Vascular cages and methods of making and using the same

Patent metadata

Field	Value
Publication number	US-11399845-B2
Application number	US-201816215507-A
Country	US
Kind code	B2
Filing date	Dec 10, 2018
Priority date	Dec 12, 2017
Publication date	Aug 2, 2022
Grant date	Aug 2, 2022

Abstract

A vascular cage comprises a self-expandable frame including a plurality of elongated flexible bands. The frame is configured to transition between a compressed configuration and an expanded configuration. The expanded frame may form a three-dimensional cage configured to surround an interior volume as the frame is deployed. At least some of the plurality of bands may have a substantially rectangular cross-section.

First claim

What is claimed is:

1. A vascular cage comprising:
a self-expandable frame including a plurality of elongated flexible bands connected to each other at opposite ends of the frame, said frame being configured to transition between a compressed configuration and an expanded configuration, wherein the expanded frame forms a three-dimensional cage configured to surround an interior volume as the frame is deployed, wherein at least some of the plurality of bands have a substantially rectangular cross-section; and wherein the plurality of bands, when in the compressed configuration, together form a rectangular cross-section;
a pusher wire having an attachment fixture thereon; and
a severable deployment junction located at proximal ends of the plurality of bands releasably connecting each of said plurality of bands to said pusher wire.

2. An occlusive system comprising:
the vascular cage of claim 1 ; and
a cage delivery catheter having a lumen configured to constrain the self-expandable frame in its compressed configuration and to release the self-expandable frame into a target location in a vasculature in its expanded configuration, wherein the lumen of the cage delivery catheter has a substantially rectangular cross-section.

3. The vascular cage of claim 1 , wherein at each of the plurality of the bands comprises a first bend when said frame is in its expanded configuration.

4. The vascular cage of claim 1 , wherein the substantially rectangular cross-section allows at least some of the plurality of bands to be packed more closely relative to a circular cross-section in a cage delivery catheter when the self-expandable frame is constrained in its compressed configuration in said catheter.

5. The vascular cage of claim 1 , wherein the substantially rectangular cross-section allows a higher density of bands relative to a circular cross-section to be packed in a cage delivery catheter with reduced empty space between adjacent bands when the self-expandable frame is constrained in its compressed configuration in said catheter.

6. The vascular cage of claim 1 , wherein at least one band comprises a cross-section having varying shape, size, area, and/or longitudinal thickness profile.

7. The vascular cage of claim 6 , wherein said band comprises a first end having a larger cross-sectional area than a second end.

8. The vascular cage of claim 6 , wherein said band comprises a first end having a different cross-sectional shape than a second end.

9. The vascular cage of claim 6 , wherein said cross-section having the varying shape, size, area, and/or longitudinal thickness profile is formed by preferential etching of said band.

10. The vascular cage of claim 1 , wherein the self-expandable frame is generally spherical or ovoid in its expanded configuration.

11. The vascular cage of claim 1 , wherein the self-expandable frame comprises at least one dimpled portion in its expanded configuration.

12. The vascular cage of claim 1 , further comprising a wire coil wrapped around a portion of at least some of the plurality of bands.

13. The vascular cage of claim 12 , wherein the wire coil comprises a substantially rectangular shaped cross-section.

14. The vascular cage of claim 13 , wherein the wire coil comprises a radio opaque material.

15. The vascular cage of claim 14 , wherein the radio opaque material comprises a metal selected from the group consisting of platinum and platinum alloys.

16. The vascular cage of claim 12 , wherein the wire coil is configured to provide structural reinforcement to said plurality of bands.

17. The vascular cage of claim 12 , wherein the wire coil is not wrapped around a distal portion of said plurality of bands in order to allow bendability or flexibility of the bands at said distal portions.

18. The occlusive system of claim 2 , wherein the cage delivery catheter comprises a shaft having the lumen, a sidewall, at least one urging element formed in the sidewall, and a first filament disposed in the lumen.

19. The vascular cage of claim 1 , wherein the three-dimensional cage provides an interior space allowing one or more embolic coils to be deployed therein or proximate thereto.

20. The vascular cage of claim 1 , wherein the self-expandable frame comprises three to ten elongated flexible bands.

21. The vascular cage of claim 20 , wherein the self-expandable frame preferentially comprises five to eight elongated flexible bands.

22. A method of occluding a vascular location, said method comprising:
providing the vascular cage of claim 1 ,
delivering the vascular cage while constrained in its compressed configuration to a target site in the vasculature,
releasing the vascular cage from constraint so that it expands to its expanded configuration at the target location.

23. The method of claim 22 , wherein delivering comprises:
positioning a distal end of a cage delivery catheter at a target location in a patient's vasculature,
advancing the vascular cage in its compressed configuration through a lumen of the cage delivery catheter.

24. The method of claim 22 , wherein releasing comprises releasing the vascular cage from the distal end of the cage delivery catheter so that the vascular cage self-expands at the target location.

25. The method of claim 22 , wherein the target location is an aneurysm.

26. The method of claim 22 , wherein the target location is a blood vessel lumen.

27. The method of claim 22 , further comprising delivering coils into the interior volume of the vascular cage or proximate to the vascular cage after the vascular cage has been released.

Assignees

• Penumbra Inc

Inventors

• Hui Delilah
• San Diego Edsel
• Tompkins Ben

Classifications

• A61B2017/12068

  detachable by heat · CPC title

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61B2017/00526

  Methods of manufacturing · CPC title

• A61B2017/00915

  for radioactive radiation · CPC title

• A61B17/12172

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title