Determination of a time-dependent contrast agent injection curve as a function of CT scan parameters

Patent metadata

Field	Value
Publication number	US-11406751-B2
Application number	US-201615138501-A
Country	US
Kind code	B2
Filing date	Apr 26, 2016
Priority date	May 4, 2015
Publication date	Aug 9, 2022
Grant date	Aug 9, 2022

Abstract

A method for the automatic determination of a contrast agent protocol for a contrast agent-enhanced medical imaging method is described. The method includes an overview recording of a region of interest of an object under examination. In addition, an image recording protocol including a plurality of recording parameters is defined on the basis of the overview recording. Furthermore, recording time points are determined for a plurality of z-positions of the region of interest on the basis of the image recording protocol. In addition, the structures acquired with the overview recording are assigned to the recording time points determined. Finally, a contrast agent protocol including the temporal course of a contrast agent injection curve is defined as a function of the acquired structures and the assigned recording time points. A contrast agent protocol determination device is also described, as well as an imaging medicinal device.

First claim

What is claimed is:

1. A method for automatically defining a contrast agent protocol for a contrast agent-enhanced medical imaging method, the method comprising:
performing, prior to injecting a contrast agent, an overview recording of a region of interest of an object under examination via a medical imaging device;
defining an image recording protocol based on image data recorded during the overview recording, the image recording protocol including a plurality of recording parameters including at least a scan rate of the medical imaging device;
determining, prior to injecting the contrast agent, recording time points based on the image recording protocol, the recording time points being for a plurality of z- positions of the region of interest;
assigning structures to the determined recording time points prior to injecting the contrast agent, the structures being acquired from the overview recording, the structures including at least one of an organ and a blood vessel; and
automatically defining, prior to injecting the contrast agent, the contrast agent protocol, including syncing administering the contrast agent as a function of the scan rate, the acquired structures and respectively assigned recording time points to the assigned structures, wherein the contrast agent protocol including a temporal course of a contrast agent injection curve is defined as the function of the acquired structures and assigned recording time points.

2. The method of claim 1 , wherein the automatically defining the contrast agent protocol includes a definition of a mixing ratio of the contrast agent with a saline chaser as a function of anatomy of the object under examination.

3. The method of claim 1 , wherein the automatically defining the contrast agent protocol includes a definition of a flow rate of an injected contrast agent as a function of time, a definition of a concentration of an injected contrast agent as a function of time, or both a definition of a flow rate of an injected contrast agent as a function of time and a definition of a concentration of an injected contrast agent as a function of time.

4. The method of claim 3 , wherein the medical imaging device is a CT system, and wherein the plurality of recording parameters of the image recording protocol include a rotation time of the CT system, a collimation of an X-ray beam, a spiral pitch of the CT system, a subcombination thereof, or a combination thereof.

5. The method of claim 1 , wherein the plurality of recording parameters of the image recording protocol include a size of the region of interest to be imaged.

6. The method of claim 5 , wherein the medical imaging device is a CT system, and wherein the plurality of recording parameters of the image recording protocol include a rotation time of the CT system, a collimation of an X-ray beam, a spiral pitch of the CT system, a subcombination thereof, or a combination thereof.

7. The method of claim 1 , wherein the automatically defining the contrast agent is based on empirical data, derived from collective of data, including arrival time of the contrast agent in one or more structures.

8. The method of claim 7 , wherein the empirical data includes typical times of arrival of the contrast agent in individual organs or vessels of the object under examination.

9. The method of claim 1 , wherein the automatically defining the contrast agent protocol is based on a model describing circulatory parameters of the object under examination.

10. The method of claim 9 , wherein the model is based on a flow rate of blood changing as a function of an anatomical position and a diameter of blood vessels through which blood flows.

11. The method of claim 1 , wherein the medical imaging method includes a magnetic resonance imaging method or a computed tomography method.

12. The method of claim 11 , wherein the automatically defining the contrast agent protocol includes a definition of a flow rate of a injected contrast agent as a function of time, a definition of a concentration of a injected contrast agent as a function of time, or both a definition of a flow rate of a injected contrast agent as a function of time and a definition of a concentration of a injected contrast agent as a-function of time.

13. The method of claim 11 , wherein the automatically defining the contrast agent protocol is based on a model describing circulatory parameters of the object under examination.

14. The method of claim 13 , wherein the model is based on flow rate of blood changing as a function of an anatomical position and a diameter of blood vessels through which blood flows.

15. A memory device of a control device of an imaging medicinal system, storing a computer program including program segments to carry out the method of claim 11 when the computer program is executed in the control device of the imaging medicinal system.

16. A non-transitory computer readable medium including stored program segments, readable-in and executable by a computing unit, to carry out the method of claim 11 when the program segments are executed by the computing unit.

17. A memory device of a control device of an imaging medicinal system, storing a computer program including program segments to carry out the method of claim 1 when the computer program is executed in the control device of the imaging medicinal system.

18. A non-transitory computer readable medium including stored program segments, readable-in and executable by a computing unit, to carry out the method of claim 1 when the program segments are executed by the computing unit.

19. An imaging method, the method comprising:
using the method of claim 1 to determine the contrast agent protocol; and
performing imaging, via the contrast agent-enhanced medical imaging method, using the determined contrast agent protocol.

20. The imaging method of claim 19 , further comprising:
sending a control signal for controlling a contrast agent injection to a contrast agent injection device after determining the contrast agent protocol.

21. The imaging method of claim 19 , wherein the imaging includes a contrast agent-enhanced depiction of region of interest to be imaged of the object under examination.

22. A contrast agent protocol determination device for automatically defining a contrast agent protocol for a contrast agent-enhanced medical imaging method comprising:
a non-transitory memory having computer-readable instructions stored thereon;
and
at least one processor configured to execute the computer-readable instructions to cause the contrast agent protocol determination device to
acquire raw data, prior to injecting a contrast agent, for an overview recording of a region of interest of an object under examination via a medical imaging device;
reconstruct image data from the acquired raw data;
define an image recording protocol including a plurality of recording parameters including at least a scan rate of the medical imaging device based on the image data;
determine, prior to injecting the contrast agent, recording time points for a plurality of z-positions of the region of interest;
assign structures to the determined recording time points prior to injecting the contrast agent, the structures being acquired from the overview recording, the structures including at least one of an organ and a blood vessel; and
automatically define, prior to injecting the contrast agent, the contrast agent protocol, including syncing administering the contrast agent as a function of the

Assignees

• Siemens Ag
• Bayer Pharma AG

Inventors

• Flohr Thomas
• Jost Gregor
• Pietsch Hubertus

Classifications

• A61B6/032 Primary

  Transmission computed tomography [CT] · CPC title

• A61B6/488

  involving pre-scan acquisition · CPC title

• A61B6/503

  for diagnosis of the heart · CPC title

• A61B6/466

  adapted to display 3D data · CPC title

• A61B6/5217

  extracting a diagnostic or physiological parameter from medical diagnostic data · CPC title