Fluid management system and method

Patent metadata

Field	Value
Publication number	US-11397124-B2
Application number	US-202016734065-A
Country	US
Kind code	B2
Filing date	Jan 3, 2020
Priority date	Jan 7, 2019
Publication date	Jul 26, 2022
Grant date	Jul 26, 2022

Abstract

A fluid detection system includes a wicking material to draw fluid away from a first location with space limitations and proximate to a fluid device or a fluid interface. The wicking material draws the fluid to a remote fluid indicator at a second location. Contact between fluid and the remote fluid indicator produces a detectable alteration to the remote fluid indicator, and a non-contact optical sensor detects the alteration.

First claim

The invention claimed is:

1. A system for detecting fluid, the system comprising:
a cartridge comprising a wicking material configured to draw leaked fluid escaping a fluid retention boundary from a first location to a second location remote from the first location, wherein the wicking material extends from the first location to the second location and wherein the first location is disposed proximate to the fluid retention boundary so as the wicking material is to be exposed to the leaked fluid escaping the fluid retention boundary;
a remote fluid indicator located at the second location, wherein the remote fluid indicator contacts a portion of the wicking material at the second location, wherein a detectable alteration to the remote fluid indicator is produced when fluid contacts the remote fluid indicator; and
an optical sensor to detect the detectable alteration, wherein the optical sensor does not physically contact the remote fluid indicator.

2. The system of claim 1 , wherein the detectable alteration comprises a color change.

3. The system of claim 1 , wherein the remote fluid indicator comprises a tape indicator.

4. The system of claim 1 , wherein the wicking material comprises a woven material.

5. The system of claim 1 , wherein the wicking material comprises a nylon mesh fiber material.

6. The system of claim 1 , wherein the wicking material at the first location is proximate to a fluid-sensitive element.

7. The system of claim 1 , further comprising a communication component coupled to the optical sensor to produce a signal when the optical sensor detects the detectable alteration.

8. A system for detecting fluid, the system comprising:
a wicking material to draw fluid from a first location to a second location remote from the first location, wherein the wicking material extends from the first location to the second location and wherein the first location is disposed proximate to a fluid retention boundary so as to be exposed to fluid escaping the fluid retention boundary, wherein the wicking material is attached to a surface at the first location by a hydrophilic adhesive;
a remote fluid indicator located at the second location, wherein the remote fluid indicator contacts a portion of the wicking material at the second location, wherein a detectable alteration to the remote fluid indicator is produced when fluid contacts the remote fluid indicator; and
an optical sensor to detect the detectable alteration, wherein the optical sensor does not physically contact the remote fluid indicator.

9. The system of claim 7 , wherein the wicking material and the hydrophilic adhesive have a maximum combined thickness of about 120 μm at the first location.

10. A method of detecting fluid comprising:
contacting leaked fluid with a wicking material of a cartridge at a first location, the fluid having escaped a fluid retention boundary, wherein the wicking material extends from the first location to a second location remote from the first location;
drawing the fluid from the first location to the second location via the wicking material;
contacting the fluid with a remote fluid indicator in contact with the wicking material at the second location, wherein the contact between the fluid and the remote fluid indicator produces a detectable alteration to the remote fluid indicator;
detecting the detectable alteration via an optical sensor operatively associated with the remote fluid indicator, wherein the optical sensor does not physically contact the remote fluid indicator; and
producing a signal using a communication component coupled to the optical sensor when the optical sensor detects the detectable alteration.

11. The method of claim 10 , wherein the fluid contacting the wicking material has a volume of about 1 μL to about 500 μL.

12. The method of claim 10 , wherein the remote fluid indicator comprises a tape indicator.

13. The method of claim 10 , wherein the detectable alteration comprises a color change.

14. The method of claim 10 , wherein the wicking material comprises a woven material.

15. The method of claim 10 , wherein the wicking material is attached to a surface at the first location by a hydrophilic adhesive, wherein the wicking material and the hydrophilic adhesive have a maximum combined thickness of about 120 μm at the first location.

16. A fluid analysis system comprising:
a fluid cartridge with a fluid channel;
a fluidic device, wherein a portion of the fluidic device is disposed at a first location, wherein the fluidic device is disposed within the fluid cartridge and connected to the fluid channel at the first location;
a wicking material extending from the first location to a second location remote from the first location;
a remote fluid indicator at the second location, wherein the remote fluid indicator contacts a portion of the wicking material at the second location, wherein a detectable alteration to the remote fluid indicator is produced when fluid contacts the remote fluid indicator; and
an optical sensor to detect the detectable alteration, where the optical sensor does not physically contact the remote fluid indicator.

17. The system of claim 16 , further comprising an optical objective to optically analyze fluid within the fluidic device, wherein the optical objective is positioned about 100 μm to about 1000 μm from a viewing surface of the fluidic device.

18. The system of claim 16 , wherein the remote fluid indicator comprises a tape indicator.

19. The system of claim 16 , wherein the detectable alteration comprises a color change.

20. The system of claim 16 , wherein the wicking material comprises a woven material.

21. The system of claim 16 , further comprising a second wicking material surrounding the fluidic device, wherein the remote fluid indicator contacts a portion of the second wicking material at the second location.

22. The system of claim 16 , further comprising a communication component coupled to the optical sensor to produce a signal when the optical sensor detects the detectable alteration.

Assignees

• Illumina Inc

Inventors

• Holst Gregory L
• Taylor Jay

Classifications

• G01M3/04 Primary

  by detecting the presence of fluid at the leakage point · CPC title

• G01M3/38

  by using light (G01M3/02 takes precedence) · CPC title

• G01M3/047 Primary

  with photo-electrical detection means, e.g. using optical fibres · CPC title