogen atom, an optionally substituted C1-12 alkyl group, an optionally substituted monovalent C6-12 aromatic group, or R2 and R3 form a 4- to 8-membered ring together with a carbon atom to which R2 and R3 are bonded, and the 4-to 8-membered ring may have 0 to 3 nitrogen atoms, oxygen atoms, or sulfur atoms as a ring atom, provided that R2 and R3 are not simultaneously a hydrogen atom).

First claim

The invention claimed is:

1. A gel forming composition for radiation dosimetry comprising a gelator and a compound of Formula (1):

wherein R 1 is a hydrogen atom, a halogen atom, an optionally substituted C 1-12 alkyl group, an optionally substituted C 1-12 alkyloxy group, an optionally substituted C 1-12 alkylthio group, an optionally substituted monovalent C 6-12 aromatic group, or a monovalent C 3-12 heteroaromatic group having at least one of a nitrogen atom, an oxygen atom, or a sulfur atom as a ring atom; and
R 2 and R 3 are each independently a hydrogen atom, an optionally substituted C 1-12 alkyl group, an optionally substituted monovalent C 6-12 aromatic group, or a monovalent C 3-12 heteroaromatic group having at least one of a nitrogen atom, an oxygen atom, or a sulfur atom as a ring atom, or R 2 and R 3 form a 4- to 8-membered ring together with a carbon atom to which R 2 and R 3 are bonded, and the 4- to 8-membered ring optionally has 0 to 3 nitrogen atoms, oxygen atoms, or sulfur atoms as a ring atom, provided that R 2 and R 3 are not simultaneously a hydrogen atom, and
wherein the gelator contains a water-soluble organic polymer (A) having an organic acid structure, an organic acid salt structure, or an organic acid anion structure, a silicate (B), and a dispersant (C) for the silicate.

2. The gel forming composition for radiation dosimetry according to claim 1 , wherein in Formula (1), R 2 and R 3 are each independently an optionally substituted C 1-12 alkyl group, an optionally substituted monovalent C 6-12 aromatic group, or a monovalent C 3-12 heteroaromatic group having at least one of a nitrogen atom, an oxygen atom, or a sulfur atom as a ring atom, or R 2 and R 3 form a 4- to 8-membered ring together with a carbon atom to which R 2 and R 3 are bonded, and the 4- to 8-membered ring optionally has 0 to 3 nitrogen atoms, oxygen atoms, or sulfur atoms as a ring atom.

3. The gel forming composition for radiation dosimetry according to claim 1 , wherein the gelator is one or two or more selected from the group consisting of agarose, xanthan gum, carrageenan, gellan gum, chitosan, and alginic acid.

4. The gel forming composition for radiation dosimetry according to claim 1 , wherein the water-soluble organic polymer (A) is a fully or partially neutralized polyacrylate having a weight average molecular weight of 1,000,000 to 10,000,000.

5. The gel forming composition for radiation dosimetry according to claim 1 , wherein the silicate (B) is one or two or more water-swellable silicate particles selected from the group consisting of smectite, bentonite, vermiculite, and mica.

6. The gel forming composition for radiation dosimetry according to claim 1 , wherein the dispersant (C) is one or two or more selected from the group consisting of sodium orthophosphate, sodium pyrophosphate, sodium tripolyphosphate, sodium tetraphosphate, sodium hexametaphosphate, sodium polyphosphate, sodium etidronate, sodium poly(meth)acrylate, ammonium poly(meth)acrylate, a sodium acrylate-sodium maleate copolymer, an ammonium acrylate-ammonium maleate copolymer, sodium hydroxide, hydroxylamine, sodium carbonate, sodium silicate, polyethylene glycol, polypropylene glycol, sodium humate, and sodium ligninsulfonate.

7. The gel forming composition for radiation dosimetry according to claim 6 , further comprising a crosslinker.

8. The gel forming composition for radiation dosimetry according to claim 1 , further comprising a deoxidizing agent.

9. The gel forming composition for radiation dosimetry according to claim 1 , wherein the gelator additionally contains a compound (D) having a divalent or higher positive charge.

10. The gel forming composition for radiation dosimetry according to claim 9 , wherein the compound (D) is at least one compound selected from the group consisting of a compound containing a group II element, a compound containing a transition metal element, a compound containing an amphoteric element, and a polyamine.

11. The gel forming composition for radiation dosimetry according to claim 9 , wherein the compound (D) is a hydrochloride, sulfate, diphosphate, silicate, or aluminate of magnesium, calcium, or aluminum.

12. The gel forming composition for radiation dosimetry according to claim 11 , wherein the compound (D) is, magnesium chloride, calcium chloride, magnesium sulfate, aluminum sulfate, calcium diphosphate, or magnesium aluminosilicate.

13. The gel forming composition for radiation dosimetry according to claim 1 , wherein the compound of Formula (1) is not N,N-dimethylacrylamide.

Assignees

• Riken
• Nissan Chemical Corp

Inventors

• Maeyama Takuya
• Fukasaku Kazuaki
• Ishida Yasuhiro
• Kudo Yoshihiro

Classifications

• C08L5/00 Primary

  Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00 · CPC title

• G01T1/04 Primary

  Chemical dosimeters (G01T1/06, G01T1/08 take precedence) · CPC title

• C08L5/12

  {Agar or} agar-agar {, i.e. mixture of agarose and agaropectin}; Derivatives thereof · CPC title

• C08K5/20

  Carboxylic acid amides · CPC title

• C08L5/04

  Alginic acid; Derivatives thereof · CPC title