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US-2024230643-A9 · Jul 11, 2024 · US
Production of fatty acid estolides
US11414684B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11414684-B2 |
| Application number | US-202117157162-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 25, 2021 |
| Priority date | Mar 26, 2015 |
| Publication date | Aug 16, 2022 |
| Grant date | Aug 16, 2022 |
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- Title
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Abstract
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It has been found that esterification of a hydroxy-fatty acid by a lipase can be coupled with oleate hydratase (OHase) generation of that hydroxy-FA from an unsaturated FA with a cis C9-C10 double bond, e.g. oleic acid, in a single aqueous buffered reaction medium at low temperature, e.g. 30° C. A simple one-pot enzymatic method to produce fatty acid estolides from one or more triglycerides, e.g. starting from a natural plant oil, is thereby enabled in which the same lipase catalyses both the initial hydrolysis of triglyceride and the final esterification step.
First claim
Opening claim text (preview).
The invention claimed is: 1. A recombinant oleate hydratase (OHase) immobilized on a particulate support wherein said OHase has an N-terminal His tag covalently linked to glutaraldehyde-activated chitosan composite particles in which smaller magnetic iron oxide particles are dispersed in a chitosan matrix. 2. A recombinant OHase according to claim 1 wherein said magnetic iron oxide particles are amino-terminated magnetic particles.
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Classifications
- C12N9/88Primary
Lyases (4.) · CPC title
Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats · CPC title
Oleate hydratase (4.2.1.53) · CPC title
Triglyceride splitting, e.g. by means of lipase · CPC title
Sources of fatty acids, e.g. natural glycerides, characterised by the nature, the quantities or the distribution of said acids · CPC title
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- What does patent US11414684B2 cover?
- It has been found that esterification of a hydroxy-fatty acid by a lipase can be coupled with oleate hydratase (OHase) generation of that hydroxy-FA from an unsaturated FA with a cis C9-C10 double bond, e.g. oleic acid, in a single aqueous buffered reaction medium at low temperature, e.g. 30° C. A simple one-pot enzymatic method to produce fatty acid estolides from one or more triglycerides, e.…
- Who is the assignee on this patent?
- Stichting Wageningen Res, Univ Delft Tech
- What technology area does this patent fall under?
- Primary CPC classification C12N9/88. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).