Device for utilizing transmission ultrasonography to enable ultrasound-guided placement of central venous catheters

Patent metadata

Field	Value
Publication number	US-11406353-B2
Application number	US-201916456732-A
Country	US
Kind code	B2
Filing date	Jun 28, 2019
Priority date	Sep 3, 2013
Publication date	Aug 9, 2022
Grant date	Aug 9, 2022

Abstract

Ultrasound is typically performed with the use of an external transcutaneous probe that emits ultrasonic energy and measures the timing of reflected waves, thus allowing measurement of fluid flow or formation of a two-dimensional image. Clinically, the modality is limited by attenuation of the signal with increasing depth of penetration of the ultrasound into tissues, as well as by similarities in echo-genicity between different tissues. The present invention includes a system in which an intravascular probe actively transmits ultrasound that can then be detected by in-line piezoelectric transducers without reflection. This signal can be overlaid onto traditional B-mode or Doppler representation. Furthermore, the present invention includes a signal processing system that will display a real-time graphical representation of the vascular anatomy in order to assist the surgeon or procedural radiologist in the placement of central venous catheters.

First claim

What is claimed is:

1. A method of placing a central venous catheter into a patient, comprising:
providing a guidewire to be positioned into a superior vena cava of the patient,
wherein the guidewire includes a first piezoelectric transducer at a distal end of the guidewire,
wherein the first piezoelectric transducer is configured to be stimulated in a detection frequency bandwidth associated with sounds waves emitted by an ultrasound probe,
wherein the first piezoelectric transducer is configured to create a first oscillating voltage based on being stimulated in the detection frequency bandwidth,
wherein the first piezoelectric transducer is configured to create first ultrasound pulses based on the first oscillating voltage,
wherein the first piezoelectric transducer is configured to transmit the first ultrasound pulses,
wherein the first ultrasound pulses are received by the ultrasound probe and processed to indicate a location of the first piezoelectric transducer, and
wherein an indication of the location of the first piezoelectric transducer is displayed as a first signal overlaid on an ultrasound image; and

providing the central venous catheter to be positioned over the guidewire and into the superior vena cava,
wherein the guidewire is to be removed based on the central venous catheter being positioned in the superior vena cava,
wherein a distal end of the central venous catheter includes a second piezoelectric transducer,
wherein the second piezoelectric transducer is configured to be stimulated in the detection frequency bandwidth associated with the sound waves emitted by the ultrasound probe,
wherein the second piezoelectric transducer is configured to create a second oscillating voltage based on being stimulated in the detection frequency bandwidth,
wherein the second piezoelectric transducer is configured to create second ultrasound pulses based on the second oscillating voltage,
wherein the second piezoelectric transducer is configured to transmit the second ultrasound pulses,
wherein the second ultrasound pulses are received by the ultrasound probe and processed to indicate a location of the second piezoelectric transducer, and
wherein an indication of the location of the second piezoelectric transducer is displayed as a second signal overlaid on the ultrasound image.

2. The method of claim 1 , wherein the ultrasound probe is an external probe.

3. The method of claim 1 , wherein the guidewire is a Seldinger-type wire.

4. The method of claim 1 , further comprising:
providing an introducer sheath for intravascular placement prior to providing the guidewire to be positioned in the superior vena cava.

5. The method of claim 1 , wherein the ultrasound image is a B-mode image associated with the ultrasound probe.

6. A device, comprising:
a stylet comprising a first piezoelectric transducer at a distal end of the stylet,
wherein the stylet is configured to be positioned into a superior vena cava of a patient, and
wherein the first piezoelectric transducer is configured to:
be stimulated in a detection frequency bandwidth associated with sounds waves emitted by an ultrasound probe,
create a first oscillating voltage based on being stimulated in the detection frequency bandwidth,
create first ultrasound pulses based on the first oscillating voltage, and
transmit the first ultrasound pulses to the ultrasound probe,
wherein the first ultrasound pulses are processed to indicate a location of the first piezoelectric transducer, and
wherein an indication of the location of the first piezoelectric transducer is displayed as a first signal overlaid on an ultrasound image; and

a central venous catheter comprising a second piezoelectric transducer at a distal end of the central venous catheter,
wherein the central venous catheter is configured to be positioned over the stylet and into the superior vena cava,
wherein the stylet is to be removed based on the central venous catheter being positioned in the superior vena cava, and
wherein the second piezoelectric transducer is configured to:
be stimulated in the detection frequency bandwidth,
create a second oscillating voltage based on being stimulated in the detection frequency bandwidth,
create second ultrasound pulses based on the second oscillation voltage, and
transmit the second ultrasound pulses to the ultrasound probe,
wherein the second ultrasound pulses are processed to indicate a location of the second piezoelectric transducer, and
wherein an indication of the location of the second piezoelectric transducer is displayed as a second signal overlaid on the ultrasound image.

7. The device of claim 6 , wherein the ultrasound probe is an external probe.

8. The device of claim 6 , wherein the ultrasound image is a B-mode image associated with the ultrasound probe.

9. The device of claim 6 , wherein the stylet is configured to be connected to a power source via a detachable coupling.

10. The device of claim 9 , wherein the power source is connected to synchronization circuitry and software.

11. A method for ultrasound-guided placement of a central venous catheter into a patient, comprising:
receiving, by a device, a first set of sound waves transmitted from an external ultrasound probe,
wherein a guidewire or stylet of the device is configured to be positioned in a superior vena cava of the patient, and
wherein a first piezoelectric transducer of the device is configured to be stimulated in a detection frequency bandwidth associated with the first set of sound waves transmitted by the external ultrasound probe;

creating, by the device, a first oscillating voltage based on the first piezoelectric transducer being stimulated in the detection frequency bandwidth;
creating, by the device, a second set of sound waves based on the first oscillating voltage;
transmitting, by the device, the second set of sound waves for a real-time graphical representation of a vascular anatomy associated with the patient,
wherein the real-time graphical representation of the vascular anatomy includes a representation of a location of the first piezoelectric transducer overlaid on a B-mode image associated with the external ultrasound probe;

receiving, by the device, a third set of sound waves transmitted from the external ultrasound probe,
wherein the device comprises the central venous catheter,
wherein the central venous catheter is configured to be positioned in the superior vena cava, and
wherein a second piezoelectric transducer of the device is configured to be stimulated in the detection frequency bandwidth,

creating, by the device, a second oscillating voltage based on the second piezoelectric transducer being stimulated in the detection frequency bandwidth;
creating, by the device, a fourth set of sound waves based on the second oscillating voltage; and

transmitting, by the device, the fourth set of sound waves for the real-time graphical representation of the vascular anatomy,
wherein the real-time graphical representation of the vascular anatomy includes a representation of a location of the second piezoelectric transducer overlaid on the B-mode image.

12. The method of claim 11 , wherein the guidewire or stylet is an intravascular ultrasound probe.

13. The method of claim 11 , wherein the guidewire or stylet is connected to a power source via a detachable coupling.

14. The method of claim 1 , wherein the central venous catheter is connected to a power source via a detachable coupling.

15. The method of claim 1 , wherein the central venous catheter is flexible.

16. The devi

Assignees

• Univ Johns Hopkins

Inventors

• Abdullah Fizan
• Goldstein Seth
• Boctor Emad

Classifications

• A61B8/12 Primary

  in body cavities or body tracts, e.g. by using catheters · CPC title

• A61B8/0841

  for locating instruments · CPC title

• A61B8/4218

  characterised by articulated arms · CPC title

• A61B8/4483

  characterised by features of the ultrasound transducer · CPC title

• A61B8/445

  Details of catheter construction · CPC title