Flow-type ion selective electrode, electrolyte concentration measuring device using the same, and biochemical automatic analyzer

Patent metadata

Field	Value
Publication number	US-11397162-B2
Application number	US-202017034528-A
Country	US
Kind code	B2
Filing date	Sep 28, 2020
Priority date	Jan 31, 2014
Publication date	Jul 26, 2022
Grant date	Jul 26, 2022

Abstract

There is provided an electrolyte measuring device that can decrease a liquid amount used for measurement, in which stable sealing can be provided in connecting passages of ion selective electrodes to each other with no gap, while maintaining high measurement accuracy of an existing ion selective electrode, and a residing sample liquid can be greatly decreased. In a flow-type ion selective electrode, a sealing member is used, which can be brought into intimate contact with a passage connecting unit to near a passage hole. A gap regulating member is provided to keep a gap between the electrodes constant and to prevent the sealing member from being excessively pressed. An electrode case has a structure suitable for the sealing member for allowing the alignment and holding of the sealing member.

First claim

The invention claimed is:

1. A device for measuring a sample liquid using an ion selective electrode, the device comprising:
an upstream side passage connection unit; and
a sealing member,
wherein the upstream side passage connection unit comprises:
a first passage penetrated through the upstream side passage connection unit; and
a passage connecting unit, configured to connect a second passage provided on the ion selective electrode,
wherein the passage connecting unit includes the sealing member for sealing a gap between the first passage of the upstream side passage connection unit and the second passage of the ion selective electrode,
wherein the sealing member is integrally formed of:
a sheet portion having a first surface connecting the upstream side passage connection unit and a second surface configured to connect the ion selective electrode, the sheet portion having an opening; and
a projection portion that projects from the sheet portion;
wherein rubber hardness of the sealing member is lower than rubber hardness of the upstream side passage connection unit, and
wherein the upstream side passage connection unit has a recess holding the projection portion of the sealing member so that the opening of the sheet portion is attached to an end portion of the first passage of the upstream side passage connection unit.

2. The device according to claim 1 , wherein one side surface of the recess has an open end in contact with the first passage of the upstream side passage connection unit.

3. The device according to claim 1 , wherein one side surface of the recess does not have an open end in contact with the first passage of the upstream side passage connection unit.

4. The device according to claim 1 , further comprising:
an electrode relative positioning projection disposed on a same side of the upstream side passage connection unit as the sealing member.

5. The device according to claim 1 , wherein the material of the sealing member is a rubber having a polymethylene type main chain, a rubber having silicon and oxygen on a main chain.

6. The device according to claim 1 , wherein the material of the sealing member is a rubber copolymer containing polyethylene, ethylene, propylene, and diene.

7. The device according to claim 1 , wherein the material of the sealing member is:
a rubber copolymer containing fluoro and a perfluoro alkyl group, or a perfluoro alkoxy group, on all of its side chains, or
a rubber copolymer containing fluoro and a perfluoro alkyl group, or a perfluoro alkoxy group, on its side chain.

8. An device for measuring a sample liquid using an ion selective electrode, the device comprising:
a downstream side passage connection unit; and
a sealing member,
wherein the downstream side passage connection unit comprises:
a first passage penetrated through the downstream side passage connection unit; and
a passage connecting unit, configured to connect a second passage provided on the ion selective electrode,
wherein the passage connecting unit includes the sealing member for sealing a gap between the first passage of the downstream side passage connection unit and the second passage of the ion selective electrode,
wherein the sealing member is integrally formed of:
a sheet portion having a first surface connecting the downstream side passage connection unit and a second surface configured to connect the ion selective electrode, the sheet portion having an opening; and
a projection portion that projects from the sheet portion;
wherein rubber hardness of the sealing member is lower than rubber hardness of the downstream side passage connection unit, and
wherein the downstream side passage connection unit has a recess holding the projection portion of the sealing member so that the opening of the sheet portion is attached to an end portion of the first passage of the downstream side passage connection unit.

9. The device according to claim 8 , wherein one side surface of the recess has an open end in contact with the first passage of the downstream side passage connection unit.

10. The device according to claim 8 , wherein one side surface of the recess does not have an open end in contact with the first passage of the downstream side passage connection unit.

11. The device according to claim 8 , further comprising:
an electrode relative positioning projection disposed on a same side of the downstream side passage connection unit as the sealing member.

12. The device according to claim 8 , wherein the material of the sealing member is a rubber having a polymethylene type main chain, a rubber having silicon and oxygen on a main chain.

13. The device according to claim 8 , wherein the material of the sealing member is a rubber copolymer containing polyethylene, ethylene, propylene, and diene.

14. The device according to claim 8 , wherein the material of the sealing member is:
a rubber copolymer containing fluoro and a perfluoro alkyl group, or a perfluoro alkoxy group, on all of its side chains, or
a rubber copolymer containing fluoro and a perfluoro alkyl group, or a perfluoro alkoxy group, on its side chain.

Assignees

• Hitachi High Tech Corp

Inventors

• Kishioka Atsushi
• Ishige Yu
• Ono Tetsuyoshi

Classifications

• F16J15/021

  with elastic packing (F16J15/08 takes precedence) · CPC title

• G01N27/27

  Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter · CPC title

• G01N27/333 Primary

  Ion-selective electrodes or membranes (glass electrodes G01N27/36) · CPC title

• G01N33/4915

  using flow cells (flow cytometry G01N15/14) · CPC title

• G01N27/413

  Concentration cells using liquid electrolytes {measuring currents or voltages in voltaic cells} · CPC title