Preparations
US-10492511-B2 · Dec 3, 2019 · US
Use of physiological cooling active ingredients, and compositions comprising such active ingredients
US11434220B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11434220-B2 |
| Application number | US-201816642954-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 31, 2018 |
| Priority date | Aug 31, 2017 |
| Publication date | Sep 6, 2022 |
| Grant date | Sep 6, 2022 |
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- Title
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- Abstract
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- Assignees and inventors
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- Key dates
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- First independent claim
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- CPC / IPC classifications
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Abstract
Official abstract text for this publication.
The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound selected from the group consisting of the following compounds: Structure Name €-3-(1,3-benzodioxol-5-yl)-N- phenyl-N-tetrahydrofuran-3-yl- prop-2-enamide €-3-(4-methoxyphenyl)-N- phenyl-N-tetrahydrofuran-3-yl- prop-2-enamide 2-(4-methylphenoxy)-N- phenyl-N-tetrahydrothiophen- 3-ylacetamide €-3-(1,3-benzodioxol-5-yl)-N- (2-pyridyl)-N- tetrahydrothiophen-3-yl-prop- 2-enamide €-3-(p-tolyl)-N-(2-pyridyl)-N- tetrahydrothiophen-3-ylprop-2- enamide €-3-(4-methoxyphenyl)-N-(2- pyridyl)-N-tetrahydrothiophen- 3-yl-prop-2-enamide €-3-phenyl-N-(2-pyridyl)-N- tetrahydrothiophen-3-ylprop-2- enamide €-3-(1,3-benzodioxol-5-yl)- N,N-bis(2-pyridyl)prop-2- enamide €-3-(1,3-benzodioxol-5-yl)-N- (1H-pyrazol-3-yl)-N- (tetrahydrofuran-2- ylmethyl)prop-2-enamide €-3-(p-tolyl)-N-(1H-pyrazol-3- yl)-N-(tetrahydrofuran-2- ylmethyl)prop-2-enamide €-3-(4-methoxyphenyl)-N-(1H- pyrazol-3-yl)-N- (tetrahydrofuran-2- ylmethyl)prop-2-enamide 2-(4-methylphenoxy)-N-(1H- pyrazol-3-yl)-N- (tetrahydrofuran-2- ylmethyl)acetamide €-3-(1,3-benzodioxol-5-yl)-N- (2-pyridyl)-N-(tetrahydrofuran- 2-ylmethyl)prop-2-enamide €-3-(p-tolyl)-N-(2-pyridyl)-N- (tetrahydrofuran-2- ylmethyl)prop-2-enamide €-3-(4-methoxyphenyl)-N-(2- pyridyl)-N-(tetrahydrofuran-2- ylmethyl)prop-2-enamide €-3-(1,3-benzodioxol-5-yl)-N- ethyl-N-(tetrahydrofuran-2- ylmethyl)prop-2-enamide N-ethyl-2-(4- methoxyphenoxy)-N- (tetrahydrofuran-2- ylmethyl)acetamide €-3-(1,3-benzodioxol-5-yl)-N- phenyl-N-(tetrahydrofuran-2- ylmethyl)prop-2-enamide €-N-phenyl-3-(p-tolyl)-N- (tetrahydrofuran-2- ylmethyl)prop-2-enamide €-3-(4-methoxyphenyl)-N- phenyl-N-(tetrahydrofuran-2- ylmethyl)prop-2-enamide 2-(4-methylphenoxy)-N- phenyl-N-(tetrahydrofuran-2- ylmethyl
Assignees
Inventors
Classifications
containing nitrogen as heteroatom · CPC title
with oxygen as the only hetero atom · CPC title
containing a five-membered ring with oxygen as a ring hetero atom · CPC title
Nitrogen atoms not forming part of a nitro radical · CPC title
- A61K8/49Primary
containing heterocyclic compounds · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US11434220B2 cover?
- The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such com…
- Who is the assignee on this patent?
- Basf Se, Symrise Ag
- What technology area does this patent fall under?
- Primary CPC classification A61K8/49. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Sep 06 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).