System with photonic biopsy device for obtaining pathological information

Patent metadata

Field	Value
Publication number	US-11406367-B2
Application number	US-201816018140-A
Country	US
Kind code	B2
Filing date	Jun 26, 2018
Priority date	Nov 2, 2012
Publication date	Aug 9, 2022
Grant date	Aug 9, 2022

Abstract

A biopsy device is provided comprising a tubular member, a hollow shaft and an elongated fiber body. The hollow shaft may have a distal end and a shaft, wherein a laterally (sidewardly) facing notch is formed in the distal portion of the shaft. The elongated fiber body may include at least one optical fiber, preferably at least two optical fibers, with a distal end. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The fiber body is movable within the shaft, between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.

First claim

The invention claimed is:

1. A system for obtaining pathological information, the system comprising:
a biopsy device comprising:
a tubular member having a distal end;
a hollow shaft having a distal end, wherein a sidewardly facing notch is formed in the hollow shaft adjacent the distal end of the hollow shaft, wherein the hollow shaft is movably accommodated within the tubular member;
an elongated fiber body configured to at least partially accommodate therein a plurality of optical fibers, the plurality of optical fibers having a distal end, wherein the elongated fiber body is: (i) accommodated within the hollow shaft and (ii) configured to remain at a fixed position during ejection of the hollow shaft from the distal end of the tubular member,
wherein the tubular member is movable between a first location in which the sidewardly facing notch is covered by the tubular member, and a second location in which the sidewardly facing notch is not covered by the tubular member, and
wherein the hollow shaft is movable between a first position in which the distal end of the plurality of optical fibers is located at a distal-most tip of the distal end of the hollow shaft with the elongated fiber body extending through the sidewardly facing notch, and a second position in which the distal end of the plurality of optical fibers is located proximally to the sidewardly facing notch; and
an insert arranged in a fixed position within a portion of the hollow shaft between the distal end of the hollow shaft and the sidewardly facing notch, the insert configured to close the portion of the hollow shaft from entry of tissue when the hollow shaft is in the second position, the insert comprising a plurality of guiding channels configured to receive the plurality of optical fibers when the hollow shaft is in the first position.

2. The system of claim 1 , wherein the elongated fiber body of the biopsy device comprises a bevel at a distal end of the elongated fiber body, with the distal end of the plurality of optical fibers located adjacent the bevel of the elongated fiber body, and wherein the bevel of the elongated fiber body is located adjacent the distal end of the hollow shaft, when the hollow shaft is in the first position.

3. The system of claim 1 , wherein the biopsy device further comprises a channel for injecting or extracting a fluid.

4. The system of claim 1 , wherein the sidewardly facing notch is configured to accommodate a tissue sample to be taken from a tissue.

5. The system of claim 1 , further comprising a suction device for applying vacuum, wherein the biopsy device further comprises a tissue retraction channel, wherein the suction device is configured to apply the vacuum to the tissue retraction channel.

6. The system of claim 1 , further comprising a console including a light source, a light detector and a processor configured to process signals provided by the light detector, the console being configured for in-vivo tissue inspection.

7. The system of claim 6 , further comprising a storage container configured to receive an extracted tissue sample and store pathology information obtained by an in-vivo tissue inspection and/or an ex-vivo tissue inspection.

8. The system of claim 1 , further comprising a tissue analysis processor configured to perform ex-vivo tissue inspection.

9. The system of claim 1 , wherein the tubular member is configured to cut a tissue located in the sidewardly facing notch when the tubular member is moved to the first location in which the sidewardly facing notch is covered by the tubular member.

10. The system of claim 1 , wherein the elongated fiber body is a solid body in which are provided a plurality of channels, and wherein the plurality of optical fibers are accommodated within the plurality of channels.

11. The system of claim 1 , wherein the hollow shaft is configured to eject in length to the second position in which the elongated fiber body faces proximally to the sidewardly facing notch after the ejection.

12. A system for obtaining pathological information, the system comprising:
a biopsy device comprising:
a tubular member having a distal end;
a hollow shaft having a distal end, wherein a sidewardly facing notch is formed in the hollow shaft adjacent the distal end of the hollow shaft, wherein the hollow shaft is movably accommodated within the tubular member; and
an elongated fiber body configured to accommodate therein a plurality of optical fibers, the plurality of optical fibers having a distal end, wherein the elongated fiber body is: (i) accommodated within the hollow shaft and (ii) configured to remain at a fixed position during ejection of the hollow shaft from the distal end of the tubular member; and

a console including a light source, a light detector and a processor configured to process signals provided by the light detector, the console being configured for in-vivo tissue characterization,
wherein the tubular member is movable between a first location in which the sidewardly facing notch is covered by the tubular member, and a second location in which the notch is not covered by the tubular member,
wherein the hollow shaft is movable between a first position in which the distal end of the plurality of optical fibers is located at a distal-most tip of the distal end of the hollow shaft with the elongated fiber body extending through the sidewardly facing notch, and a second position in which the distal end of the plurality of optical fibers is located proximally to the sidewardly facing notch, and
wherein the biopsy device further comprises an insert arranged in a fixed position within a portion of the hollow shaft between the distal end of the hollow shaft and the sidewardly facing notch, the insert configured to close the portion of the hollow shaft from entry of tissue when the hollow shaft is in the second position, the insert comprising a plurality of guiding channels configured to receive the plurality of optical fibers when the hollow shaft is in the first position.

13. The system of claim 12 , wherein the elongated fiber body of the biopsy device comprises a bevel at a distal end of the elongated fiber body, with the distal end of the plurality of optical fibers located adjacent the bevel of the elongated fiber body, and wherein the bevel of the elongated fiber body is located adjacent the distal end of the hollow shaft, when the hollow shaft is in the first position.

14. The system of claim 12 , wherein the biopsy device further comprises a channel for injecting or extracting a fluid.

15. The system of claim 12 , wherein the sidewardly facing notch is configured to accommodate a tissue sample to be taken from a tissue.

16. The system of claim 12 , further comprising a suction device for applying vacuum, wherein the biopsy device further comprises a tissue retraction channel, wherein the suction device is configured to apply the vacuum to the tissue retraction channel.

17. The system of claim 12 , further comprising a storage container configured to receive an extracted tissue sample and to store pathology information obtained by an in-vivo tissue inspection and/or an ex-vivo tissue inspection.

18. The system of claim 12 , further comprising a tissue analysis processor configured to perform ex-vivo tissue inspection.

19. The system of claim 12 , wherein the tubular member is configured to cut a tissue located in the sidewardly facing notch when the tubular member is moved to the first location in which the sidewardly facing notch is covered by the tubular member.

Assignees

• Koninklijke Philips Nv

Inventors

• Bierhoff Waltherus Cornelis Jozef
• Reich Christian
• Van Der Mark Martinus Bernardus
• Hendriks Bernardus Hendrikus Wilhelmus
• Van De Stolpe Anja
• Voss Stephan
• Winkel Axel
• Van Der Voort Marjolein
• Pully Vishnu Vardhan
• Lucassen Gerhardus Wilhelmus
• Van Den Berg-Dams Susanne Dorien
• Spliethoff Jarich Willem

Classifications

• A61B5/14552

  Details of sensors specially adapted therefor · CPC title

• A61B10/0275

  with sample notch, e.g. on the side of inner stylet · CPC title

• A61B5/14503

  invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence) · CPC title

• A61B1/015

  Control of fluid supply or evacuation · CPC title

• A61B5/1459

  invasive, e.g. introduced into the body by a catheter · CPC title