Methods for treatment of cancer with an anti-tigit antagonist antibody
US-2024424092-A1 · Dec 26, 2024 · US
US11426421B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11426421-B2 |
| Application number | US-201816212116-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 6, 2018 |
| Priority date | Jul 5, 2018 |
| Publication date | Aug 30, 2022 |
| Grant date | Aug 30, 2022 |
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Provided are a composition for preventing or improving inflammation, the composition including an extract of a seed of soybean Glycine max (L.) Merrill cultivar SCEL-1, and a method of preventing occurrence of inflammation in a subject or improving inflammation in a subject, the method including injecting the composition to a subject.
Opening claim text (preview).
What is claimed is: 1. A method of treating a human suffering from atopic dermatitis or chronic obstructive pulmonary disease, the method comprising administering a composition to the human in need thereof, wherein the composition comprises, as an active ingredient, an extract obtained by performing an extraction process on a seed of soybean Glycine max (L.) Merrill cultivar SCEL-1 by using water, C 1 -C 6 alcohol, or a mixture thereof, wherein the extract contains cyanidin-3-O-glucoside, procyanidin B2, and epicatechin, wherein an amount of procyanidin B2 contained in the extract by weight is two times or more than an amount of cyanidin-3-O-glucoside contained in the extract by weight, and wherein a representative sample of the seed is deposited with the Korean Agricultural Culture Collection (KACC), which is an International Depository Authority (IDA) under the Budapest Treaty on the International Recognition of the Deposit of Microorganisms for the Purpose of Patent Procedure under the accession number KACC 88002BP on Nov. 8, 2018. 2. The method of claim 1 , wherein a total amount of the cyanidin-3-O-glucoside, procyanidin B2, and epicatechin in the extract is in a range of 2.1% to 3.4% based on a total weight of the extract. 3. The method of claim 1 , wherein the extract comprises a mass ratio of cyanidin-3-O-glucoside:procyanidin B2 to be between 1:2.0 and 1:2.1. 4. The method of claim 1 , wherein an amount of the extract is in a range of 0.005% to 99.9% based on a total weight of the composition. 5. The method of claim 1 , wherein the human is also suffering from skin inflammation. 6. The method of claim 1 , wherein the composition is a food, a cosmetic composition, or a pharmaceutical composition.
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