Compositions and methods for management of atrophic gastritis and colitis

US11413318B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11413318-B2
Application numberUS-202016903989-A
CountryUS
Kind codeB2
Filing dateJun 17, 2020
Priority dateJun 6, 2017
Publication dateAug 16, 2022
Grant dateAug 16, 2022

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention discloses a method for therapeutic management of atrophic gastritis and colitis using a composition comprising Bacillus coagulans MTCC 5856 individually or in combination with anthocyanins. The invention further discloses a method for preventing neoplastic transformation of mucosal cells in gastro-intestinal tract and improving gut barrier function in mammals using a composition comprising Bacillus coagulans MTCC 5856 individually or in combination with anthocyanins.

First claim

Opening claim text (preview).

We claim: 1. A method of therapeutic management of atrophic gastritis in mammals, said method comprising a step of administering an effective amount of a composition comprising Bacillus coagulans MTCC 5856, to the mammal in need of therapy for atrophic gastritis. 2. The method as in claim 1 , wherein therapeutic management of atrophic gastritis is brought about by improving gut barrier function by restoration of normal architecture of gastric mucosa with intact gastric epithelial cells. 3. The method as in claim 1 , wherein, therapeutic management of atrophic gastritis is brought about by reducing inflammatory markers selected from the group consisting of IL-17A, IL-1β, and IL-6. 4. The method as in claim 1 , wherein therapeutic management of atrophic gastritis is brought about by reducing lipid peroxidation and oxidative stress. 5. The method as in claim 1 , wherein therapeutic management of atrophic gastritis is brought about by reducing elevated levels of enzyme myeloperoxidase. 6. The method as in claim 1 , wherein the effective amount is 150 mg/kg bodyweight of Bacillus coagulans MTCC 5856, equivalent to 2 billion spores. 7. The method as in claim 1 , wherein the mammal is human.

Assignees

Inventors

Classifications

  • A61K31/352Primary

    condensed with carbocyclic rings, e.g. methantheline  {(cannabinoids A61K31/658)} · CPC title

  • A61K35/742Primary

    Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes · CPC title

  • Drugs for disorders of the alimentary tract or the digestive system · CPC title

  • Probiotics · CPC title

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What does patent US11413318B2 cover?
The present invention discloses a method for therapeutic management of atrophic gastritis and colitis using a composition comprising Bacillus coagulans MTCC 5856 individually or in combination with anthocyanins. The invention further discloses a method for preventing neoplastic transformation of mucosal cells in gastro-intestinal tract and improving gut barrier function in mammals using a com…
Who is the assignee on this patent?
Majeed Muhammed, Nagabhushanam Kalyanam, Bani Sarang, and 3 more
What technology area does this patent fall under?
Primary CPC classification A61K31/352. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).